Phytochemical Screening of Sclerocarya birrea (Anacardiaceae) and Khaya senegalensis (Meliaceae), Antidiabetic Plants
International Journal of Pharmacy and Chemistry
Volume 2, Issue 1, September 2016, Pages: 1-5
Received: Feb. 8, 2016; Accepted: Jun. 18, 2016; Published: Aug. 31, 2016
Views 3115      Downloads 135
Atto Virginie, Laboratory of Animal Physiology, UFR Biosciences University Felix Houphouēt Boigny Abidjan, Abidjan, Côte d’Ivoire
Koffi Dago Pierre, Endocrinology and Diabetology Service, CHU Yopougon Abidjan, Abidjan, Côte d’Ivoire
Monteomo Gnate Francois, Laboratory of Biochemistry, UFR Med. Sciences-University Felix Houphouēt-Boigny of Abidjan, Abidjan, Côte d’Ivoire
Adeoti Mansour Franck, Laboratory of Biochemistry, UFR Med. Sciences-University Felix Houphouēt-Boigny of Abidjan, Abidjan, Côte d’Ivoire
Article Tools
Follow on us
This study aimed at investigate the phytochemical screening of aqueous, methanolic, dichloromethane extracts of the stem barks of Sclerocarya birrea (Anarcadiaceae) and Khaya senegalensis (Meliaceae). Experiments were performed with the test tubes. The phytochemical analysis revealed the presence of polyphenols, flavonoids, saponides, triterpenes and tannins. We couldn’t found alkaloids and quinoids compounds in the tested extracts. Each of these phytochemical compounds has a specific mechanism for lowering blood sugar levels in diabetes rats. However, the large amount of chemical compounds confers to Sclerocarya birrea and Khaya senegalensis extracts its antidiabetic activities. So, that experience could justify the use of Sclerocarya birrea for diabetic therapeutics in traditional medicine.
Phytochemical Screening, Sclerocarya birrea, Khaya senegalensis, Mechanism, Diabetes
To cite this article
Atto Virginie, Koffi Dago Pierre, Monteomo Gnate Francois, Adeoti Mansour Franck, Phytochemical Screening of Sclerocarya birrea (Anacardiaceae) and Khaya senegalensis (Meliaceae), Antidiabetic Plants, International Journal of Pharmacy and Chemistry. Vol. 2, No. 1, 2016, pp. 1-5. doi: 10.11648/j.ijpc.20160201.11
Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abdelgaleil SA, Iwagawa T, Doe M, Nakatani M. Antifungal limonoids from the fruits of Khaya senegalensis. Fitoterapia, 2004; 77: 566-572.
Aké AL. Flore de la Côte d’Ivoire: catalogue, systématique, biogéographie et écologie. Boissiera. 2001, 1 vol. 57 p.
Bekro YA, Bekro MJA, Boua BB. Etude ethnobotanique et screening phytochimique de Caesalpinia benthamiana (Caesalpinaeae). J Sc Nat, 2007; 4, 2: 217-225.
Brahmachari G. Natural products in drug discovery: impacts and opportunities-an Assessment. In Bioactive natural products: opportunities and challenges in Medicinal chemistry, 1st Ed., World St Scientific Publishers, Singapore, 2012: 1-114.
Brock A, Herzfeld T, Paschke R, Koch M, Drager B. Pharmacognosie, Phytochimie, Plantes médicinales. Phytochemistry, 2006; 67 (18): 50-57.
Bruneton J. Pharmacognosie. Phytochimie. Plantes médicinales. Paris, 4 ème édit: Lavoisier Librairie, 2009; p. 259-264.
Chattopadhyay, R. R. A comparative evaluation of some blood sugar lowering agents of plant origin. J Ethnopharmacol, 1999, 67: 367-372.
Chidambara K, Vanitha A, Mahadeva M, Ravishankar G. Antioxidant and antimicrobial activity of Cissus quandrangularis LJ. Med. Food. 2003; 36: 2.
Debuigue G. Larousse des plantes qui guérissent. Librairie Larousse, 2010; p. 5-6.
Egharevba HO, Ibrahim JA, Abraham CH, Kunle OF. Photochemical constituents and herbarium specimens of commonly used antidiabetic medicinal plants found in Jos North, Plateau state. E J Folklore Medicine, 2015; 1, (1): 11-22.
Gaikwad SB, Mohan GK and Rani SM. Phytochemicals for Diabetes Management. Pharmaceutical Crops, 2014, 5 (Suppl 1: M2) 11-28.
Keita A, Mariko E, Haidara TK. Etude de l'activité hypoglycémiante des feuilles de Sclerocarya birrea (A. Rich) Hochst. (Anacardiaceae) Pharm. Méd. Trad. Afr. 1998, 10: 16-25.
Kerharo J, Adam JC. La pharmacopée sénégalaise traditionnelle: plantes médicinales et tropicales. Paris, Ed Vigot et frères, 1974; 433-35.
Kolawole OT, Kolawole SO, Ayankunle A A, Olaniran OI. Anti hyperglycemic Effect of Khaya senegalensis stem bark aqueous extract in Wistar rats. European Journal of Medicinal Plants, 2012; 2 (1 ): 66-73.
Marles RJ, Farnsworth NR. Antidiabetic plants and their active constituents. Phytomed, 1995; 2, 2: 137-89.
Martineau LC, Couture A, Spoor D, Benhaddou-Andaloussi A. Antidiabetic properties of the Canadian low bush blue berry Vaccinium angustifolium Ait. Phytomedicine, 2006, 13: 612-623.
Monteomo GF, Tehoua L, Ouattara H et al. Comparative antihyperglycemic activity of Sclerocarya birrea, Khaya senegalensis, Heliotropium indicum and Ocimum gratissimum to rats Wistar. Am J Biosciences, 2014; 2, 2: 60-63.
Nemlin J, Brunel JF. Travaux pratiques de matière médicale, 3 ème année, Paris, Masson, 1995-1996: 39-43.
N’doua LAR, Kouakou AJC, Aoussi S, GbogboM, Yapo AP et al. Effets hypoglycemique et antihyperglycemique de l’extrait ethanolique 70% de racines de Rauvolfia vomitoria afzel (apocynaceae). European Scientific Journal, 2015, 11, 6: 176-189.
N’Guessan K, Kadja B, Zirihi GN, Aké-Assi L. Screening phytochimique de quelques plantes médicinales ivoiriennes utilisées en pays Krobou (Agboville, Côte-d’Ivoire). Science and Nature. 2009, 6 (1): 1-15
Pan GY, Huang ZJ, Wang GJ, Fawcett JP, Liu Y and al. The antihyperglycaemic activity of berberine arises from a decrease of glucose absorption. Planta Med., 2003, 69, 632-636.
Pousset JL. Plantes médicinales d'Afrique, comment les reconnaître et les utiliser? Edisud, 2004; 287 pp.
Rafael F, Elena C, Marcedes DRC. Pharmacognosie, Phytochimie, Plantes médicinales. Phytochemistry, 2005; 66: 175-185.
Xia X, Ling W, Ma J, Xia M, Hou M and al. An anthocyanin-rich extract from black rice enhances atherosclerotic plaque stabilization in apolipoprotein E-deficient mice. J Nutr, 2006, 136 (8): 20-25.
World Health Organization (WHO). Report of the Inter-Regional Workshop WHO on the use of traditional medicine in primary health care, Ulanbator-Mongolia: WHO, 2007. 82 p
Zhang H, Derveer DV, Wang Xi, Chen F, Androulakis XM and al. 6 S, 8a-Dihydroxy-14, 15-Dihydrocarapin (Khayanone) from the Stem Bark of Khaya Senegalensis (Meliaceae): Isolation and its Crystal Structure. J Chem Crystallogr, 2007, 37: 463–467.
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
Tel: (001)347-983-5186