A Case Report: A Rare Case of Multiple Chest Wall Schwannomas Associated with Uterine Leiomyoma and Infertility
International Journal of Cardiovascular and Thoracic Surgery
Volume 4, Issue 1, January 2018, Pages: 1-4
Received: Nov. 12, 2017; Accepted: Dec. 14, 2017; Published: Jan. 8, 2018
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Authors
Kawkabani Nadine, Cardiac Surgery Anesthesia Department, Saint Georges Hospital University Medical Center, Beirut, Lebanon
Darwish Rula, Cardiac Surgery Anesthesia Department, Saint Georges Hospital University Medical Center, Beirut, Lebanon
Boustros Omar, Cardio-Thoracic Surgery Department, Saint Georges Hospital University Medical Center-University of Balamand, Beirut, Lebanon
Bejjani Simon, Cardio-Thoracic Surgery Department, Saint Georges Hospital University Medical Center-University of Balamand, Beirut, Lebanon
El Achkar Nancy, General Anesthesia Department, Saint Georges Hospital University Medical Center-University of Balamand, Beirut, Lebanon
Abou Khalil Bassam, Cardio-Thoracic Surgery Department, Saint Georges Hospital University Medical Center, Beirut, Lebanon
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Abstract
Schwannomatosis is a tumor predisposition syndrome characterized by development of multiple schwannomas that are slow-growing encapsulating neurogenic tumors. It is a recurrent condition and patients lack usually the classic cutaneous stigmata, vestibular schwannomas or brain parenchyma tumors. Many papers have incriminated the mutation of the SMARCB1 gene in this disease which has been also observed in cases of uterine leiomyoma. This report describes a rare case of multiple chest wall schwannomas associated to a uterine fibroma. A genetic study done did not show any SMARCB1 gene mutation. Subsequently a further genetic counselling and a whole exome sequencing were recommended especially that the patient underwent many trials of failed IVF and two miscarriages despite resection of all the tumors.
Keywords
Schwannomatosis, Leiomyoma, Infertility, Genetic Mutation
To cite this article
Kawkabani Nadine, Darwish Rula, Boustros Omar, Bejjani Simon, El Achkar Nancy, Abou Khalil Bassam, A Case Report: A Rare Case of Multiple Chest Wall Schwannomas Associated with Uterine Leiomyoma and Infertility, International Journal of Cardiovascular and Thoracic Surgery. Vol. 4, No. 1, 2018, pp. 1-4. doi: 10.11648/j.ijcts.20180401.11
Copyright
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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