Comparative Study of Prolactin Levels in Acne and Non-Acne Individuals Among Students of College of Health Sciences, Nnamdi Azikiwe University, Nnewi, Nigeria

Emmanuel Okechukwu Chukwu; Odunukwe Juliet Ifeoma; Terkuma Chia; Ufearo Chibueze Stephen; Ugbor Godwin Onyedikachi

doi:doi:10.11648/j.ijbecs.20170304.11

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Comparative Study of Prolactin Levels in Acne and Non-Acne Individuals Among Students of College of Health Sciences, Nnamdi Azikiwe University, Nnewi, Nigeria

Emmanuel Okechukwu Chukwu, Odunukwe Juliet Ifeoma, Terkuma Chia, Ufearo Chibueze Stephen, Ugbor Godwin Onyedikachi

Published in International Journal of Biomedical Engineering and Clinical Science (Volume 3, Issue 4)

Received: 22 February 2017 Accepted: 21 March 2017 Published: 18 October 2017

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Abstract

Prolactin (PRL) is well recognized for its role(s) in mammary gland development and function as well as over three hundred non-lactational functions. However, androgens have a main role in acne pathogenesis and the interaction between prolactin and androgens generate the hypothesis of prolactin role in acne pathogenesis. Therefore a difference should exist in the prolactin hormone levels of acne individuals in comparison with non-acne individuals. The aim of this study was to make assessment and comparison of serum hormonal levels of prolactin in acne vulgaris individuals and non-acne individuals. In this cross-sectional case control study, serum levels of prolactin were collected and estimated in 60 subjects consisting of 30 males and 30 females each; of which 15 were the control group and 15, the test group in each category respectively. Also certain criteria’s were looked into such as subject’s age, state of health, menstrual patterns (for females) and much more. Data collected was analyzed using the Software Package for Social Sciences (SPSS). At the end of the experiment, the result showed no significant change (p<0.05), however mean serum prolactin levels were significantly high among the acne cases in both the males (12.26 ± 1.50) when compared to the control of males (8.80 ± 1.03), and also acne cases of the females (22.04 ± 4.59) when compared to the control of the females (12.92 ± 1.62) females. A non-significant change in the comparism of serum prolactin levels of acne subjects and non-acne subjects in both males and females may be as result of the small sample size used. However, more powerful studies are needed. An increase in the mean serum prolactin levels of acne subjects in both categories when compared to non-acne subjects indicates the contribution of prolactin in the pathogenesis of acne.

Published in	International Journal of Biomedical Engineering and Clinical Science (Volume 3, Issue 4)
DOI	10.11648/j.ijbecs.20170304.11
Page(s)	25-31
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Comparative, Study, Prolactin, Levels, Acne, Non-Acne, Individuals

References

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APA Style

Emmanuel Okechukwu Chukwu, Odunukwe Juliet Ifeoma, Terkuma Chia, Ufearo Chibueze Stephen, Ugbor Godwin Onyedikachi. (2017). Comparative Study of Prolactin Levels in Acne and Non-Acne Individuals Among Students of College of Health Sciences, Nnamdi Azikiwe University, Nnewi, Nigeria. International Journal of Biomedical Engineering and Clinical Science, 3(4), 25-31. https://doi.org/10.11648/j.ijbecs.20170304.11

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ACS Style

Emmanuel Okechukwu Chukwu; Odunukwe Juliet Ifeoma; Terkuma Chia; Ufearo Chibueze Stephen; Ugbor Godwin Onyedikachi. Comparative Study of Prolactin Levels in Acne and Non-Acne Individuals Among Students of College of Health Sciences, Nnamdi Azikiwe University, Nnewi, Nigeria. Int. J. Biomed. Eng. Clin. Sci. 2017, 3(4), 25-31. doi: 10.11648/j.ijbecs.20170304.11

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AMA Style

Emmanuel Okechukwu Chukwu, Odunukwe Juliet Ifeoma, Terkuma Chia, Ufearo Chibueze Stephen, Ugbor Godwin Onyedikachi. Comparative Study of Prolactin Levels in Acne and Non-Acne Individuals Among Students of College of Health Sciences, Nnamdi Azikiwe University, Nnewi, Nigeria. Int J Biomed Eng Clin Sci. 2017;3(4):25-31. doi: 10.11648/j.ijbecs.20170304.11

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@article{10.11648/j.ijbecs.20170304.11,
  author = {Emmanuel Okechukwu Chukwu and Odunukwe Juliet Ifeoma and Terkuma Chia and Ufearo Chibueze Stephen and Ugbor Godwin Onyedikachi},
  title = {Comparative Study of Prolactin Levels in Acne and Non-Acne Individuals Among Students of College of Health Sciences, Nnamdi Azikiwe University, Nnewi, Nigeria},
  journal = {International Journal of Biomedical Engineering and Clinical Science},
  volume = {3},
  number = {4},
  pages = {25-31},
  doi = {10.11648/j.ijbecs.20170304.11},
  url = {https://doi.org/10.11648/j.ijbecs.20170304.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbecs.20170304.11},
  abstract = {Prolactin (PRL) is well recognized for its role(s) in mammary gland development and function as well as over three hundred non-lactational functions. However, androgens have a main role in acne pathogenesis and the interaction between prolactin and androgens generate the hypothesis of prolactin role in acne pathogenesis. Therefore a difference should exist in the prolactin hormone levels of acne individuals in comparison with non-acne individuals. The aim of this study was to make assessment and comparison of serum hormonal levels of prolactin in acne vulgaris individuals and non-acne individuals. In this cross-sectional case control study, serum levels of prolactin were collected and estimated in 60 subjects consisting of 30 males and 30 females each; of which 15 were the control group and 15, the test group in each category respectively. Also certain criteria’s were looked into such as subject’s age, state of health, menstrual patterns (for females) and much more. Data collected was analyzed using the Software Package for Social Sciences (SPSS). At the end of the experiment, the result showed no significant change (p<0.05), however mean serum prolactin levels were significantly high among the acne cases in both the males (12.26 ± 1.50) when compared to the control of males (8.80 ± 1.03), and also acne cases of the females (22.04 ± 4.59) when compared to the control of the females (12.92 ± 1.62) females. A non-significant change in the comparism of serum prolactin levels of acne subjects and non-acne subjects in both males and females may be as result of the small sample size used. However, more powerful studies are needed. An increase in the mean serum prolactin levels of acne subjects in both categories when compared to non-acne subjects indicates the contribution of prolactin in the pathogenesis of acne.},
 year = {2017}
}

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TY  - JOUR
T1  - Comparative Study of Prolactin Levels in Acne and Non-Acne Individuals Among Students of College of Health Sciences, Nnamdi Azikiwe University, Nnewi, Nigeria
AU  - Emmanuel Okechukwu Chukwu
AU  - Odunukwe Juliet Ifeoma
AU  - Terkuma Chia
AU  - Ufearo Chibueze Stephen
AU  - Ugbor Godwin Onyedikachi
Y1  - 2017/10/18
PY  - 2017
N1  - https://doi.org/10.11648/j.ijbecs.20170304.11
DO  - 10.11648/j.ijbecs.20170304.11
T2  - International Journal of Biomedical Engineering and Clinical Science
JF  - International Journal of Biomedical Engineering and Clinical Science
JO  - International Journal of Biomedical Engineering and Clinical Science
SP  - 25
EP  - 31
PB  - Science Publishing Group
SN  - 2472-1301
UR  - https://doi.org/10.11648/j.ijbecs.20170304.11
AB  - Prolactin (PRL) is well recognized for its role(s) in mammary gland development and function as well as over three hundred non-lactational functions. However, androgens have a main role in acne pathogenesis and the interaction between prolactin and androgens generate the hypothesis of prolactin role in acne pathogenesis. Therefore a difference should exist in the prolactin hormone levels of acne individuals in comparison with non-acne individuals. The aim of this study was to make assessment and comparison of serum hormonal levels of prolactin in acne vulgaris individuals and non-acne individuals. In this cross-sectional case control study, serum levels of prolactin were collected and estimated in 60 subjects consisting of 30 males and 30 females each; of which 15 were the control group and 15, the test group in each category respectively. Also certain criteria’s were looked into such as subject’s age, state of health, menstrual patterns (for females) and much more. Data collected was analyzed using the Software Package for Social Sciences (SPSS). At the end of the experiment, the result showed no significant change (p<0.05), however mean serum prolactin levels were significantly high among the acne cases in both the males (12.26 ± 1.50) when compared to the control of males (8.80 ± 1.03), and also acne cases of the females (22.04 ± 4.59) when compared to the control of the females (12.92 ± 1.62) females. A non-significant change in the comparism of serum prolactin levels of acne subjects and non-acne subjects in both males and females may be as result of the small sample size used. However, more powerful studies are needed. An increase in the mean serum prolactin levels of acne subjects in both categories when compared to non-acne subjects indicates the contribution of prolactin in the pathogenesis of acne.
VL  - 3
IS  - 4
ER  -

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Author Information

Emmanuel Okechukwu Chukwu

School of Nursing Mkar, Gboko, Nigeria
Odunukwe Juliet Ifeoma

School of Nursing Mkar, Gboko, Nigeria
Terkuma Chia

School of Nursing Mkar, Gboko, Nigeria
Ufearo Chibueze Stephen

Department of Physiology, College of Health Sciences, Nnamdi Azikiwe University, Nnewi, Nigeria
Ugbor Godwin Onyedikachi

School of Midwifery Mkar, Gboko, Nigeria

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Emmanuel Okechukwu Chukwu, Odunukwe Juliet Ifeoma, Terkuma Chia, Ufearo Chibueze Stephen, Ugbor Godwin Onyedikachi. (2017). Comparative Study of Prolactin Levels in Acne and Non-Acne Individuals Among Students of College of Health Sciences, Nnamdi Azikiwe University, Nnewi, Nigeria. International Journal of Biomedical Engineering and Clinical Science, 3(4), 25-31. https://doi.org/10.11648/j.ijbecs.20170304.11

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ACS Style

Emmanuel Okechukwu Chukwu; Odunukwe Juliet Ifeoma; Terkuma Chia; Ufearo Chibueze Stephen; Ugbor Godwin Onyedikachi. Comparative Study of Prolactin Levels in Acne and Non-Acne Individuals Among Students of College of Health Sciences, Nnamdi Azikiwe University, Nnewi, Nigeria. Int. J. Biomed. Eng. Clin. Sci. 2017, 3(4), 25-31. doi: 10.11648/j.ijbecs.20170304.11

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AMA Style

Emmanuel Okechukwu Chukwu, Odunukwe Juliet Ifeoma, Terkuma Chia, Ufearo Chibueze Stephen, Ugbor Godwin Onyedikachi. Comparative Study of Prolactin Levels in Acne and Non-Acne Individuals Among Students of College of Health Sciences, Nnamdi Azikiwe University, Nnewi, Nigeria. Int J Biomed Eng Clin Sci. 2017;3(4):25-31. doi: 10.11648/j.ijbecs.20170304.11

Copy | Download

@article{10.11648/j.ijbecs.20170304.11,
  author = {Emmanuel Okechukwu Chukwu and Odunukwe Juliet Ifeoma and Terkuma Chia and Ufearo Chibueze Stephen and Ugbor Godwin Onyedikachi},
  title = {Comparative Study of Prolactin Levels in Acne and Non-Acne Individuals Among Students of College of Health Sciences, Nnamdi Azikiwe University, Nnewi, Nigeria},
  journal = {International Journal of Biomedical Engineering and Clinical Science},
  volume = {3},
  number = {4},
  pages = {25-31},
  doi = {10.11648/j.ijbecs.20170304.11},
  url = {https://doi.org/10.11648/j.ijbecs.20170304.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbecs.20170304.11},
  abstract = {Prolactin (PRL) is well recognized for its role(s) in mammary gland development and function as well as over three hundred non-lactational functions. However, androgens have a main role in acne pathogenesis and the interaction between prolactin and androgens generate the hypothesis of prolactin role in acne pathogenesis. Therefore a difference should exist in the prolactin hormone levels of acne individuals in comparison with non-acne individuals. The aim of this study was to make assessment and comparison of serum hormonal levels of prolactin in acne vulgaris individuals and non-acne individuals. In this cross-sectional case control study, serum levels of prolactin were collected and estimated in 60 subjects consisting of 30 males and 30 females each; of which 15 were the control group and 15, the test group in each category respectively. Also certain criteria’s were looked into such as subject’s age, state of health, menstrual patterns (for females) and much more. Data collected was analyzed using the Software Package for Social Sciences (SPSS). At the end of the experiment, the result showed no significant change (p<0.05), however mean serum prolactin levels were significantly high among the acne cases in both the males (12.26 ± 1.50) when compared to the control of males (8.80 ± 1.03), and also acne cases of the females (22.04 ± 4.59) when compared to the control of the females (12.92 ± 1.62) females. A non-significant change in the comparism of serum prolactin levels of acne subjects and non-acne subjects in both males and females may be as result of the small sample size used. However, more powerful studies are needed. An increase in the mean serum prolactin levels of acne subjects in both categories when compared to non-acne subjects indicates the contribution of prolactin in the pathogenesis of acne.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Comparative Study of Prolactin Levels in Acne and Non-Acne Individuals Among Students of College of Health Sciences, Nnamdi Azikiwe University, Nnewi, Nigeria
AU  - Emmanuel Okechukwu Chukwu
AU  - Odunukwe Juliet Ifeoma
AU  - Terkuma Chia
AU  - Ufearo Chibueze Stephen
AU  - Ugbor Godwin Onyedikachi
Y1  - 2017/10/18
PY  - 2017
N1  - https://doi.org/10.11648/j.ijbecs.20170304.11
DO  - 10.11648/j.ijbecs.20170304.11
T2  - International Journal of Biomedical Engineering and Clinical Science
JF  - International Journal of Biomedical Engineering and Clinical Science
JO  - International Journal of Biomedical Engineering and Clinical Science
SP  - 25
EP  - 31
PB  - Science Publishing Group
SN  - 2472-1301
UR  - https://doi.org/10.11648/j.ijbecs.20170304.11
AB  - Prolactin (PRL) is well recognized for its role(s) in mammary gland development and function as well as over three hundred non-lactational functions. However, androgens have a main role in acne pathogenesis and the interaction between prolactin and androgens generate the hypothesis of prolactin role in acne pathogenesis. Therefore a difference should exist in the prolactin hormone levels of acne individuals in comparison with non-acne individuals. The aim of this study was to make assessment and comparison of serum hormonal levels of prolactin in acne vulgaris individuals and non-acne individuals. In this cross-sectional case control study, serum levels of prolactin were collected and estimated in 60 subjects consisting of 30 males and 30 females each; of which 15 were the control group and 15, the test group in each category respectively. Also certain criteria’s were looked into such as subject’s age, state of health, menstrual patterns (for females) and much more. Data collected was analyzed using the Software Package for Social Sciences (SPSS). At the end of the experiment, the result showed no significant change (p<0.05), however mean serum prolactin levels were significantly high among the acne cases in both the males (12.26 ± 1.50) when compared to the control of males (8.80 ± 1.03), and also acne cases of the females (22.04 ± 4.59) when compared to the control of the females (12.92 ± 1.62) females. A non-significant change in the comparism of serum prolactin levels of acne subjects and non-acne subjects in both males and females may be as result of the small sample size used. However, more powerful studies are needed. An increase in the mean serum prolactin levels of acne subjects in both categories when compared to non-acne subjects indicates the contribution of prolactin in the pathogenesis of acne.
VL  - 3
IS  - 4
ER  -

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