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The Role of Predictors Parameters in the Management Policy and Outcome of Congenital Diaphragmatic Hernia with the Lack of Resources in Single Pediatric Surgery Unit

Received: 3 April 2017    Accepted: 21 April 2017    Published: 8 January 2018
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Abstract

Background: The objective of this study is to have the interest to know how far the present study underscores the improved survival rate for patients with CDH and risk factors affecting the outcome with the lack of many essential facilities. Our inquiries: shall we proceed without ECMO and related resources! Patients and Methods: The records of patients admitted with CDH to the pediatric surgery unit at the Maternity and Children Teaching Hospital Al Qadisiya, Iraq, from January 1, 2005, to the end of December 2014 were retrospectively reviewed. Reports obtained about operative findings, respiratory complications, although attempts were made to confirm a suspected diagnosis of pulmonary hypertension using echocardiography. Despite that, the permissive hypercapnia and ECMO were not practiced during the study period (these facilities still unavailable in our unit), we considering that the studied patients suspected to have such facilities according to ECMO protocol. All presentation factors with some of the predictive parameters are studied and taken as background to analyze our study. Statistical analyses performed using the Statistical Package for Social Sciences (SPSS) version 20 software and Excel 2016. Independent t-test used for analysis of normally distributed continuous data. A p-value of <.0001 considered statistically significant. Results: Thirty-one patients (26 neonates) were managed at our unit with an overall survival 19 of the total patients 73.07% and 14 (53.84%) of the neonates. Male presented 18 (69.23%) out of the total. Birth weight in grams (range) 3100 (2100 to 4390). Apgar (mean) at 5 min. after delivery (range) 6.2±2.1. At the level of Prenatal factors, chest to head circumference ratio <0.80 presented as the most important risk factor (Odd ratio 27.50, 95% confidence intervals (CI) upper 289.13 and p-value <.0001). At birth factors, associated major anomalies (Odd ratio 3.50, 95% CI upper 17.89 and p-value <.0001) formed risk parameter. Overall, both favorable and unfavorable factors had significant correlation and predictive effects on both survival and mortality groups respectively. Conclusion: A composite of prognostic and predictive parameters, however, organize our workup and can magnify our management future policy despite that, these prognostic indicators measure different aspects of CDH.

Published in International Journal of Biomedical Engineering and Clinical Science (Volume 3, Issue 6)
DOI 10.11648/j.ijbecs.20170306.17
Page(s) 110-118
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Predictive Parameters, Management Policy, Congenital Diaphragmatic Hernia

References
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    Mohammed Joudi Aboud. (2018). The Role of Predictors Parameters in the Management Policy and Outcome of Congenital Diaphragmatic Hernia with the Lack of Resources in Single Pediatric Surgery Unit. International Journal of Biomedical Engineering and Clinical Science, 3(6), 110-118. https://doi.org/10.11648/j.ijbecs.20170306.17

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    Mohammed Joudi Aboud. The Role of Predictors Parameters in the Management Policy and Outcome of Congenital Diaphragmatic Hernia with the Lack of Resources in Single Pediatric Surgery Unit. Int. J. Biomed. Eng. Clin. Sci. 2018, 3(6), 110-118. doi: 10.11648/j.ijbecs.20170306.17

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    AMA Style

    Mohammed Joudi Aboud. The Role of Predictors Parameters in the Management Policy and Outcome of Congenital Diaphragmatic Hernia with the Lack of Resources in Single Pediatric Surgery Unit. Int J Biomed Eng Clin Sci. 2018;3(6):110-118. doi: 10.11648/j.ijbecs.20170306.17

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  • @article{10.11648/j.ijbecs.20170306.17,
      author = {Mohammed Joudi Aboud},
      title = {The Role of Predictors Parameters in the Management Policy and Outcome of Congenital Diaphragmatic Hernia with the Lack of Resources in Single Pediatric Surgery Unit},
      journal = {International Journal of Biomedical Engineering and Clinical Science},
      volume = {3},
      number = {6},
      pages = {110-118},
      doi = {10.11648/j.ijbecs.20170306.17},
      url = {https://doi.org/10.11648/j.ijbecs.20170306.17},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbecs.20170306.17},
      abstract = {Background: The objective of this study is to have the interest to know how far the present study underscores the improved survival rate for patients with CDH and risk factors affecting the outcome with the lack of many essential facilities. Our inquiries: shall we proceed without ECMO and related resources! Patients and Methods: The records of patients admitted with CDH to the pediatric surgery unit at the Maternity and Children Teaching Hospital Al Qadisiya, Iraq, from January 1, 2005, to the end of December 2014 were retrospectively reviewed. Reports obtained about operative findings, respiratory complications, although attempts were made to confirm a suspected diagnosis of pulmonary hypertension using echocardiography. Despite that, the permissive hypercapnia and ECMO were not practiced during the study period (these facilities still unavailable in our unit), we considering that the studied patients suspected to have such facilities according to ECMO protocol. All presentation factors with some of the predictive parameters are studied and taken as background to analyze our study. Statistical analyses performed using the Statistical Package for Social Sciences (SPSS) version 20 software and Excel 2016. Independent t-test used for analysis of normally distributed continuous data. A p-value of <.0001 considered statistically significant. Results: Thirty-one patients (26 neonates) were managed at our unit with an overall survival 19 of the total patients 73.07% and 14 (53.84%) of the neonates. Male presented 18 (69.23%) out of the total. Birth weight in grams (range) 3100 (2100 to 4390). Apgar (mean) at 5 min. after delivery (range) 6.2±2.1. At the level of Prenatal factors, chest to head circumference ratio <0.80 presented as the most important risk factor (Odd ratio 27.50, 95% confidence intervals (CI) upper 289.13 and p-value <.0001). At birth factors, associated major anomalies (Odd ratio 3.50, 95% CI upper 17.89 and p-value <.0001) formed risk parameter. Overall, both favorable and unfavorable factors had significant correlation and predictive effects on both survival and mortality groups respectively. Conclusion: A composite of prognostic and predictive parameters, however, organize our workup and can magnify our management future policy despite that, these prognostic indicators measure different aspects of CDH.},
     year = {2018}
    }
    

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  • TY  - JOUR
    T1  - The Role of Predictors Parameters in the Management Policy and Outcome of Congenital Diaphragmatic Hernia with the Lack of Resources in Single Pediatric Surgery Unit
    AU  - Mohammed Joudi Aboud
    Y1  - 2018/01/08
    PY  - 2018
    N1  - https://doi.org/10.11648/j.ijbecs.20170306.17
    DO  - 10.11648/j.ijbecs.20170306.17
    T2  - International Journal of Biomedical Engineering and Clinical Science
    JF  - International Journal of Biomedical Engineering and Clinical Science
    JO  - International Journal of Biomedical Engineering and Clinical Science
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    EP  - 118
    PB  - Science Publishing Group
    SN  - 2472-1301
    UR  - https://doi.org/10.11648/j.ijbecs.20170306.17
    AB  - Background: The objective of this study is to have the interest to know how far the present study underscores the improved survival rate for patients with CDH and risk factors affecting the outcome with the lack of many essential facilities. Our inquiries: shall we proceed without ECMO and related resources! Patients and Methods: The records of patients admitted with CDH to the pediatric surgery unit at the Maternity and Children Teaching Hospital Al Qadisiya, Iraq, from January 1, 2005, to the end of December 2014 were retrospectively reviewed. Reports obtained about operative findings, respiratory complications, although attempts were made to confirm a suspected diagnosis of pulmonary hypertension using echocardiography. Despite that, the permissive hypercapnia and ECMO were not practiced during the study period (these facilities still unavailable in our unit), we considering that the studied patients suspected to have such facilities according to ECMO protocol. All presentation factors with some of the predictive parameters are studied and taken as background to analyze our study. Statistical analyses performed using the Statistical Package for Social Sciences (SPSS) version 20 software and Excel 2016. Independent t-test used for analysis of normally distributed continuous data. A p-value of <.0001 considered statistically significant. Results: Thirty-one patients (26 neonates) were managed at our unit with an overall survival 19 of the total patients 73.07% and 14 (53.84%) of the neonates. Male presented 18 (69.23%) out of the total. Birth weight in grams (range) 3100 (2100 to 4390). Apgar (mean) at 5 min. after delivery (range) 6.2±2.1. At the level of Prenatal factors, chest to head circumference ratio <0.80 presented as the most important risk factor (Odd ratio 27.50, 95% confidence intervals (CI) upper 289.13 and p-value <.0001). At birth factors, associated major anomalies (Odd ratio 3.50, 95% CI upper 17.89 and p-value <.0001) formed risk parameter. Overall, both favorable and unfavorable factors had significant correlation and predictive effects on both survival and mortality groups respectively. Conclusion: A composite of prognostic and predictive parameters, however, organize our workup and can magnify our management future policy despite that, these prognostic indicators measure different aspects of CDH.
    VL  - 3
    IS  - 6
    ER  - 

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  • Pediatric Surgery Unit, the Maternity and Child Teaching Hospital, Al Qadisiya, Iraq

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