Factors Influencing Maternal Adherence to Infant’s Nevirapine Prophylaxis in a Cross-Sectional Study Conducted at Mulago Hospital, Kampala, Uganda
International Journal of HIV/AIDS Prevention, Education and Behavioural Science
Volume 5, Issue 1, June 2019, Pages: 37-46
Received: Feb. 14, 2019; Accepted: Apr. 3, 2019; Published: May 6, 2019
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Caroline Kambugu Nabasirye, Department of Nursing and Midwifery, Faculty of Health Sciences, Lira University, Lira, Uganda
Ratib Mawa, Department of Public Health, Faculty of Health Sciences, Victoria University, Kampala, Uganda
Elizabeth Ayebare, Department of Nursing, School of Health Sciences, Makerere University College of Health Sciences, Kampala, Uganda
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To eliminate mother to child transmission of HIV, existing interventions might need to be scaled-up and rigorously implemented. One of the strategies to reduce vertical transmission of HIVis the 4-6weeks daily single oral dose ofNevirapine (NVP) or Zidovidinerecommended for newbornsto HIV positive mothers. Maternal optimal adherence to these anti-retroviral prophylaxis regimens is imperative to prevention of vertical transmission of HIV. Limited studies investigated maternal adherence to infant’s NVP prophylaxis regimen and associated factors. This study examined the level and factors influencing maternal adherence to infant’s NVPprophylaxis regimenat six weeks of age. Maternal adherence to infant’s NVP regimen was defined as dispensation of 95% of the total daily single dose of NVPsuspension to infants at 6 weeks of age. Maternal adherence, socio-demographic and psychosocial factors were measured using a pre-tested questionnaire. Bivariate analysis and binary logistic regression model were used to determine the level and factors influencing maternal adherence to infant’s NVP regimen respectively. Results showed that 77% of the mothers had optimal adherence. Maternal age ≥ 20 years and believe in the effectiveness of NVP in prevention of vertical transmission of HIV were associated with increased likelihood of adherence to infants NVP regimen (OR 6.18; 95% CI: 1.64-23.24) and (OR 12.69; 95% CI 3.07-52.44) respectively.In conclusion maternal maturity and perceived benefits of NVP seems to be important positive drivers of optimal adherence. This suggests the importance of considering psychosocial and demographic characteristics of mothers in policy and intervention designing.
Adherence, Prophylaxis, Postpartum Period, Mothers
To cite this article
Caroline Kambugu Nabasirye, Ratib Mawa, Elizabeth Ayebare, Factors Influencing Maternal Adherence to Infant’s Nevirapine Prophylaxis in a Cross-Sectional Study Conducted at Mulago Hospital, Kampala, Uganda, International Journal of HIV/AIDS Prevention, Education and Behavioural Science. Vol. 5, No. 1, 2019, pp. 37-46. doi: 10.11648/j.ijhpebs.20190501.15
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