Asymptomatic Hepatitis C in Patient with Oral Lichen Planus: A Case Report

Suresh Kumar Sachdeva; Purnendu Rout; Debahuti Patnaik; Ashok Galav

doi:doi:10.11648/j.ijbecs.20170302.12

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Asymptomatic Hepatitis C in Patient with Oral Lichen Planus: A Case Report

Suresh Kumar Sachdeva, Purnendu Rout, Debahuti Patnaik, Ashok Galav

Published in International Journal of Biomedical Engineering and Clinical Science (Volume 3, Issue 2)

Received: 3 June 2017 Accepted: 22 June 2017 Published: 18 October 2017

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Abstract

Lichen planus (LP) is a chronic inflammatory condition that affects the oral mucous membrane/skin with a variety of clinical presentations. Oral Lichen Planus (OLP) is considered to be associated with numerous systemic conditions one of which includes hepatitis C virus (HCV) infection. The geographic variation of the hepatitis C prevalence proved to be an important factor influencing the statistical results of the studies analyzing the association of the oral plan lichen with the hepatitis C virus. LP patients have about a fivefold higher risk than the controls of being HCV seropositive, with geographic variability, being most prevalent in the region of Japan, Mediterranean countries and the USA. Treatment outcomes in patients with oral lichen planus associated with chronic hepatitis C virus are often unsatisfactory compared to patients suffering from idiopathic oral lichen planus. Also, the evolution of oral lesions is often fluctuating, with repeated periods of relapse according to the degree of liver function decompensation. Herewith, a case of oral lichen planus in a female patient is reported, which on investigation revealed hepatitis C antibodies.

Published in	International Journal of Biomedical Engineering and Clinical Science (Volume 3, Issue 2)
DOI	10.11648/j.ijbecs.20170302.12
Page(s)	14-17
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Female, Hepatitis C, Lichen Planus, Oral

References

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[2]	Gupta S, Jawanda MK. Oral lichen planus: An update on etiology, pathogenesis, clinical presentation, diagnosis and management. Indian J Dermatol. 2015; 60: 222-229.
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[4]	Sugerman PB, Savage NW, Walsh LJ, Zhao ZZ, Zhou XJ, Khan A, Seymour GJ, Bigby M. The pathogenesis of oral lichen planus. Crit Rev Oral Biol Med. 2002; 13: 350-365.
[5]	Machado AC, Sugaya NN, Migliari DA, Matthews RW. Oral lichen planus: Clinical aspects and management in fifty-two Brazilian patients. West Indian Med J. 2003; 52: 203-207.
[6]	White CP, Hirsch G, Patel S, Adams F, Peltekian KM. Complementary and alternative medicine use by patients chronically infected with hepatitis C virus. Can J Gastroenterol. 2007; 21: 589-595.
[7]	Harden D, Skelton H, Smith KJ. Lichen planus associated with hepatitis C virus: no viral transcripts are found in the lichen planus, and effective therapy for hepatitis C virus does not clear lichen planus. J Am Acad Dermatol. 2003; 49: 847-852.
[8]	Pilli M, Penna A, Zerbini A, Vescovi P, Manfredi M, Negro F, Carrozzo M, Mori C, Giuberti T, Ferrari C, Missale G. Oral lichen planus pathogenesis: a role for the HCV-specific cellular immune response. Hepatology. 2002; 36: 1446-1452.
[9]	Cacoub P, Comarmond C, Domont F, Savey L, Desbois AC, Saadoun D. Extrahepatic manifestations of chronic hepatitis C virus infection. Therapeutic Advances in Infectious Disease. 2016; 3: 3-14.
[10]	Ibrahim HA, Baddour MM, Morsi MG, Abdelkader AA. Should we routinely check for hepatitis B and C in patients with lichen planus or cutaneous vasculitis? East Mediterr Health J. 1999; 5: 71-78.
[11]	Harman M, Akdeniz S, Dursun M, et al. Lichen planus and hepatitis C virus infection: an epidemiologic study. Int J Clin Pract 2004; 58: 1118-1119.
[12]	Nagao Y, Sata M, Itoh K, et al. Quantitative analysis of HCV RNA and genotype in patients withchronic hepatitis C accompanied by oral lichen planus. Eur J Clin Invest 1996; 26: 495-498.
[13]	Figueiredo LC, Carrilho FJ, de Andrage HF, Migliari DA. Oral lichen planus and hepatitis C virus infection. Oral Dis 2002; 8: 42-46.
[14]	Mega H, Jiang WW, Takagi M. Immunohistochemical study of oral lichen planus associated with hepatitis C virus infection, oral lichenoid contact sensitivity reaction and idiopathic oral lichen planus. Oral Dis 2001; 7: 296-305.
[15]	Lazaro P, Olalquiaga J, Bartolome J, et al. Detection of hepatitis C virus RNA and core protein in keratinocytes from patients with cutaneous lichen planus and chronic hepatitis C. J Invest Dermatol2002; 119 (4): 798-803.
[16]	Klanrit P, Thongprasom K, Rojanawatsirivej S, et al. Hepatitis C virus infection in Thai patients with oral lichen planus. Oral Dis 2003; 9 (6): 292-7.
[17]	Beaird LM, Kahloon N, Franco J, Fairley JA. Incidence of hepatitis c in lichen planus. J Am Acad Dermatol. 2001; 44: 311-312.

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APA Style

Suresh Kumar Sachdeva, Purnendu Rout, Debahuti Patnaik, Ashok Galav. (2017). Asymptomatic Hepatitis C in Patient with Oral Lichen Planus: A Case Report. International Journal of Biomedical Engineering and Clinical Science, 3(2), 14-17. https://doi.org/10.11648/j.ijbecs.20170302.12

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ACS Style

Suresh Kumar Sachdeva; Purnendu Rout; Debahuti Patnaik; Ashok Galav. Asymptomatic Hepatitis C in Patient with Oral Lichen Planus: A Case Report. Int. J. Biomed. Eng. Clin. Sci. 2017, 3(2), 14-17. doi: 10.11648/j.ijbecs.20170302.12

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AMA Style

Suresh Kumar Sachdeva, Purnendu Rout, Debahuti Patnaik, Ashok Galav. Asymptomatic Hepatitis C in Patient with Oral Lichen Planus: A Case Report. Int J Biomed Eng Clin Sci. 2017;3(2):14-17. doi: 10.11648/j.ijbecs.20170302.12

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@article{10.11648/j.ijbecs.20170302.12,
  author = {Suresh Kumar Sachdeva and Purnendu Rout and Debahuti Patnaik and Ashok Galav},
  title = {Asymptomatic Hepatitis C in Patient with Oral Lichen Planus: A Case Report},
  journal = {International Journal of Biomedical Engineering and Clinical Science},
  volume = {3},
  number = {2},
  pages = {14-17},
  doi = {10.11648/j.ijbecs.20170302.12},
  url = {https://doi.org/10.11648/j.ijbecs.20170302.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbecs.20170302.12},
  abstract = {Lichen planus (LP) is a chronic inflammatory condition that affects the oral mucous membrane/skin with a variety of clinical presentations. Oral Lichen Planus (OLP) is considered to be associated with numerous systemic conditions one of which includes hepatitis C virus (HCV) infection. The geographic variation of the hepatitis C prevalence proved to be an important factor influencing the statistical results of the studies analyzing the association of the oral plan lichen with the hepatitis C virus. LP patients have about a fivefold higher risk than the controls of being HCV seropositive, with geographic variability, being most prevalent in the region of Japan, Mediterranean countries and the USA. Treatment outcomes in patients with oral lichen planus associated with chronic hepatitis C virus are often unsatisfactory compared to patients suffering from idiopathic oral lichen planus. Also, the evolution of oral lesions is often fluctuating, with repeated periods of relapse according to the degree of liver function decompensation. Herewith, a case of oral lichen planus in a female patient is reported, which on investigation revealed hepatitis C antibodies.},
 year = {2017}
}

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TY  - JOUR
T1  - Asymptomatic Hepatitis C in Patient with Oral Lichen Planus: A Case Report
AU  - Suresh Kumar Sachdeva
AU  - Purnendu Rout
AU  - Debahuti Patnaik
AU  - Ashok Galav
Y1  - 2017/10/18
PY  - 2017
N1  - https://doi.org/10.11648/j.ijbecs.20170302.12
DO  - 10.11648/j.ijbecs.20170302.12
T2  - International Journal of Biomedical Engineering and Clinical Science
JF  - International Journal of Biomedical Engineering and Clinical Science
JO  - International Journal of Biomedical Engineering and Clinical Science
SP  - 14
EP  - 17
PB  - Science Publishing Group
SN  - 2472-1301
UR  - https://doi.org/10.11648/j.ijbecs.20170302.12
AB  - Lichen planus (LP) is a chronic inflammatory condition that affects the oral mucous membrane/skin with a variety of clinical presentations. Oral Lichen Planus (OLP) is considered to be associated with numerous systemic conditions one of which includes hepatitis C virus (HCV) infection. The geographic variation of the hepatitis C prevalence proved to be an important factor influencing the statistical results of the studies analyzing the association of the oral plan lichen with the hepatitis C virus. LP patients have about a fivefold higher risk than the controls of being HCV seropositive, with geographic variability, being most prevalent in the region of Japan, Mediterranean countries and the USA. Treatment outcomes in patients with oral lichen planus associated with chronic hepatitis C virus are often unsatisfactory compared to patients suffering from idiopathic oral lichen planus. Also, the evolution of oral lesions is often fluctuating, with repeated periods of relapse according to the degree of liver function decompensation. Herewith, a case of oral lichen planus in a female patient is reported, which on investigation revealed hepatitis C antibodies.
VL  - 3
IS  - 2
ER  -

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Author Information

Suresh Kumar Sachdeva

Department of Oral Medicine and Radiology, Surendera Dental College & Research Institute, Sri Ganganagar, India
Purnendu Rout

Department of Oral Medicine and Radiology, Kalinga Institute of Dental Sciences, KIIT University, Bhubaneswar, India
Debahuti Patnaik

Department of Orthodontics, Kalinga Institute of Dental Sciences, KIIT University, Bhubaneswar, India
Ashok Galav

Department of Oral Medicine and Radiology, Tatya Saheb Kore Dental College & Research Centre, Kohlapur, India

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Plain Text BibTeX RIS

APA Style

Suresh Kumar Sachdeva, Purnendu Rout, Debahuti Patnaik, Ashok Galav. (2017). Asymptomatic Hepatitis C in Patient with Oral Lichen Planus: A Case Report. International Journal of Biomedical Engineering and Clinical Science, 3(2), 14-17. https://doi.org/10.11648/j.ijbecs.20170302.12

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ACS Style

Suresh Kumar Sachdeva; Purnendu Rout; Debahuti Patnaik; Ashok Galav. Asymptomatic Hepatitis C in Patient with Oral Lichen Planus: A Case Report. Int. J. Biomed. Eng. Clin. Sci. 2017, 3(2), 14-17. doi: 10.11648/j.ijbecs.20170302.12

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AMA Style

Suresh Kumar Sachdeva, Purnendu Rout, Debahuti Patnaik, Ashok Galav. Asymptomatic Hepatitis C in Patient with Oral Lichen Planus: A Case Report. Int J Biomed Eng Clin Sci. 2017;3(2):14-17. doi: 10.11648/j.ijbecs.20170302.12

Copy | Download

@article{10.11648/j.ijbecs.20170302.12,
  author = {Suresh Kumar Sachdeva and Purnendu Rout and Debahuti Patnaik and Ashok Galav},
  title = {Asymptomatic Hepatitis C in Patient with Oral Lichen Planus: A Case Report},
  journal = {International Journal of Biomedical Engineering and Clinical Science},
  volume = {3},
  number = {2},
  pages = {14-17},
  doi = {10.11648/j.ijbecs.20170302.12},
  url = {https://doi.org/10.11648/j.ijbecs.20170302.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbecs.20170302.12},
  abstract = {Lichen planus (LP) is a chronic inflammatory condition that affects the oral mucous membrane/skin with a variety of clinical presentations. Oral Lichen Planus (OLP) is considered to be associated with numerous systemic conditions one of which includes hepatitis C virus (HCV) infection. The geographic variation of the hepatitis C prevalence proved to be an important factor influencing the statistical results of the studies analyzing the association of the oral plan lichen with the hepatitis C virus. LP patients have about a fivefold higher risk than the controls of being HCV seropositive, with geographic variability, being most prevalent in the region of Japan, Mediterranean countries and the USA. Treatment outcomes in patients with oral lichen planus associated with chronic hepatitis C virus are often unsatisfactory compared to patients suffering from idiopathic oral lichen planus. Also, the evolution of oral lesions is often fluctuating, with repeated periods of relapse according to the degree of liver function decompensation. Herewith, a case of oral lichen planus in a female patient is reported, which on investigation revealed hepatitis C antibodies.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Asymptomatic Hepatitis C in Patient with Oral Lichen Planus: A Case Report
AU  - Suresh Kumar Sachdeva
AU  - Purnendu Rout
AU  - Debahuti Patnaik
AU  - Ashok Galav
Y1  - 2017/10/18
PY  - 2017
N1  - https://doi.org/10.11648/j.ijbecs.20170302.12
DO  - 10.11648/j.ijbecs.20170302.12
T2  - International Journal of Biomedical Engineering and Clinical Science
JF  - International Journal of Biomedical Engineering and Clinical Science
JO  - International Journal of Biomedical Engineering and Clinical Science
SP  - 14
EP  - 17
PB  - Science Publishing Group
SN  - 2472-1301
UR  - https://doi.org/10.11648/j.ijbecs.20170302.12
AB  - Lichen planus (LP) is a chronic inflammatory condition that affects the oral mucous membrane/skin with a variety of clinical presentations. Oral Lichen Planus (OLP) is considered to be associated with numerous systemic conditions one of which includes hepatitis C virus (HCV) infection. The geographic variation of the hepatitis C prevalence proved to be an important factor influencing the statistical results of the studies analyzing the association of the oral plan lichen with the hepatitis C virus. LP patients have about a fivefold higher risk than the controls of being HCV seropositive, with geographic variability, being most prevalent in the region of Japan, Mediterranean countries and the USA. Treatment outcomes in patients with oral lichen planus associated with chronic hepatitis C virus are often unsatisfactory compared to patients suffering from idiopathic oral lichen planus. Also, the evolution of oral lesions is often fluctuating, with repeated periods of relapse according to the degree of liver function decompensation. Herewith, a case of oral lichen planus in a female patient is reported, which on investigation revealed hepatitis C antibodies.
VL  - 3
IS  - 2
ER  -

Copy | Download