Platelet Parameters and Variations With Age Amongst Elderly Nepalese Presenting in BPKIHS, Dharan Research Project (March 29-April 25)
Biomedical Sciences
Volume 5, Issue 4, December 2019, Pages: 67-70
Received: Jun. 21, 2019; Accepted: Jul. 18, 2019; Published: Nov. 25, 2019
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Indira Ojha, Department of Pathology, BP Koirala Institute of Health Sciences, Dharan, Nepal
Seema Oli, Department of Pathology, BP Koirala Institute of Health Sciences, Dharan, Nepal
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Platelets are derived from megakaryocytes and help in hemostasis and produce growth factors. Platelet count and MPV are parameters used in various conditions and vary with age and sex. The purpose of this study was to compare platelet count and MPV of healthy young with healthy elderly and calculate normal range of platelet count and to find relationship of platelet count and MPV with age and sex. Prospective study was done on 202 people visiting hematology department of BPKIHS, 100 as cases and 102 as controls, after obtaining ethical clearance. Only the consenting individuals and individual meeting inclusion criteria were included in the study. Blood sample was drawn in EDTA vial and Platelet counts and MPV was measured by 5 part hematology analyzer. Results showed that platelet count is higher in females and young individuals while platelet volume is higher in elderly. Study shows that there is insignificant difference between platelet count and MPV between elderly population and young control. Thus, from this prospective study conducted on 202 people we concluded that there is a rise in MPV with age and decrease in platelet count. However, the difference is insignificant and does not mandate separate reference range for various age groups.
Platelets, Platelet Count, Mean Platelet Volume
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Indira Ojha, Seema Oli, Platelet Parameters and Variations With Age Amongst Elderly Nepalese Presenting in BPKIHS, Dharan Research Project (March 29-April 25), Biomedical Sciences. Vol. 5, No. 4, 2019, pp. 67-70. doi: 10.11648/
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