International Journal of Pharmacy and Chemistry

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Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats

Received: 27 April 2020    Accepted: 20 May 2020    Published: 09 June 2020
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Abstract

The quest for the use of plants in the management of reproductive hormone dysfunction prompted this research. This study explored the effects of Ricinodendron heudelotti seed ethanol extract on some male reproductive hormones. Twenty five male albino rats were used. The animals were grouped into five and each group had five (5) albino rats. The extract was processed from the seeds of Ricinodendron heudelotti. Group A served as control, group B animals were administered with 300mg/kg.bw, while groups C, D and E animals were administered 450, 600 and 750 mg/kg.bw of the extract respectively for twenty one days. The animals were sacrificed and their blood samples were collected for the assay of testosterone, Follicle stimulating hormone (FSH) and Luteinizing hormone (LH). From the results obtained, the serum testosterone level of the experimental animals showed a concentration dependent increase in all the extract administered groups when compared with the value of the control group. FSH and LH levels showed an increase statistically (p≤0.05) in comparison to the level of the control. Ricinodendron heudelotti seed extract effectively increased the reproductive hormones of the animals by increasing the serum Testosterone, FSH and LH levels, hence suggests its effectiveness in enhancement of the male reproductive function.

DOI 10.11648/j.ijpc.20200602.11
Published in International Journal of Pharmacy and Chemistry (Volume 6, Issue 2, March 2020)
Page(s) 11-15
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Ricinodendron heudelotii, Testosterone, Follicle Stimulating Hormone, Luteinizing Hormone

References
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Author Information
  • Department of Biochemistry, Faculty of Science, Rivers State University, Port Harcourt, Nigeria; Department of Biochemistry, Faculty of Science, University of Port Harcourt, Port Harcourt, Nigeria

  • Department of Biochemistry, Faculty of Science, Rivers State University, Port Harcourt, Nigeria

  • Department of Medical Biochemistry, College of Medical Sciences, Rivers State University, Port Harcourt, Nigeria

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    Tamuno-boma Odinga, Ndidi Nwachoko, Christine Umanu Gabriel-Brisibe. (2020). Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats. International Journal of Pharmacy and Chemistry, 6(2), 11-15. https://doi.org/10.11648/j.ijpc.20200602.11

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    Tamuno-boma Odinga; Ndidi Nwachoko; Christine Umanu Gabriel-Brisibe. Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats. Int. J. Pharm. Chem. 2020, 6(2), 11-15. doi: 10.11648/j.ijpc.20200602.11

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    AMA Style

    Tamuno-boma Odinga, Ndidi Nwachoko, Christine Umanu Gabriel-Brisibe. Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats. Int J Pharm Chem. 2020;6(2):11-15. doi: 10.11648/j.ijpc.20200602.11

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  • @article{10.11648/j.ijpc.20200602.11,
      author = {Tamuno-boma Odinga and Ndidi Nwachoko and Christine Umanu Gabriel-Brisibe},
      title = {Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats},
      journal = {International Journal of Pharmacy and Chemistry},
      volume = {6},
      number = {2},
      pages = {11-15},
      doi = {10.11648/j.ijpc.20200602.11},
      url = {https://doi.org/10.11648/j.ijpc.20200602.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijpc.20200602.11},
      abstract = {The quest for the use of plants in the management of reproductive hormone dysfunction prompted this research. This study explored the effects of Ricinodendron heudelotti seed ethanol extract on some male reproductive hormones. Twenty five male albino rats were used. The animals were grouped into five and each group had five (5) albino rats. The extract was processed from the seeds of Ricinodendron heudelotti. Group A served as control, group B animals were administered with 300mg/kg.bw, while groups C, D and E animals were administered 450, 600 and 750 mg/kg.bw of the extract respectively for twenty one days. The animals were sacrificed and their blood samples were collected for the assay of testosterone, Follicle stimulating hormone (FSH) and Luteinizing hormone (LH). From the results obtained, the serum testosterone level of the experimental animals showed a concentration dependent increase in all the extract administered groups when compared with the value of the control group. FSH and LH levels showed an increase statistically (p≤0.05) in comparison to the level of the control. Ricinodendron heudelotti seed extract effectively increased the reproductive hormones of the animals by increasing the serum Testosterone, FSH and LH levels, hence suggests its effectiveness in enhancement of the male reproductive function.},
     year = {2020}
    }
    

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  • TY  - JOUR
    T1  - Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats
    AU  - Tamuno-boma Odinga
    AU  - Ndidi Nwachoko
    AU  - Christine Umanu Gabriel-Brisibe
    Y1  - 2020/06/09
    PY  - 2020
    N1  - https://doi.org/10.11648/j.ijpc.20200602.11
    DO  - 10.11648/j.ijpc.20200602.11
    T2  - International Journal of Pharmacy and Chemistry
    JF  - International Journal of Pharmacy and Chemistry
    JO  - International Journal of Pharmacy and Chemistry
    SP  - 11
    EP  - 15
    PB  - Science Publishing Group
    SN  - 2575-5749
    UR  - https://doi.org/10.11648/j.ijpc.20200602.11
    AB  - The quest for the use of plants in the management of reproductive hormone dysfunction prompted this research. This study explored the effects of Ricinodendron heudelotti seed ethanol extract on some male reproductive hormones. Twenty five male albino rats were used. The animals were grouped into five and each group had five (5) albino rats. The extract was processed from the seeds of Ricinodendron heudelotti. Group A served as control, group B animals were administered with 300mg/kg.bw, while groups C, D and E animals were administered 450, 600 and 750 mg/kg.bw of the extract respectively for twenty one days. The animals were sacrificed and their blood samples were collected for the assay of testosterone, Follicle stimulating hormone (FSH) and Luteinizing hormone (LH). From the results obtained, the serum testosterone level of the experimental animals showed a concentration dependent increase in all the extract administered groups when compared with the value of the control group. FSH and LH levels showed an increase statistically (p≤0.05) in comparison to the level of the control. Ricinodendron heudelotti seed extract effectively increased the reproductive hormones of the animals by increasing the serum Testosterone, FSH and LH levels, hence suggests its effectiveness in enhancement of the male reproductive function.
    VL  - 6
    IS  - 2
    ER  - 

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