Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis
International Journal of Clinical and Experimental Medical Sciences
Volume 6, Issue 5, September 2020, Pages: 85-90
Received: Sep. 15, 2020;
Accepted: Sep. 24, 2020;
Published: Oct. 7, 2020
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Nonyelum Obiechina, University Hospitals of Derby and Burton National Health Service Foundation Trust, Queens Hospital, Burton-on-Trent, United Kingdom
Atef Michael, Russel Hall Hospital, Dudley Group National Health Service Foundation Trust, Dudley, United Kingdom
Angela Nandi, University Hospitals of Derby and Burton National Health Service Foundation Trust, Queens Hospital, Burton-on-Trent, United Kingdom
Rachit Adlakha, Health Education England, Birmingham, United Kingdom
Amy Davis, Heart of England National Health Service Foundation Trust, Birmingham, United Kingdom
Alicia Barnes, University Hospitals of Derby and Burton National Health Service Foundation Trust, Queens Hospital, Burton-on-Trent, United Kingdom
Both hip fractures and stroke are common in elderly patients and hip fractures are especially prevalent in elderly stroke patients. This literature review is an attempt to explore the evidence for strategies to reduce hip fractures in stroke patients, the role of sarcopenia and osteoporosis in causing them and current and potential management strategies. A narrative approach was adopted in reviewing the evidence available on hip fractures in stroke patients, with regard to their incidence and prevalence, the role of sarcopenia and osteoporosis in their genesis and the evidence available for hip fracture prevention in stroke patients. I also attempt to explore the potential role of targeting muscle and bone as one unit in future therapeutic strategies. Although there are encouraging results from clinical trials on therapeutic interventions to prevent hip fractures in stroke patients, larger, more robustly designed studies are needed to validate many of the findings. Some evidence exists that suggest that hip fractures risk can be reduced in stroke patients but the findings need validation in larger more robust trials. Moreover it is clear that sarcopenia and osteoporosis are implicated in hip fractures in stroke and non-stroke elderly patients. A consensus on the definition of sarcopenia would also aid clarification of findings from studies.
Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis, International Journal of Clinical and Experimental Medical Sciences.
Vol. 6, No. 5,
2020, pp. 85-90.
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