Assessment of Immunomodulatory Activity of the Biofield Energy Treated Novel Herbomineral Formulation After Oral Administration in Female Sprague Dawley Rats
International Journal of Biomedical Engineering and Clinical Science
Volume 3, Issue 6, November 2017, Pages: 90-99
Received: Oct. 30, 2017; Accepted: Nov. 14, 2017; Published: Nov. 30, 2017
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Authors
Mahendra Kumar Trivedi, Trivedi Global, Inc., Henderson, Nevada, USA
Alice Branton, Trivedi Global, Inc., Henderson, Nevada, USA
Dahryn Trivedi, Trivedi Global, Inc., Henderson, Nevada, USA
Gopal Nayak, Trivedi Global, Inc., Henderson, Nevada, USA
Cathryn Dawn Nykvist, Trivedi Global, Inc., Henderson, Nevada, USA
Celine Lavelle, Trivedi Global, Inc., Henderson, Nevada, USA
Daniel Paul Przybylski, Trivedi Global, Inc., Henderson, Nevada, USA
Dianne Heather Vincent, Trivedi Global, Inc., Henderson, Nevada, USA
Dorothy Felger, Trivedi Global, Inc., Henderson, Nevada, USA
Douglas Jay Konersman, Trivedi Global, Inc., Henderson, Nevada, USA
Elizabeth Ann Feeney, Trivedi Global, Inc., Henderson, Nevada, USA
Jay Anthony Prague, Trivedi Global, Inc., Henderson, Nevada, USA
Joanne Lydia Starodub, Trivedi Global, Inc., Henderson, Nevada, USA
Karan Rasdan, Trivedi Global, Inc., Henderson, Nevada, USA
Karen Mie Strassman, Trivedi Global, Inc., Henderson, Nevada, USA
Leonid Soboleff, Trivedi Global, Inc., Henderson, Nevada, USA
Maire Mayne, Trivedi Global, Inc., Henderson, Nevada, USA
Mary M. Keesee, Trivedi Global, Inc., Henderson, Nevada, USA
Padmanabha Narayana Pillai, Trivedi Global, Inc., Henderson, Nevada, USA
Pamela Clarkson Ansley, Trivedi Global, Inc., Henderson, Nevada, USA
Ronald David Schmitz, Trivedi Global, Inc., Henderson, Nevada, USA
Sharyn Marie Sodomora, Trivedi Global, Inc., Henderson, Nevada, USA
Sambhu Charan Mondal, Trivedi Science Research Laboratory Pvt. Ltd., Bhopal, India
Snehasis Jana, Trivedi Science Research Laboratory Pvt. Ltd., Bhopal, India
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Abstract
The use of an herbomineral formulation in the healthcare sector for different chronic diseases is gaining popularity due to its fewer side-effects, high safety profile, and cost effectiveness. A new proprietary herbomineral formulation was formulated, consisting of four essential ingredients viz. herbal (ashwagandha root extract) and minerals (zinc chloride, magnesium gluconate, and sodium selenate). The objective of this study was to evaluate the immunomodulatory effect of the Biofield Energy Treated test formulation on female Sprague Dawley (SD) rats. The test formulation was divided into two parts; one was represented as control, while the other part was treated with the Biofield Energy Healing Treatment remotely by renowned Biofield Energy Healers (The Trivedi Effect®) and defined as the Biofield Energy Treated formulation. The effect of the test formulation was monitored using humoral immune response, delayed type hypersensitivity, hematology, biochemistry, relative organ weight, and histopathology. The primary hemagglutination (HA) antibody titre level was significantly (p≤0.05) increased by 185.88% in the Biofield Energy Treated group (G3); while 41.18% increased in the untreated test formulation group (G4) as compared to the disease control group (G2). The secondary HA titre was significantly increased by 540% (p≤0.001) and 166.7% in the G3 and G4 groups, respectively as compared to the G2 group. The secondary HA titre was also increased significantly (p≤0.05) by 193% in the Biofield Energy Treated group per se at day -15 (G6), as compared to the G2 group. The paw volume data showed an alteration in the G3 and G6 groups as compared to the G2 group. The platelet count was significantly increased by 11.16% and 8.69% in the G3 and G4 groups, respectively as compared to the G2 group. The magnesium level was increased by 9.31% in the G3 group as compared to the G2 group. The uric acid was significantly reduced by 23.88% in the G3 group; while it was increased by 17.47% in the G4 group as compared to the G2 group. Since, the relative organ weight and histopathological findings did not produce any signs of toxicity as compared to the normal control group (G1). These data suggested that the Biofield Energy Treated herbomineral formulation was found to be safe and showed better immunomodulatory response as compared to the untreated formulation. Thus, it is assumed that the Biofield Energy Treated herbomineral formulation could be better and more useful to boost-up the immune system in healthy human and patients.
Keywords
Biofield Energy Healing Treatment, The Trivedi Effect®, Immunomodulation, Humoral Immune Response, Herbomineral Formulation, Hematology, Stress Management, Anti-aging
To cite this article
Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Cathryn Dawn Nykvist, Celine Lavelle, Daniel Paul Przybylski, Dianne Heather Vincent, Dorothy Felger, Douglas Jay Konersman, Elizabeth Ann Feeney, Jay Anthony Prague, Joanne Lydia Starodub, Karan Rasdan, Karen Mie Strassman, Leonid Soboleff, Maire Mayne, Mary M. Keesee, Padmanabha Narayana Pillai, Pamela Clarkson Ansley, Ronald David Schmitz, Sharyn Marie Sodomora, Sambhu Charan Mondal, Snehasis Jana, Assessment of Immunomodulatory Activity of the Biofield Energy Treated Novel Herbomineral Formulation After Oral Administration in Female Sprague Dawley Rats, International Journal of Biomedical Engineering and Clinical Science. Vol. 3, No. 6, 2017, pp. 90-99. doi: 10.11648/j.ijbecs.20170306.14
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Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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