Investigation of Treatment Regimen of the Genital Warts Using Various Chemotherapeutic Agents
Biomedical Sciences
Volume 6, Issue 1, March 2020, Pages: 1-4
Received: Oct. 28, 2019; Accepted: Jan. 3, 2020; Published: Jan. 21, 2020
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Arsalan Khan, Livestock Research & Development Station, Paharpur, Dera Ismail Khan, Pakistan
Muhammad Jamil, Arid Zone Research Centre, Pakistan Agriculture Research Council, Dera Ismail Khan, Pakistan
Rida Naz, District Headquarter Teaching Hospital, Dera Ismail Khan, Pakistan
Ayesha Humayun, Department of Clinical Studies, Faculty of Veterinary and Animal Sciences, Arid Agriculture University, Rawalpindi, Pakistan
Safi Ullah, Livestock Research & Development Station, Paharpur, Dera Ismail Khan, Pakistan
Ghulam Jelani, Department of Veterinary and Animal Sciences, University of Agriculture, Dera Ismail Khan, Pakistan
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Genital warts are the most commonly sexually transmitted viral infection of human beings caused by Human Papillomavirus, infecting both male as well as female sexes. The disease is clinically characterized by the appearance of external warts on the genital organs viz penis, scrotum, vulva, anus and perineal area. The present study was designed for the investigation of chemotherapeutic agents for the successful treatment/removal of lesions of genital warts in terms of recovery of patients and clearance percentage of genital organs from the warts. For this purpose, a total of 12 patients infected with genital warts were selected and randomly distributed into four different groups, each group comprising 03 patients. Group A was treated using locally available wart removal preparation Dewart® (Verrugon, Milk Acid), Group B was treated using Podophyllotoxin 15-25%, procured from chemical suppliers, Group C was treated using locally available Duofilm™ (Salicylic Acid 16.7% w/v, Lactic Acid 16.6% w/v) and Group D served as negative control. The results of the current study revealed that the standard and most effective treatment of the genital warts is found to be Podophyllotoxin @15-25%, which showed 100% recovery of the patients and 100% clearance of their genital areas from the stubborn warts. However, Duofilm™ was also found effective, because all the patients were recovered and 80% warts were cleared off from their genitalia, but after few weeks, the lesions re-appeared in the patients treated with Duofilm™. Also the warts did not go off with the local brands of Dewart® nor spontaneously recovered.
Clearance Percentage, Dewart®, Duofilm™, Genital Warts, Podophyllotoxin
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Arsalan Khan, Muhammad Jamil, Rida Naz, Ayesha Humayun, Safi Ullah, Ghulam Jelani, Investigation of Treatment Regimen of the Genital Warts Using Various Chemotherapeutic Agents, Biomedical Sciences. Vol. 6, No. 1, 2020, pp. 1-4. doi: 10.11648/
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