Haematological Derrangement Due to P. falciparum Infection in Patients of Selected Health Centres in Ardo-Kola Local Government Area, Taraba State
Biomedical Sciences
Volume 6, Issue 3, September 2020, Pages: 67-73
Received: Jul. 18, 2020; Accepted: Aug. 19, 2020; Published: Sep. 19, 2020
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Authors
Elkanah Obadiah Sambo, Department of Biological Sciences, Taraba State University, Jalingo, Nigeria
Obiorah Sylvester Chibuzor, Department of Laboratory Services, Federal Medical Centre, Jalingo, Nigeria
Onyeuku Okechukwu Chinwe, Department of Laboratory Services, Taraba State Specialist Hospital, Jalingo, Nigeria
Elkanah Deborah Sambo, Department of Biological Sciences, Taraba State University, Jalingo, Nigeria
Egeonu Stephen Ugoeze, Department of Laboratory Services, Federal Medical Centre, Jalingo, Nigeria
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Abstract
Malaria infection is one of the most common disease of public health importance afflicting millions of people in sub-Saharan Africa. This study investigated haematological derrangement among malaria infected and non-infected patients attending some Primary Health Centres in Ardo-Kola LGA, Taraba State, Nigeria. 585 blood samples were collected and examined for Plasmodium falciparum infection. Packed Cell Volume (PCV) was done by microhaematocrit and Erythrocyte Sedimentation Rate (ESR) using Westergen methods. The overall result showed a prevalence of ESR by Westergern method. It was found that malaria with low intensity of parasitaemia infection, 217 (37.09%) was more than medium and high intensity of parasitaemia with no significant difference (χ2=9.34; P≥0.05). The mean value of haematological parameters of parasitized subjects were 0.29 for PCV and 124.3655 for platelets which were significantly lower than those of non-parasitized subjects, PCV=0.4577 and Platelets=198.7698 respectively. Erythrocyte Sedimentation Rate (ESR) was higher (33.0852) in parasitized subjects than non-parasitized (20.0504). The result of this study could be useful in identification of high-risk malaria population. This will target intervention and assessment of impact based on changes in haematological parameters associated with P. falciparum infection. Futhermore, preventive strategies like chemoprophylaxis, provision of iron supplementation and insecticide treated nets could be employed in the study area to curb the upsurge in transmission.
Keywords
Haematological, Packed, Cell, Volume, Sedimentation
To cite this article
Elkanah Obadiah Sambo, Obiorah Sylvester Chibuzor, Onyeuku Okechukwu Chinwe, Elkanah Deborah Sambo, Egeonu Stephen Ugoeze, Haematological Derrangement Due to P. falciparum Infection in Patients of Selected Health Centres in Ardo-Kola Local Government Area, Taraba State, Biomedical Sciences. Vol. 6, No. 3, 2020, pp. 67-73. doi: 10.11648/j.bs.20200603.15
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Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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