Evaluation of the Phytochemicals and Antimicrobial Activities of the Ethanolic, Hexane and Ethyl Acetate Extracts of Spigelia Anthelmia Leaves
International Journal of Pharmacy and Chemistry
Volume 3, Issue 3, May 2017, Pages: 29-32
Received: Sep. 3, 2016; Accepted: Apr. 14, 2017; Published: May 6, 2017
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Authors
Uzama Danlami, Chemistry Advanced Research Centre, Sheda Science and Technology Complex, Garki, Abuja, Nigeria
Osuagwu Eberechi Cecilia, Department of Forestry and Environmental Management, College of Natural Resources and Environmental Management, Micheal Okpara University of Agriculture, Umudike, Umuahia, Nigeria
Osuagwu Magnus Ifeanyi, Chemistry Advanced Research Centre, Sheda Science and Technology Complex, Garki, Abuja, Nigeria
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Abstract
The objective of this study was to determine the phytoconstituents and antimicrobial activities of the hexane, ethanolic and ethyl acetate extracts of Spigelia anthelmia leaves. The phytochemical analysis was carried out using standard methods. The Agar well diffusion method was adopted in carrying out the antimicrobial screening. The results of the phytochemical analysis indicated the presence of saponins, tannins, steroids, terpenoids, resins and volatile oils in hexane extract; saponins, alkaloids, tannins and balsams in ethanolic extract and tannins, steroids, terpenoids and volatile oils in ethyl acetate extract. The antimicrobial screening indicated that the hexane extract was active on Escherichia coli, Salmonela typhi, Klebsiela pneumonia and Pseudomonas ariginosa but inactive on staphylococcus aureus. The ethanolic extract was active on all the test organisms. The ethyl acetate extract was active on Escherichia coli, Salmonella typhi, Klebsiella pneumonia and Pseudomonas ariginosa but inactive on staphylococcus aureus. This indicated that the hexane, ethanolic and ethyl acetate extracts of Spigelia anthelmia leaves can serve as potential antibiotics in ethno medicines.
Keywords
Klebsiela Pneumonia, Phytochemical Analysis, Tannins, Agar well Diffusion, Ethno Medicines
To cite this article
Uzama Danlami, Osuagwu Eberechi Cecilia, Osuagwu Magnus Ifeanyi, Evaluation of the Phytochemicals and Antimicrobial Activities of the Ethanolic, Hexane and Ethyl Acetate Extracts of Spigelia Anthelmia Leaves, International Journal of Pharmacy and Chemistry. Vol. 3, No. 3, 2017, pp. 29-32. doi: 10.11648/j.ijpc.20170303.11
Copyright
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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