Study on Antiviral Activities of Glycyrrhizin

Changchao Huan; Chunqin Chen; Weiyin Xu; Tingting Guo; Haochun Pan; Song Gao

doi:doi:10.11648/j.ijbecs.20200604.11

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Study on Antiviral Activities of Glycyrrhizin

Changchao Huan, Chunqin Chen, Weiyin Xu, Tingting Guo, Haochun Pan, Song Gao

Published in International Journal of Biomedical Engineering and Clinical Science (Volume 6, Issue 4)

Received: 16 October 2020 Accepted: 2 November 2020 Published: 9 November 2020

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Abstract

Licorice has been a common Chinese medicine for thousands of years, which has good medicinal value and nutritional value. Is widely apply to traditional Chinese medicine. Many studies have shown that licorice contains more than 20 triterpenoids and nearly 300 flavonoids. According to the literature, licorice has many activities such as antibacterial, antiviral, antioxidant, and anticancer. It not only directly inactivates the virus, but also inhibits its adsorption. However, glycyrrhizin, glycyrrhetinic acid, glycyrrhiza polysaccharide and glycyrrhiza flavonoids are the main components of licorice which possess antiviral and antimicrobial activities. Among them, glycyrrhizin has many pharmacological activities, such as antiviral, anti-inflammatory, anti-tumor, antibacterial and many other activities. This paper provides a summary of antiviral activities of glycyrrhizin. This active ingredients and possible mechanisms are summarized in detail. The results showed that glycyrrhizin was widely used in antiviral field, but its material basis and mechanism of action were not perfect and unified. A large number of literatures about glycyrrhizin anti-virus were reviewed and analyzed, and it was suggested that more different ways should be adopted to study it, so as to provide a broader theoretical basis for developing new antivirus drugs of glycyrrhizin. It is hoped that this review will be helpful to further study the potential therapeutic effect of glycyrrhizin as an antiviral drug.

Published in	International Journal of Biomedical Engineering and Clinical Science (Volume 6, Issue 4)
DOI	10.11648/j.ijbecs.20200604.11
Page(s)	68-70
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Glycyrrhizin, Antiviral, Chinese Medicine

References

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APA Style

Changchao Huan, Chunqin Chen, Weiyin Xu, Tingting Guo, Haochun Pan, et al. (2020). Study on Antiviral Activities of Glycyrrhizin. International Journal of Biomedical Engineering and Clinical Science, 6(4), 68-70. https://doi.org/10.11648/j.ijbecs.20200604.11

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ACS Style

Changchao Huan; Chunqin Chen; Weiyin Xu; Tingting Guo; Haochun Pan, et al. Study on Antiviral Activities of Glycyrrhizin. Int. J. Biomed. Eng. Clin. Sci. 2020, 6(4), 68-70. doi: 10.11648/j.ijbecs.20200604.11

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AMA Style

Changchao Huan, Chunqin Chen, Weiyin Xu, Tingting Guo, Haochun Pan, et al. Study on Antiviral Activities of Glycyrrhizin. Int J Biomed Eng Clin Sci. 2020;6(4):68-70. doi: 10.11648/j.ijbecs.20200604.11

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@article{10.11648/j.ijbecs.20200604.11,
  author = {Changchao Huan and Chunqin Chen and Weiyin Xu and Tingting Guo and Haochun Pan and Song Gao},
  title = {Study on Antiviral Activities of Glycyrrhizin},
  journal = {International Journal of Biomedical Engineering and Clinical Science},
  volume = {6},
  number = {4},
  pages = {68-70},
  doi = {10.11648/j.ijbecs.20200604.11},
  url = {https://doi.org/10.11648/j.ijbecs.20200604.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbecs.20200604.11},
  abstract = {Licorice has been a common Chinese medicine for thousands of years, which has good medicinal value and nutritional value. Is widely apply to traditional Chinese medicine. Many studies have shown that licorice contains more than 20 triterpenoids and nearly 300 flavonoids. According to the literature, licorice has many activities such as antibacterial, antiviral, antioxidant, and anticancer. It not only directly inactivates the virus, but also inhibits its adsorption. However, glycyrrhizin, glycyrrhetinic acid, glycyrrhiza polysaccharide and glycyrrhiza flavonoids are the main components of licorice which possess antiviral and antimicrobial activities. Among them, glycyrrhizin has many pharmacological activities, such as antiviral, anti-inflammatory, anti-tumor, antibacterial and many other activities. This paper provides a summary of antiviral activities of glycyrrhizin. This active ingredients and possible mechanisms are summarized in detail. The results showed that glycyrrhizin was widely used in antiviral field, but its material basis and mechanism of action were not perfect and unified. A large number of literatures about glycyrrhizin anti-virus were reviewed and analyzed, and it was suggested that more different ways should be adopted to study it, so as to provide a broader theoretical basis for developing new antivirus drugs of glycyrrhizin. It is hoped that this review will be helpful to further study the potential therapeutic effect of glycyrrhizin as an antiviral drug.},
 year = {2020}
}

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TY - JOUR
T1 - Study on Antiviral Activities of Glycyrrhizin
AU - Changchao Huan
AU - Chunqin Chen
AU - Weiyin Xu
AU - Tingting Guo
AU - Haochun Pan
AU - Song Gao
Y1 - 2020/11/09
PY - 2020
N1 - https://doi.org/10.11648/j.ijbecs.20200604.11
DO - 10.11648/j.ijbecs.20200604.11
T2 - International Journal of Biomedical Engineering and Clinical Science
JF - International Journal of Biomedical Engineering and Clinical Science
JO - International Journal of Biomedical Engineering and Clinical Science
SP - 68
EP - 70
PB - Science Publishing Group
SN - 2472-1301
UR - https://doi.org/10.11648/j.ijbecs.20200604.11
AB - Licorice has been a common Chinese medicine for thousands of years, which has good medicinal value and nutritional value. Is widely apply to traditional Chinese medicine. Many studies have shown that licorice contains more than 20 triterpenoids and nearly 300 flavonoids. According to the literature, licorice has many activities such as antibacterial, antiviral, antioxidant, and anticancer. It not only directly inactivates the virus, but also inhibits its adsorption. However, glycyrrhizin, glycyrrhetinic acid, glycyrrhiza polysaccharide and glycyrrhiza flavonoids are the main components of licorice which possess antiviral and antimicrobial activities. Among them, glycyrrhizin has many pharmacological activities, such as antiviral, anti-inflammatory, anti-tumor, antibacterial and many other activities. This paper provides a summary of antiviral activities of glycyrrhizin. This active ingredients and possible mechanisms are summarized in detail. The results showed that glycyrrhizin was widely used in antiviral field, but its material basis and mechanism of action were not perfect and unified. A large number of literatures about glycyrrhizin anti-virus were reviewed and analyzed, and it was suggested that more different ways should be adopted to study it, so as to provide a broader theoretical basis for developing new antivirus drugs of glycyrrhizin. It is hoped that this review will be helpful to further study the potential therapeutic effect of glycyrrhizin as an antiviral drug.
VL - 6
IS - 4
ER -

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Author Information

Changchao Huan

Institutes of Agricultural Science and Technology Development, College of Veterinary Medicine, Yangzhou University, Yangzhou, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China; Key Laboratory of Avian Bioproduct Development, Ministry of Agriculture and Rural Affairs, Yangzhou, China
Chunqin Chen

Institutes of Agricultural Science and Technology Development, College of Veterinary Medicine, Yangzhou University, Yangzhou, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China; Key Laboratory of Avian Bioproduct Development, Ministry of Agriculture and Rural Affairs, Yangzhou, China
Weiyin Xu

Institutes of Agricultural Science and Technology Development, College of Veterinary Medicine, Yangzhou University, Yangzhou, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China; Key Laboratory of Avian Bioproduct Development, Ministry of Agriculture and Rural Affairs, Yangzhou, China
Tingting Guo

College of Medicine, Yangzhou University, Yangzhou, China
Haochun Pan

Institutes of Agricultural Science and Technology Development, College of Veterinary Medicine, Yangzhou University, Yangzhou, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China; Key Laboratory of Avian Bioproduct Development, Ministry of Agriculture and Rural Affairs, Yangzhou, China
Song Gao

Institutes of Agricultural Science and Technology Development, College of Veterinary Medicine, Yangzhou University, Yangzhou, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, China; Key Laboratory of Avian Bioproduct Development, Ministry of Agriculture and Rural Affairs, Yangzhou, China

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APA Style

Changchao Huan, Chunqin Chen, Weiyin Xu, Tingting Guo, Haochun Pan, et al. (2020). Study on Antiviral Activities of Glycyrrhizin. International Journal of Biomedical Engineering and Clinical Science, 6(4), 68-70. https://doi.org/10.11648/j.ijbecs.20200604.11

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ACS Style

Changchao Huan; Chunqin Chen; Weiyin Xu; Tingting Guo; Haochun Pan, et al. Study on Antiviral Activities of Glycyrrhizin. Int. J. Biomed. Eng. Clin. Sci. 2020, 6(4), 68-70. doi: 10.11648/j.ijbecs.20200604.11

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AMA Style

Changchao Huan, Chunqin Chen, Weiyin Xu, Tingting Guo, Haochun Pan, et al. Study on Antiviral Activities of Glycyrrhizin. Int J Biomed Eng Clin Sci. 2020;6(4):68-70. doi: 10.11648/j.ijbecs.20200604.11

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@article{10.11648/j.ijbecs.20200604.11,
  author = {Changchao Huan and Chunqin Chen and Weiyin Xu and Tingting Guo and Haochun Pan and Song Gao},
  title = {Study on Antiviral Activities of Glycyrrhizin},
  journal = {International Journal of Biomedical Engineering and Clinical Science},
  volume = {6},
  number = {4},
  pages = {68-70},
  doi = {10.11648/j.ijbecs.20200604.11},
  url = {https://doi.org/10.11648/j.ijbecs.20200604.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbecs.20200604.11},
  abstract = {Licorice has been a common Chinese medicine for thousands of years, which has good medicinal value and nutritional value. Is widely apply to traditional Chinese medicine. Many studies have shown that licorice contains more than 20 triterpenoids and nearly 300 flavonoids. According to the literature, licorice has many activities such as antibacterial, antiviral, antioxidant, and anticancer. It not only directly inactivates the virus, but also inhibits its adsorption. However, glycyrrhizin, glycyrrhetinic acid, glycyrrhiza polysaccharide and glycyrrhiza flavonoids are the main components of licorice which possess antiviral and antimicrobial activities. Among them, glycyrrhizin has many pharmacological activities, such as antiviral, anti-inflammatory, anti-tumor, antibacterial and many other activities. This paper provides a summary of antiviral activities of glycyrrhizin. This active ingredients and possible mechanisms are summarized in detail. The results showed that glycyrrhizin was widely used in antiviral field, but its material basis and mechanism of action were not perfect and unified. A large number of literatures about glycyrrhizin anti-virus were reviewed and analyzed, and it was suggested that more different ways should be adopted to study it, so as to provide a broader theoretical basis for developing new antivirus drugs of glycyrrhizin. It is hoped that this review will be helpful to further study the potential therapeutic effect of glycyrrhizin as an antiviral drug.},
 year = {2020}
}

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