Electrochemical Oxidation Effect of Each Ascorbic Acid and Folic Acid on Lead Ions in Human Blood
International Journal of Pharmacy and Chemistry
Volume 3, Issue 3, May 2017, Pages: 33-40
Received: Sep. 21, 2016; Accepted: Nov. 26, 2016; Published: May 6, 2017
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Muhammed Mizher Radhi, Health and Medical Technology College, Radiological Techniques Department, Middle Technical University, Baghdad, Iraq
Sura Ali Al-Assady, Health and Medical Technology College, Radiological Techniques Department, Middle Technical University, Baghdad, Iraq
Nadia Tareq Barakat, Iraqi Center for Cancer and Medical Genetic Research, Almustensyria University, Baghdad, Iraq
Ammani Jassim Mohammed, Health and Medical Technology College, Analytical Lab. Techniques Department, Middle Technical University, Baghdad, Iraq
Ibtihal Hashim Aziz, Health and Medical Technology College, Analytical Lab. Techniques Department, Middle Technical University, Baghdad, Iraq
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Electrochemical studies by cyclic voltammetric (CV) method provide high potential for investigation of oxidant pollutant compounds such as Pb(II). Glassy carbon electrode (GCE) can be used for the potentiostatic analysis of the lead ions in different electrolyte especially human blood medium to studying the effect of the lead ions on the blood components. The results of this study were found that oxidation and reduction current peaks of lead ions in 1M KCl is high value and enhanced by adding ascorbic acid (AA) solution, while in human blood medium was disappearing the reduction current peak and enhance the oxidation current peak by lead ions. It means that lead ions in blood medium act as an oxidative reagent and causes problem in the decomposition of the blood component. Also, it was found that using folic acid (FA) solution with lead ions in blood medium causes the enhancement of reduction current peaks of lead ion and decreasing for oxidation current peaks, so this means that folic acid solution acts as antioxidative reagent in present of lead ions in blood medium, it may recommended to taking tablet of FA for the patients who suffers to lead pollution.
Pb(II), Cyclic Voltammetry, Human Blood, Redox Process, FA, AA
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Muhammed Mizher Radhi, Sura Ali Al-Assady, Nadia Tareq Barakat, Ammani Jassim Mohammed, Ibtihal Hashim Aziz, Electrochemical Oxidation Effect of Each Ascorbic Acid and Folic Acid on Lead Ions in Human Blood, International Journal of Pharmacy and Chemistry. Vol. 3, No. 3, 2017, pp. 33-40. doi: 10.11648/j.ijpc.20170303.12
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