Ethnobotanical Research on the Knowledge of <i>Vernonia amygdalina</i> Leaves in the Treatment of Liver Diseases in South Benin

Adjouavi Yvette Deguenon; Bernadin Manou Elegbede; Théodore Soussia; Kissao Gnandi; Patrick Aleodjrodo Edorh; Guillaume Koffivi Ketoh

doi:doi:10.11648/j.jher.20200603.11

Ethnobotanical Research on the Knowledge of Vernonia amygdalina Leaves in the Treatment of Liver Diseases in South Benin

Adjouavi Yvette Deguenon, Bernadin Manou Elegbede, Théodore Soussia, Kissao Gnandi, Patrick Aleodjrodo Edorh, Guillaume Koffivi Ketoh

Published in Journal of Health and Environmental Research (Volume 6, Issue 3)

Received: 20 May 2020 Accepted: 1 June 2020 Published: 9 June 2020

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Abstract

Most of the inhabitants of South Benin use medicinal plants to treat various pathologies. Several research studies have cited Vernonia amygdalina as a hepatoprotective medicinal plant. The objective of this work is to list the medicinal plants made available to the population to treat liver diseases by herbalists and to verify their level of knowledge in relation to the use of Vernonia amygdalina. The methodology consists of conducting a semi-structured survey of herbalists in markets, on sites where medicinal plants are sold and in households. This methodology allowed us to identify 38 species of medicinal plants belonging to 20 families. The best represented species is Bridelia ferruginea (10) of the family Euphobiaceae. The Rubiaceae family is the most represented (16). The organ of the plant most frequently used in recipes is the root (47). Five hundred and fifty-two households (552) responded to our questions. 64% use the leaves of Vernonia amygdalina for nutrition against 36% for therapeutic use. 68% are supplied from distant fields, 13% from urban areas and 19% from market gardening sites. 35% say they have no information about its use in phytotherapy, 21% use it for intestinal ailments, 18% for the treatment of malaria, 13% for oral diseases, 12% for other pathologies. The frequency of use (four times a week) is best represented for nutrition and phytotherapy. In conclusion, Vernonia amygdalina is very little known in phytotherapy despite the various researches carried out on this plant. Researchers must promote medicinal plants that are very easy to grow in order to limit the offer to users of rare plants in danger of extinction.

Published in	Journal of Health and Environmental Research (Volume 6, Issue 3)
DOI	10.11648/j.jher.20200603.11
Page(s)	44-50
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Vernonia amygdalina, Ethnobotanical Investigation, Liver Diseases

References

[1]	Sehonou J, Kodjoh N, Sake K, Mouala C (2010). Hepatic cirrhosis in Cotonou (Republic of Benin): clinical aspects and factors related to death. Med. Trop. 70, 4. 375-378.
[2]	Mégarbane B, Deye N, Baud F (2007). Toxic hepatitis: Mechanisms of toxicity and specific pharmacological agents. Journal homepage, 16, 632-642.
[3]	Labbe G, Pessayre D, Fromenty B (2008). Drug-induced liver injury through mitochondrial dysfunction: mechanisms and detection during preclinical safety studies. Fundamental and clinical pharmacology; 22, 4, 335-353.
[4]	WHO (2002). WHO Strategy for Traditional Medicine for 2002-2005. WHO/EDM/TRM/2002. Genève Suisse, pp 26-30.
[5]	Guinnin FDF, Sacramento TI, Sezan A, Ategbo JM (2015). Ethnobotanical study of medicinal plants used in the traditional treatment of viral hepatitis B and C in some departments of Benin. International Journal of Biological and Chemical Sciences. 9 (3) 1354-1366.
[6]	Mangambu M., Van Diggelen R., Mwanga Mwanga JC., Ntahobavuka H. Malaisse F. & Robbrecht E. (2012). Ethnopteridological study, extinction risk assessment and conservation strategies in the vicinity of the Kahuzi Biega National Park in D. R. Congo. International Journal of Tropical Ecology and Geography 36 (1/2), pp 137-145.
[7]	Yeap SK, Ho YW, Beh BK, Liang WS, Ky H, Yousr AHN and Alitheen NB (2010). Vernonia amygdalina, an ethnoveterinary and ethnomedical used green vegetable with multiple bioactivities. Journal of Medicinal Plants Research. 4 (25), pp. 2787-2812.
[8]	Atangwho IJ, Edet EE, Uti DE, Obi AU, Asmawi ZM, Ahmad M (2012). Biochemical and histological impact of Vernonia amygdalina supplemented diet in obese rats Saudi Journal of Biological Sciences 19, 385-392.
[9]	Iroanya OO, Adebesin OA, Okpuzor J (2014). Evaluation of the Hepato and Nephron-Protective Effect of a Polyherbal Mixture using Wistar Albino Rats. Journal of Clinical and Diagnostic Research. 8 (6): HC15-HC21.
[10]	Kamatenesi-Mugisha MM, Oryem-Origa H (2007). Medicinal plants used in some gynaecological morbidity ailments in western Uganda. African Journal of Ecology, 45 (Suppl. 1). 34-40.
[11]	Abuti JRS, Kukunda CB, Waako PJ (2010). Medicinal plants used by traditional medicine practitioners in the treatment of tuberculosis and related ailments in Uganda. Journal of Ethnopharmacology, 127, 130-136.
[12]	Tilahun T (2009). Ethnobotanical study of knowledge and medicinal plants use by the people in Dek Island in Ethiopia. Journal of Ethnopharmacology, 124, 69-78.
[13]	Africa Council (2006). Monograph of the commune of Cotonou 47p.
[14]	Africa Council (2006). Monograph of the commune of Abomey-Calavi72p.
[15]	Africa Council (2006). Monograph of the commune of Ouidah. 44p.
[16]	Kande B, Yao K, Allah-Kouadio E, Kone MW (2018). Survey on the use and effect of herbal medicines in hepatic patients hospitalized at the Medicine and Hepatogastroenterology Department of the University Hospital Center (CHU) of Cocody in Côte d'Ivoire. Journal of Applied Biosciences. 130: 13220-13231.
[17]	Adetutu A and Olorunnisola OS. (2013). Hepatoprotective Potential of Some Local Medicinal Plants against 2-Acetylaminoflourene-Induced Damage in Rat. Journal of Toxicology. 5p.
[18]	Bitsindou M, Lejoly J et Van Essghe K (1993). Plants used against liver diseases in traditional African medicine. Proceedings of the 2nd EuropCen Colloquium of Ethnopharmacology and Island International Conference of Ethnomedicine, Heidelberg, 24-27.
[19]	Djiguida M (2005). Evaluation of three recipes in the traditional treatment of hepatitis B in Mali. Faculty of Medicine, Pharmacy and Odonto -Stomatology. University of Bamako. 94p.
[20]	Tubéry P, Ragot J, lagarde P, Authier-derivaux d, Pidoux M, Rasolohery C, Bourdy G (2015). Composition and Functional Properties of Vernonia amygdalina Vegetable Leaf Protein Concentrates Greener. Journal of Agricultural Sciences. 3 (3), pp. 204-210.
[21]	Ott M, Thyagarajan SP, Gupta S (1997). Phyllanthus amarus suppresses hepatitis B virus by interrupting interactions between HBV enhancer I and cellular transcription factors. European Journal of Clinical. Investigation. 27 (11), 908-915.
[22]	Yehouenou EAP, Soton A, Azocli D, Acakpo H, Boco M, Fourn L, Houinsa D, Keke JC et Fayomi B, (2010). Contamination of soil, water and market garden produce by toxic substances and heavy metals at the Houéyiho site (Cotonou) in the Republic of Benin. Int. J. Biol. Chem. Sci. 4 (6): 2160-2168.
[23]	Kalonda MD, Tshikongo AK, koto KKF, Busambwa KC, Bwalya KY, Cansa MH, Tambwe KJL, Kalala LZ, Otshudi AL (2015). Profile of heavy metals contained in commonly consumed food crops in some mining areas of Katanga Province. Journal of Applied Biosciences 96: 9049–9054.

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APA Style

Adjouavi Yvette Deguenon, Bernadin Manou Elegbede, Théodore Soussia, Kissao Gnandi, Patrick Aleodjrodo Edorh, et al. (2020). Ethnobotanical Research on the Knowledge of Vernonia amygdalina Leaves in the Treatment of Liver Diseases in South Benin. Journal of Health and Environmental Research, 6(3), 44-50. https://doi.org/10.11648/j.jher.20200603.11

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ACS Style

Adjouavi Yvette Deguenon; Bernadin Manou Elegbede; Théodore Soussia; Kissao Gnandi; Patrick Aleodjrodo Edorh, et al. Ethnobotanical Research on the Knowledge of Vernonia amygdalina Leaves in the Treatment of Liver Diseases in South Benin. J. Health Environ. Res. 2020, 6(3), 44-50. doi: 10.11648/j.jher.20200603.11

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AMA Style

Adjouavi Yvette Deguenon, Bernadin Manou Elegbede, Théodore Soussia, Kissao Gnandi, Patrick Aleodjrodo Edorh, et al. Ethnobotanical Research on the Knowledge of Vernonia amygdalina Leaves in the Treatment of Liver Diseases in South Benin. J Health Environ Res. 2020;6(3):44-50. doi: 10.11648/j.jher.20200603.11

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@article{10.11648/j.jher.20200603.11,
  author = {Adjouavi Yvette Deguenon and Bernadin Manou Elegbede and Théodore Soussia and Kissao Gnandi and Patrick Aleodjrodo Edorh and Guillaume Koffivi Ketoh},
  title = {Ethnobotanical Research on the Knowledge of Vernonia amygdalina Leaves in the Treatment of Liver Diseases in South Benin},
  journal = {Journal of Health and Environmental Research},
  volume = {6},
  number = {3},
  pages = {44-50},
  doi = {10.11648/j.jher.20200603.11},
  url = {https://doi.org/10.11648/j.jher.20200603.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jher.20200603.11},
  abstract = {Most of the inhabitants of South Benin use medicinal plants to treat various pathologies. Several research studies have cited Vernonia amygdalina as a hepatoprotective medicinal plant. The objective of this work is to list the medicinal plants made available to the population to treat liver diseases by herbalists and to verify their level of knowledge in relation to the use of Vernonia amygdalina. The methodology consists of conducting a semi-structured survey of herbalists in markets, on sites where medicinal plants are sold and in households. This methodology allowed us to identify 38 species of medicinal plants belonging to 20 families. The best represented species is Bridelia ferruginea (10) of the family Euphobiaceae. The Rubiaceae family is the most represented (16). The organ of the plant most frequently used in recipes is the root (47). Five hundred and fifty-two households (552) responded to our questions. 64% use the leaves of Vernonia amygdalina for nutrition against 36% for therapeutic use. 68% are supplied from distant fields, 13% from urban areas and 19% from market gardening sites. 35% say they have no information about its use in phytotherapy, 21% use it for intestinal ailments, 18% for the treatment of malaria, 13% for oral diseases, 12% for other pathologies. The frequency of use (four times a week) is best represented for nutrition and phytotherapy. In conclusion, Vernonia amygdalina is very little known in phytotherapy despite the various researches carried out on this plant. Researchers must promote medicinal plants that are very easy to grow in order to limit the offer to users of rare plants in danger of extinction.},
 year = {2020}
}

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TY - JOUR
T1 - Ethnobotanical Research on the Knowledge of Vernonia amygdalina Leaves in the Treatment of Liver Diseases in South Benin
AU - Adjouavi Yvette Deguenon
AU - Bernadin Manou Elegbede
AU - Théodore Soussia
AU - Kissao Gnandi
AU - Patrick Aleodjrodo Edorh
AU - Guillaume Koffivi Ketoh
Y1 - 2020/06/09
PY - 2020
N1 - https://doi.org/10.11648/j.jher.20200603.11
DO - 10.11648/j.jher.20200603.11
T2 - Journal of Health and Environmental Research
JF - Journal of Health and Environmental Research
JO - Journal of Health and Environmental Research
SP - 44
EP - 50
PB - Science Publishing Group
SN - 2472-3592
UR - https://doi.org/10.11648/j.jher.20200603.11
AB - Most of the inhabitants of South Benin use medicinal plants to treat various pathologies. Several research studies have cited Vernonia amygdalina as a hepatoprotective medicinal plant. The objective of this work is to list the medicinal plants made available to the population to treat liver diseases by herbalists and to verify their level of knowledge in relation to the use of Vernonia amygdalina. The methodology consists of conducting a semi-structured survey of herbalists in markets, on sites where medicinal plants are sold and in households. This methodology allowed us to identify 38 species of medicinal plants belonging to 20 families. The best represented species is Bridelia ferruginea (10) of the family Euphobiaceae. The Rubiaceae family is the most represented (16). The organ of the plant most frequently used in recipes is the root (47). Five hundred and fifty-two households (552) responded to our questions. 64% use the leaves of Vernonia amygdalina for nutrition against 36% for therapeutic use. 68% are supplied from distant fields, 13% from urban areas and 19% from market gardening sites. 35% say they have no information about its use in phytotherapy, 21% use it for intestinal ailments, 18% for the treatment of malaria, 13% for oral diseases, 12% for other pathologies. The frequency of use (four times a week) is best represented for nutrition and phytotherapy. In conclusion, Vernonia amygdalina is very little known in phytotherapy despite the various researches carried out on this plant. Researchers must promote medicinal plants that are very easy to grow in order to limit the offer to users of rare plants in danger of extinction.
VL - 6
IS - 3
ER -

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Author Information

Adjouavi Yvette Deguenon

Department of Biochemistry and Cell Biology, Faculty of Science, University of Abomey-Calavi (UAC), Godomey, Benin; Department of Physiology/Pharmacology, Faculty of Science, University of Lome (UL), Lomé, Togo
Bernadin Manou Elegbede

National Water Institute, University of Abomey-Calavi (UAC), Godomey, Benin
Théodore Soussia

National Medical and Health Institute, University of Abomey-Calavi (UAC), Godomey, Benin
Kissao Gnandi

Department of Geology, Faculty of Science, University of Lome (UL), Lomé, Togo
Patrick Aleodjrodo Edorh

Department of Biochemistry and Cell Biology, Faculty of Science, University of Abomey-Calavi (UAC), Godomey, Benin
Guillaume Koffivi Ketoh

Department of Physiology/Pharmacology, Faculty of Science, University of Lome (UL), Lomé, Togo

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APA Style

Adjouavi Yvette Deguenon, Bernadin Manou Elegbede, Théodore Soussia, Kissao Gnandi, Patrick Aleodjrodo Edorh, et al. (2020). Ethnobotanical Research on the Knowledge of Vernonia amygdalina Leaves in the Treatment of Liver Diseases in South Benin. Journal of Health and Environmental Research, 6(3), 44-50. https://doi.org/10.11648/j.jher.20200603.11

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ACS Style

Adjouavi Yvette Deguenon; Bernadin Manou Elegbede; Théodore Soussia; Kissao Gnandi; Patrick Aleodjrodo Edorh, et al. Ethnobotanical Research on the Knowledge of Vernonia amygdalina Leaves in the Treatment of Liver Diseases in South Benin. J. Health Environ. Res. 2020, 6(3), 44-50. doi: 10.11648/j.jher.20200603.11

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AMA Style

Adjouavi Yvette Deguenon, Bernadin Manou Elegbede, Théodore Soussia, Kissao Gnandi, Patrick Aleodjrodo Edorh, et al. Ethnobotanical Research on the Knowledge of Vernonia amygdalina Leaves in the Treatment of Liver Diseases in South Benin. J Health Environ Res. 2020;6(3):44-50. doi: 10.11648/j.jher.20200603.11

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@article{10.11648/j.jher.20200603.11,
  author = {Adjouavi Yvette Deguenon and Bernadin Manou Elegbede and Théodore Soussia and Kissao Gnandi and Patrick Aleodjrodo Edorh and Guillaume Koffivi Ketoh},
  title = {Ethnobotanical Research on the Knowledge of Vernonia amygdalina Leaves in the Treatment of Liver Diseases in South Benin},
  journal = {Journal of Health and Environmental Research},
  volume = {6},
  number = {3},
  pages = {44-50},
  doi = {10.11648/j.jher.20200603.11},
  url = {https://doi.org/10.11648/j.jher.20200603.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jher.20200603.11},
  abstract = {Most of the inhabitants of South Benin use medicinal plants to treat various pathologies. Several research studies have cited Vernonia amygdalina as a hepatoprotective medicinal plant. The objective of this work is to list the medicinal plants made available to the population to treat liver diseases by herbalists and to verify their level of knowledge in relation to the use of Vernonia amygdalina. The methodology consists of conducting a semi-structured survey of herbalists in markets, on sites where medicinal plants are sold and in households. This methodology allowed us to identify 38 species of medicinal plants belonging to 20 families. The best represented species is Bridelia ferruginea (10) of the family Euphobiaceae. The Rubiaceae family is the most represented (16). The organ of the plant most frequently used in recipes is the root (47). Five hundred and fifty-two households (552) responded to our questions. 64% use the leaves of Vernonia amygdalina for nutrition against 36% for therapeutic use. 68% are supplied from distant fields, 13% from urban areas and 19% from market gardening sites. 35% say they have no information about its use in phytotherapy, 21% use it for intestinal ailments, 18% for the treatment of malaria, 13% for oral diseases, 12% for other pathologies. The frequency of use (four times a week) is best represented for nutrition and phytotherapy. In conclusion, Vernonia amygdalina is very little known in phytotherapy despite the various researches carried out on this plant. Researchers must promote medicinal plants that are very easy to grow in order to limit the offer to users of rare plants in danger of extinction.},
 year = {2020}
}

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