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Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis

Received: 15 September 2020    Accepted: 24 September 2020    Published: 7 October 2020
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Abstract

Both hip fractures and stroke are common in elderly patients and hip fractures are especially prevalent in elderly stroke patients. This literature review is an attempt to explore the evidence for strategies to reduce hip fractures in stroke patients, the role of sarcopenia and osteoporosis in causing them and current and potential management strategies. A narrative approach was adopted in reviewing the evidence available on hip fractures in stroke patients, with regard to their incidence and prevalence, the role of sarcopenia and osteoporosis in their genesis and the evidence available for hip fracture prevention in stroke patients. I also attempt to explore the potential role of targeting muscle and bone as one unit in future therapeutic strategies. Although there are encouraging results from clinical trials on therapeutic interventions to prevent hip fractures in stroke patients, larger, more robustly designed studies are needed to validate many of the findings. Some evidence exists that suggest that hip fractures risk can be reduced in stroke patients but the findings need validation in larger more robust trials. Moreover it is clear that sarcopenia and osteoporosis are implicated in hip fractures in stroke and non-stroke elderly patients. A consensus on the definition of sarcopenia would also aid clarification of findings from studies.

Published in International Journal of Clinical and Experimental Medical Sciences (Volume 6, Issue 5)
DOI 10.11648/j.ijcems.20200605.11
Page(s) 85-90
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Stroke, Osteoporosis, Sarcopenia, Fractures, Osteosarcopenia

References
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Cite This Article
  • APA Style

    Nonyelum Obiechina, Atef Michael, Angela Nandi, Rachit Adlakha, Amy Davis, et al. (2020). Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis. International Journal of Clinical and Experimental Medical Sciences, 6(5), 85-90. https://doi.org/10.11648/j.ijcems.20200605.11

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    ACS Style

    Nonyelum Obiechina; Atef Michael; Angela Nandi; Rachit Adlakha; Amy Davis, et al. Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis. Int. J. Clin. Exp. Med. Sci. 2020, 6(5), 85-90. doi: 10.11648/j.ijcems.20200605.11

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    AMA Style

    Nonyelum Obiechina, Atef Michael, Angela Nandi, Rachit Adlakha, Amy Davis, et al. Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis. Int J Clin Exp Med Sci. 2020;6(5):85-90. doi: 10.11648/j.ijcems.20200605.11

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  • @article{10.11648/j.ijcems.20200605.11,
      author = {Nonyelum Obiechina and Atef Michael and Angela Nandi and Rachit Adlakha and Amy Davis and Alicia Barnes},
      title = {Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis},
      journal = {International Journal of Clinical and Experimental Medical Sciences},
      volume = {6},
      number = {5},
      pages = {85-90},
      doi = {10.11648/j.ijcems.20200605.11},
      url = {https://doi.org/10.11648/j.ijcems.20200605.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20200605.11},
      abstract = {Both hip fractures and stroke are common in elderly patients and hip fractures are especially prevalent in elderly stroke patients. This literature review is an attempt to explore the evidence for strategies to reduce hip fractures in stroke patients, the role of sarcopenia and osteoporosis in causing them and current and potential management strategies. A narrative approach was adopted in reviewing the evidence available on hip fractures in stroke patients, with regard to their incidence and prevalence, the role of sarcopenia and osteoporosis in their genesis and the evidence available for hip fracture prevention in stroke patients. I also attempt to explore the potential role of targeting muscle and bone as one unit in future therapeutic strategies. Although there are encouraging results from clinical trials on therapeutic interventions to prevent hip fractures in stroke patients, larger, more robustly designed studies are needed to validate many of the findings. Some evidence exists that suggest that hip fractures risk can be reduced in stroke patients but the findings need validation in larger more robust trials. Moreover it is clear that sarcopenia and osteoporosis are implicated in hip fractures in stroke and non-stroke elderly patients. A consensus on the definition of sarcopenia would also aid clarification of findings from studies.},
     year = {2020}
    }
    

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  • TY  - JOUR
    T1  - Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis
    AU  - Nonyelum Obiechina
    AU  - Atef Michael
    AU  - Angela Nandi
    AU  - Rachit Adlakha
    AU  - Amy Davis
    AU  - Alicia Barnes
    Y1  - 2020/10/07
    PY  - 2020
    N1  - https://doi.org/10.11648/j.ijcems.20200605.11
    DO  - 10.11648/j.ijcems.20200605.11
    T2  - International Journal of Clinical and Experimental Medical Sciences
    JF  - International Journal of Clinical and Experimental Medical Sciences
    JO  - International Journal of Clinical and Experimental Medical Sciences
    SP  - 85
    EP  - 90
    PB  - Science Publishing Group
    SN  - 2469-8032
    UR  - https://doi.org/10.11648/j.ijcems.20200605.11
    AB  - Both hip fractures and stroke are common in elderly patients and hip fractures are especially prevalent in elderly stroke patients. This literature review is an attempt to explore the evidence for strategies to reduce hip fractures in stroke patients, the role of sarcopenia and osteoporosis in causing them and current and potential management strategies. A narrative approach was adopted in reviewing the evidence available on hip fractures in stroke patients, with regard to their incidence and prevalence, the role of sarcopenia and osteoporosis in their genesis and the evidence available for hip fracture prevention in stroke patients. I also attempt to explore the potential role of targeting muscle and bone as one unit in future therapeutic strategies. Although there are encouraging results from clinical trials on therapeutic interventions to prevent hip fractures in stroke patients, larger, more robustly designed studies are needed to validate many of the findings. Some evidence exists that suggest that hip fractures risk can be reduced in stroke patients but the findings need validation in larger more robust trials. Moreover it is clear that sarcopenia and osteoporosis are implicated in hip fractures in stroke and non-stroke elderly patients. A consensus on the definition of sarcopenia would also aid clarification of findings from studies.
    VL  - 6
    IS  - 5
    ER  - 

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Author Information
  • University Hospitals of Derby and Burton National Health Service Foundation Trust, Queens Hospital, Burton-on-Trent, United Kingdom

  • Russel Hall Hospital, Dudley Group National Health Service Foundation Trust, Dudley, United Kingdom

  • University Hospitals of Derby and Burton National Health Service Foundation Trust, Queens Hospital, Burton-on-Trent, United Kingdom

  • Health Education England, Birmingham, United Kingdom

  • Heart of England National Health Service Foundation Trust, Birmingham, United Kingdom

  • University Hospitals of Derby and Burton National Health Service Foundation Trust, Queens Hospital, Burton-on-Trent, United Kingdom

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