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Electrochemical Oxidation Effect of Each Ascorbic Acid and Folic Acid on Lead Ions in Human Blood

Received: 21 September 2016    Accepted: 26 November 2016    Published: 6 May 2017
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Abstract

Electrochemical studies by cyclic voltammetric (CV) method provide high potential for investigation of oxidant pollutant compounds such as Pb(II). Glassy carbon electrode (GCE) can be used for the potentiostatic analysis of the lead ions in different electrolyte especially human blood medium to studying the effect of the lead ions on the blood components. The results of this study were found that oxidation and reduction current peaks of lead ions in 1M KCl is high value and enhanced by adding ascorbic acid (AA) solution, while in human blood medium was disappearing the reduction current peak and enhance the oxidation current peak by lead ions. It means that lead ions in blood medium act as an oxidative reagent and causes problem in the decomposition of the blood component. Also, it was found that using folic acid (FA) solution with lead ions in blood medium causes the enhancement of reduction current peaks of lead ion and decreasing for oxidation current peaks, so this means that folic acid solution acts as antioxidative reagent in present of lead ions in blood medium, it may recommended to taking tablet of FA for the patients who suffers to lead pollution.

Published in International Journal of Pharmacy and Chemistry (Volume 3, Issue 3)
DOI 10.11648/j.ijpc.20170303.12
Page(s) 33-40
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Pb(II), Cyclic Voltammetry, Human Blood, Redox Process, FA, AA

References
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Cite This Article
  • APA Style

    Muhammed Mizher Radhi, Sura Ali Al-Assady, Nadia Tareq Barakat, Ammani Jassim Mohammed, Ibtihal Hashim Aziz. (2017). Electrochemical Oxidation Effect of Each Ascorbic Acid and Folic Acid on Lead Ions in Human Blood. International Journal of Pharmacy and Chemistry, 3(3), 33-40. https://doi.org/10.11648/j.ijpc.20170303.12

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    ACS Style

    Muhammed Mizher Radhi; Sura Ali Al-Assady; Nadia Tareq Barakat; Ammani Jassim Mohammed; Ibtihal Hashim Aziz. Electrochemical Oxidation Effect of Each Ascorbic Acid and Folic Acid on Lead Ions in Human Blood. Int. J. Pharm. Chem. 2017, 3(3), 33-40. doi: 10.11648/j.ijpc.20170303.12

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    AMA Style

    Muhammed Mizher Radhi, Sura Ali Al-Assady, Nadia Tareq Barakat, Ammani Jassim Mohammed, Ibtihal Hashim Aziz. Electrochemical Oxidation Effect of Each Ascorbic Acid and Folic Acid on Lead Ions in Human Blood. Int J Pharm Chem. 2017;3(3):33-40. doi: 10.11648/j.ijpc.20170303.12

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  • @article{10.11648/j.ijpc.20170303.12,
      author = {Muhammed Mizher Radhi and Sura Ali Al-Assady and Nadia Tareq Barakat and Ammani Jassim Mohammed and Ibtihal Hashim Aziz},
      title = {Electrochemical Oxidation Effect of Each Ascorbic Acid and Folic Acid on Lead Ions in Human Blood},
      journal = {International Journal of Pharmacy and Chemistry},
      volume = {3},
      number = {3},
      pages = {33-40},
      doi = {10.11648/j.ijpc.20170303.12},
      url = {https://doi.org/10.11648/j.ijpc.20170303.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpc.20170303.12},
      abstract = {Electrochemical studies by cyclic voltammetric (CV) method provide high potential for investigation of oxidant pollutant compounds such as Pb(II). Glassy carbon electrode (GCE) can be used for the potentiostatic analysis of the lead ions in different electrolyte especially human blood medium to studying the effect of the lead ions on the blood components. The results of this study were found that oxidation and reduction current peaks of lead ions in 1M KCl is high value and enhanced by adding ascorbic acid (AA) solution, while in human blood medium was disappearing the reduction current peak and enhance the oxidation current peak by lead ions. It means that lead ions in blood medium act as an oxidative reagent and causes problem in the decomposition of the blood component. Also, it was found that using folic acid (FA) solution with lead ions in blood medium causes the enhancement of reduction current peaks of lead ion and decreasing for oxidation current peaks, so this means that folic acid solution acts as antioxidative reagent in present of lead ions in blood medium, it may recommended to taking tablet of FA for the patients who suffers to lead pollution.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Electrochemical Oxidation Effect of Each Ascorbic Acid and Folic Acid on Lead Ions in Human Blood
    AU  - Muhammed Mizher Radhi
    AU  - Sura Ali Al-Assady
    AU  - Nadia Tareq Barakat
    AU  - Ammani Jassim Mohammed
    AU  - Ibtihal Hashim Aziz
    Y1  - 2017/05/06
    PY  - 2017
    N1  - https://doi.org/10.11648/j.ijpc.20170303.12
    DO  - 10.11648/j.ijpc.20170303.12
    T2  - International Journal of Pharmacy and Chemistry
    JF  - International Journal of Pharmacy and Chemistry
    JO  - International Journal of Pharmacy and Chemistry
    SP  - 33
    EP  - 40
    PB  - Science Publishing Group
    SN  - 2575-5749
    UR  - https://doi.org/10.11648/j.ijpc.20170303.12
    AB  - Electrochemical studies by cyclic voltammetric (CV) method provide high potential for investigation of oxidant pollutant compounds such as Pb(II). Glassy carbon electrode (GCE) can be used for the potentiostatic analysis of the lead ions in different electrolyte especially human blood medium to studying the effect of the lead ions on the blood components. The results of this study were found that oxidation and reduction current peaks of lead ions in 1M KCl is high value and enhanced by adding ascorbic acid (AA) solution, while in human blood medium was disappearing the reduction current peak and enhance the oxidation current peak by lead ions. It means that lead ions in blood medium act as an oxidative reagent and causes problem in the decomposition of the blood component. Also, it was found that using folic acid (FA) solution with lead ions in blood medium causes the enhancement of reduction current peaks of lead ion and decreasing for oxidation current peaks, so this means that folic acid solution acts as antioxidative reagent in present of lead ions in blood medium, it may recommended to taking tablet of FA for the patients who suffers to lead pollution.
    VL  - 3
    IS  - 3
    ER  - 

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Author Information
  • Health and Medical Technology College, Radiological Techniques Department, Middle Technical University, Baghdad, Iraq

  • Health and Medical Technology College, Radiological Techniques Department, Middle Technical University, Baghdad, Iraq

  • Iraqi Center for Cancer and Medical Genetic Research, Almustensyria University, Baghdad, Iraq

  • Health and Medical Technology College, Analytical Lab. Techniques Department, Middle Technical University, Baghdad, Iraq

  • Health and Medical Technology College, Analytical Lab. Techniques Department, Middle Technical University, Baghdad, Iraq

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