Solitary Extramedullary Plasmacytoma of the Trachea: A Case Report
International Journal of Cardiovascular and Thoracic Surgery
Volume 2, Issue 1, May 2016, Pages: 5-8
Received: Dec. 30, 2015;
Accepted: Feb. 29, 2016;
Published: May 5, 2016
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Antonello Cuttitta, IRCCS “Casa Sollievo della Sofferenza” Hospital, Unit of General Surgery 2nd and Thoracic Surgery, Viale Cappuccini 1, San Giovanni Rotondo, Foggia, Italy
Antonio Tancredi, Azienda Sanitaria Locale di Foggia, “San Camillo De Lellis” Hospital, Unit of General Surgery, Via Isonzo, Manfredonia, Foggia, Italy
Roberto Scaramuzzi, Second University of Naples, Unit of Thoracic Surgery, Piazza Miraglia 2, Naples, NA, Italy
Antonietta Falcone, IRCCS “Casa Sollievo della Sofferenza” Hospital, Unit of Haematology, Viale Cappuccini 1, San Giovanni Rotondo, Foggia, Italy
Gerardo Scaramuzzi, IRCCS “Casa Sollievo della Sofferenza” Hospital, Unit of General Surgery 2nd and Thoracic Surgery, Viale Cappuccini 1, San Giovanni Rotondo, Foggia, Italy
Marco Taurchini, IRCCS “Casa Sollievo della Sofferenza” Hospital, Unit of General Surgery 2nd and Thoracic Surgery, Viale Cappuccini 1, San Giovanni Rotondo, Foggia, Italy
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The extramedullary plasmacytomas is a plasma cell tumour arising outside the bone marrow and constitutes around 4 % of all plasma cell neoplasms. The Extramedullary Plasmacytoma of the Trachea (EPT) is an extremely rare condition and presents as a tracheal expanding mass. The most common symptoms consist of coughing, dyspnoea, voice change, stridor and expiratory wheezing. The diagnosis is done by computed tomography, bronchoscopy and histological examination which demonstrates neoplastic monoclonal plasma cells expressing specific antigens. The treatment of the EPT remains still speculative, current options are radiotherapy or surgery alone and surgery followed by radiotherapy. The adjuvant chemotherapy is considered only in case of relapse or systemic spread. The prognosis is comforting: the complete remission occurs in 60 % of cases, the recurrence in 22 %, the progression to multiple myeloma in 16 %. We report the case of a 51-year-old female affected by EPT and treated with the removal of the first four tracheal rings and subsequent PAD chemotherapy (bortezomib, adriamycin and dexamethasone). Although the stage of the tumour was early, we decided to administer chemotherapy conceiving it as a preventive systemic treatment.
Tracheal Tumours, Tracheal Resection, Extramedullary Plasmacytoma, Airway Obstruction
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Solitary Extramedullary Plasmacytoma of the Trachea: A Case Report, International Journal of Cardiovascular and Thoracic Surgery.
Vol. 2, No. 1,
2016, pp. 5-8.
Copyright © 2016 Authors retain the copyright of this article.
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