Band 3 Protein Function and Oxidative Stress in Erythrocytes from Systemic Sclerosis Patients with Interstitial Lung Disease

Rossana Morabito; Alessia Remigante; Gianluca Bagnato; William Neal Roberts; Davide Sciortino; Tommaso D’Angelo; Filippo Iannelli; Dario Iannelli; Francesca Cordova; Mariateresa Cirillo; Giuseppina La Spada; Angela Marino

doi:doi:10.11648/j.ejcbs.20170304.12

Band 3 Protein Function and Oxidative Stress in Erythrocytes from Systemic Sclerosis Patients with Interstitial Lung Disease

Rossana Morabito, Alessia Remigante, Gianluca Bagnato, William Neal Roberts, Davide Sciortino, Tommaso D’Angelo, Filippo Iannelli, Dario Iannelli, Francesca Cordova, Mariateresa Cirillo, Giuseppina La Spada, Angela Marino

Published in European Journal of Clinical and Biomedical Sciences (Volume 3, Issue 4)

Received: 16 May 2017 Accepted: 28 June 2017 Published: 27 July 2017

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Abstract

A link between reactive oxygen species (ROS) and Systemic Sclerosis (SSc) development has been already described, along with an oxidative stress-induced reduction of anion exchange capability through Band 3 protein. On this basis, blood from SSc patients has been collected to measure the rate constant for SO₄⁼ uptake, which is an index for anion exchange capability through Band 3 protein. This parameter was significantly reduced in SSc patients, with or without Interstitial Lung Disease, a complication of SSc. As a reduced Band 3 protein function was observed in SSc patients with either low or high levels of malonildialdehyde (MDA), the end product of lipoperoxidation, anion exchange through erythrocytes membrane may be not univocally related to oxidative stress and, what is more, can be considered as a sensitive tool to monitor SSc development.

Published in	European Journal of Clinical and Biomedical Sciences (Volume 3, Issue 4)
DOI	10.11648/j.ejcbs.20170304.12
Page(s)	80-84
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Band 3 Protein, Erythrocytes, Interstitial Lung Disease, Oxidative Stress, Systemic Sclerosis

References

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APA Style

Rossana Morabito, Alessia Remigante, Gianluca Bagnato, William Neal Roberts, Davide Sciortino, et al. (2017). Band 3 Protein Function and Oxidative Stress in Erythrocytes from Systemic Sclerosis Patients with Interstitial Lung Disease. European Journal of Clinical and Biomedical Sciences, 3(4), 80-84. https://doi.org/10.11648/j.ejcbs.20170304.12

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ACS Style

Rossana Morabito; Alessia Remigante; Gianluca Bagnato; William Neal Roberts; Davide Sciortino, et al. Band 3 Protein Function and Oxidative Stress in Erythrocytes from Systemic Sclerosis Patients with Interstitial Lung Disease. Eur. J. Clin. Biomed. Sci. 2017, 3(4), 80-84. doi: 10.11648/j.ejcbs.20170304.12

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AMA Style

Rossana Morabito, Alessia Remigante, Gianluca Bagnato, William Neal Roberts, Davide Sciortino, et al. Band 3 Protein Function and Oxidative Stress in Erythrocytes from Systemic Sclerosis Patients with Interstitial Lung Disease. Eur J Clin Biomed Sci. 2017;3(4):80-84. doi: 10.11648/j.ejcbs.20170304.12

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@article{10.11648/j.ejcbs.20170304.12,
  author = {Rossana Morabito and Alessia Remigante and Gianluca Bagnato and William Neal Roberts and Davide Sciortino and Tommaso D’Angelo and Filippo Iannelli and Dario Iannelli and Francesca Cordova and Mariateresa Cirillo and Giuseppina La Spada and Angela Marino},
  title = {Band 3 Protein Function and Oxidative Stress in Erythrocytes from Systemic Sclerosis Patients with Interstitial Lung Disease},
  journal = {European Journal of Clinical and Biomedical Sciences},
  volume = {3},
  number = {4},
  pages = {80-84},
  doi = {10.11648/j.ejcbs.20170304.12},
  url = {https://doi.org/10.11648/j.ejcbs.20170304.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejcbs.20170304.12},
  abstract = {A link between reactive oxygen species (ROS) and Systemic Sclerosis (SSc) development has been already described, along with an oxidative stress-induced reduction of anion exchange capability through Band 3 protein. On this basis, blood from SSc patients has been collected to measure the rate constant for SO4= uptake, which is an index for anion exchange capability through Band 3 protein. This parameter was significantly reduced in SSc patients, with or without Interstitial Lung Disease, a complication of SSc. As a reduced Band 3 protein function was observed in SSc patients with either low or high levels of malonildialdehyde (MDA), the end product of lipoperoxidation, anion exchange through erythrocytes membrane may be not univocally related to oxidative stress and, what is more, can be considered as a sensitive tool to monitor SSc development.},
 year = {2017}
}

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TY  - JOUR
T1  - Band 3 Protein Function and Oxidative Stress in Erythrocytes from Systemic Sclerosis Patients with Interstitial Lung Disease
AU  - Rossana Morabito
AU  - Alessia Remigante
AU  - Gianluca Bagnato
AU  - William Neal Roberts
AU  - Davide Sciortino
AU  - Tommaso D’Angelo
AU  - Filippo Iannelli
AU  - Dario Iannelli
AU  - Francesca Cordova
AU  - Mariateresa Cirillo
AU  - Giuseppina La Spada
AU  - Angela Marino
Y1  - 2017/07/27
PY  - 2017
N1  - https://doi.org/10.11648/j.ejcbs.20170304.12
DO  - 10.11648/j.ejcbs.20170304.12
T2  - European Journal of Clinical and Biomedical Sciences
JF  - European Journal of Clinical and Biomedical Sciences
JO  - European Journal of Clinical and Biomedical Sciences
SP  - 80
EP  - 84
PB  - Science Publishing Group
SN  - 2575-5005
UR  - https://doi.org/10.11648/j.ejcbs.20170304.12
AB  - A link between reactive oxygen species (ROS) and Systemic Sclerosis (SSc) development has been already described, along with an oxidative stress-induced reduction of anion exchange capability through Band 3 protein. On this basis, blood from SSc patients has been collected to measure the rate constant for SO4= uptake, which is an index for anion exchange capability through Band 3 protein. This parameter was significantly reduced in SSc patients, with or without Interstitial Lung Disease, a complication of SSc. As a reduced Band 3 protein function was observed in SSc patients with either low or high levels of malonildialdehyde (MDA), the end product of lipoperoxidation, anion exchange through erythrocytes membrane may be not univocally related to oxidative stress and, what is more, can be considered as a sensitive tool to monitor SSc development.
VL  - 3
IS  - 4
ER  -

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Author Information

Rossana Morabito

Department Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy
Alessia Remigante

Department Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy
Gianluca Bagnato

Department Clinical and Experimental Medicine, University of Messina, Messina, Italy
William Neal Roberts

Department Medicine, University of Louisville, Kentucky, US
Davide Sciortino

Department Clinical and Experimental Medicine, University of Messina, Messina, Italy
Tommaso D’Angelo

Department Biomedical Sciences and Morphological and Functional Imaging, University of Messina, Messina, Italy
Filippo Iannelli

Department Clinical and Experimental Medicine, University of Messina, Messina, Italy
Dario Iannelli

Department Clinical and Experimental Medicine, University of Messina, Messina, Italy
Francesca Cordova

Department Clinical and Experimental Medicine, University of Messina, Messina, Italy
Mariateresa Cirillo

Department Clinical and Experimental Medicine, University of Messina, Messina, Italy
Giuseppina La Spada

Department Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy
Angela Marino

Department Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy

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APA Style

Rossana Morabito, Alessia Remigante, Gianluca Bagnato, William Neal Roberts, Davide Sciortino, et al. (2017). Band 3 Protein Function and Oxidative Stress in Erythrocytes from Systemic Sclerosis Patients with Interstitial Lung Disease. European Journal of Clinical and Biomedical Sciences, 3(4), 80-84. https://doi.org/10.11648/j.ejcbs.20170304.12

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ACS Style

Rossana Morabito; Alessia Remigante; Gianluca Bagnato; William Neal Roberts; Davide Sciortino, et al. Band 3 Protein Function and Oxidative Stress in Erythrocytes from Systemic Sclerosis Patients with Interstitial Lung Disease. Eur. J. Clin. Biomed. Sci. 2017, 3(4), 80-84. doi: 10.11648/j.ejcbs.20170304.12

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AMA Style

Rossana Morabito, Alessia Remigante, Gianluca Bagnato, William Neal Roberts, Davide Sciortino, et al. Band 3 Protein Function and Oxidative Stress in Erythrocytes from Systemic Sclerosis Patients with Interstitial Lung Disease. Eur J Clin Biomed Sci. 2017;3(4):80-84. doi: 10.11648/j.ejcbs.20170304.12

Copy | Download

@article{10.11648/j.ejcbs.20170304.12,
  author = {Rossana Morabito and Alessia Remigante and Gianluca Bagnato and William Neal Roberts and Davide Sciortino and Tommaso D’Angelo and Filippo Iannelli and Dario Iannelli and Francesca Cordova and Mariateresa Cirillo and Giuseppina La Spada and Angela Marino},
  title = {Band 3 Protein Function and Oxidative Stress in Erythrocytes from Systemic Sclerosis Patients with Interstitial Lung Disease},
  journal = {European Journal of Clinical and Biomedical Sciences},
  volume = {3},
  number = {4},
  pages = {80-84},
  doi = {10.11648/j.ejcbs.20170304.12},
  url = {https://doi.org/10.11648/j.ejcbs.20170304.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejcbs.20170304.12},
  abstract = {A link between reactive oxygen species (ROS) and Systemic Sclerosis (SSc) development has been already described, along with an oxidative stress-induced reduction of anion exchange capability through Band 3 protein. On this basis, blood from SSc patients has been collected to measure the rate constant for SO4= uptake, which is an index for anion exchange capability through Band 3 protein. This parameter was significantly reduced in SSc patients, with or without Interstitial Lung Disease, a complication of SSc. As a reduced Band 3 protein function was observed in SSc patients with either low or high levels of malonildialdehyde (MDA), the end product of lipoperoxidation, anion exchange through erythrocytes membrane may be not univocally related to oxidative stress and, what is more, can be considered as a sensitive tool to monitor SSc development.},
 year = {2017}
}

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TY  - JOUR
T1  - Band 3 Protein Function and Oxidative Stress in Erythrocytes from Systemic Sclerosis Patients with Interstitial Lung Disease
AU  - Rossana Morabito
AU  - Alessia Remigante
AU  - Gianluca Bagnato
AU  - William Neal Roberts
AU  - Davide Sciortino
AU  - Tommaso D’Angelo
AU  - Filippo Iannelli
AU  - Dario Iannelli
AU  - Francesca Cordova
AU  - Mariateresa Cirillo
AU  - Giuseppina La Spada
AU  - Angela Marino
Y1  - 2017/07/27
PY  - 2017
N1  - https://doi.org/10.11648/j.ejcbs.20170304.12
DO  - 10.11648/j.ejcbs.20170304.12
T2  - European Journal of Clinical and Biomedical Sciences
JF  - European Journal of Clinical and Biomedical Sciences
JO  - European Journal of Clinical and Biomedical Sciences
SP  - 80
EP  - 84
PB  - Science Publishing Group
SN  - 2575-5005
UR  - https://doi.org/10.11648/j.ejcbs.20170304.12
AB  - A link between reactive oxygen species (ROS) and Systemic Sclerosis (SSc) development has been already described, along with an oxidative stress-induced reduction of anion exchange capability through Band 3 protein. On this basis, blood from SSc patients has been collected to measure the rate constant for SO4= uptake, which is an index for anion exchange capability through Band 3 protein. This parameter was significantly reduced in SSc patients, with or without Interstitial Lung Disease, a complication of SSc. As a reduced Band 3 protein function was observed in SSc patients with either low or high levels of malonildialdehyde (MDA), the end product of lipoperoxidation, anion exchange through erythrocytes membrane may be not univocally related to oxidative stress and, what is more, can be considered as a sensitive tool to monitor SSc development.
VL  - 3
IS  - 4
ER  -

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