Prevalence of Opportunistic Intestinal Protozoan Infection Among HIV/AIDS Patients in Jalingo Metropolis
Volume 6, Issue 3, September 2020, Pages: 74-78
Received: Jul. 18, 2020;
Accepted: Aug. 19, 2020;
Published: Sep. 19, 2020
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Onyeuku Okechukwu Chinwe, Department of Laboratory Services, Taraba State Specialist Hospital, Jalingo, Nigeria
Elkanah Obadiah Sambo, Department of Biological Sciences, Taraba State University, Jalingo, Nigeria
Obiorah Sylvester Chibuzor, Department of Laboratory Services, Federal Medical Centre, Jalingo, Nigeria
Elkanah Deborah Sambo, Department of Biological Sciences, Taraba State University, Jalingo, Nigeria
Egeonu Stephen Ugoeze, Department of Laboratory Services, Federal Medical Centre, Jalingo, Nigeria
Opportunistic protozoans parasitic infection occur frequently in individuals with weakened immune system including people with HIV/AIDS. The study sought to determine the prevalence of opportunistic intestinal protozoan infection in HIV/AIDS patients in Jalingo metropolis. The procedure of wet mount technique and faecal concentration techniques processed the faeces collected. The CD4+ count of patients were determined using the Partee Cyflow Counter, which determines the percentage of CD4+ cells of individuals. A total of eight hundred and fifty (850) faecal samples were collected from sero-positive and sero-negative HIV/AIDS persons in Jalingo metropolis. Out of the 850 subjects 650 (76.47%) were sero-positive while 200 (23.53%) were sero-negative (Control). The sero-positive subjects showed higher prevalence of 118 (18.15%) of opportunistic parasitic protozoan infection according to the following hospital locations: Government House, 12 (25.71%); Ummah Clinic, 8 (21.82%); Taraba State Specialist Hospital, 50 (18.18%) and Federal Medical Centre, 38 (15.20%). The prevalence was higher among female positives, 68 (l9.60%) than the male, 50 (16.50%) with no significant difference (p>0.05). The infection based on age groups revealed that the age group 10-15 years had the highest prevalence of 27 (48.21%) while the age group 41-45 years had the least prevalence of 2 (2.63%). Subjects involved in farming had higher prevalence 30 (46.15%) while the least was found among those of trading/business, 33 (13.86%) with no significant difference in infection (p>0.05). C. parvum had the highest prevalence, 46 (24.46%) among the sero-positive individuals while E. coli the highest among sero-negative, 9 (60.00%). It is recommended that clinicians caring for HIV/AIDS patients should request for routine stool examination for the specific diagnosis of opportunistic intestinal parasites infections.
Onyeuku Okechukwu Chinwe,
Elkanah Obadiah Sambo,
Obiorah Sylvester Chibuzor,
Elkanah Deborah Sambo,
Egeonu Stephen Ugoeze,
Prevalence of Opportunistic Intestinal Protozoan Infection Among HIV/AIDS Patients in Jalingo Metropolis, Biomedical Sciences.
Vol. 6, No. 3,
2020, pp. 74-78.
Obateru, O. A., Bojuwoye, B. J., Olokoba, A. B., Fadeyi, A. F., Olokoba, L. B. Prevalence of intestinal parasites in newly diagnosed HIV/AIDS patients in Ilorin, Nigeria. Alexandria Journal of Medicine, 2017; 53 (2): 111-116.
Ryan, K. J. and Ray, C. G. Sherris Medical Microbiology. 4th ed. McGraw Hill, 2004. pp. 733-738.
Gupta, K., Bala, M., Deb, M., Muralidhar, S. and Sharma, D. K. Prevalence of intestinal parasitic infections in HIV -infected individuals and their relationship with immune status. Indian Journal of Medical Microbiology, 2013; 31: 161-165.
National Agency for the Control of AIDS. Report on prevalence of HIV/AIDS in Nigeria-National Agency For The Control of HIV/AIDS, 2015; Pg 1129-1178.
Cheesbrough M. District laboratory practice in tropical countries. New York-Cambridge Press. Part1, 2nd Edition, 2012; 249-258.
Alemu G, Alelign D, Abossie A. Prevalence of Opportunistic Intestinal Parasites and Associated Factors among HIV Patients while Receiving ART at Arba Minch Hospital in Southern Ethiopia: A Cross-sectional Study. Ethiop J Health Sci. 2018; 28 (2): 147-156. doi: 10.4314/ejhs.v28i2.6.
Barcelos Natane Barbosa, Silva Lorena de Freitas e, Dias Regyane Ferreira Guimarães, Menezes Filho Hélio Ranes de, Rodrigues Rosângela Maria. Opportunistic and non-opportunistic intestinal parasites in HIV/ AIDS patients in relation to their clinical and epidemiological status in a specialized medical service in Goiás, Brazil. Rev. Inst. Med. trop. S. Paulo [Internet]. 2018 [cited 2020 Aug 18]; 60: e13. Available from: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652018005000206&lng=en. Epub Mar 08, 2018. https: //doi.org/10.1590/s1678-9946201860013.
Akinbo F O, Anate P J, Akinbo D B, Omoregie R, Okoosi S, Abdulsalami A, Isah B. Risk factors of intestinal parasitic infections among human immunodeficiency virus-infected patients on highly active antiretroviral therapy. Port Harcourt Med J, 2017; 11: 15-20.
Teklay, G., Haftom, K., Abebaw, A. G. Intestinal parasites among HIV/AIDS patients attending University of Gondar Hospital, northwest Ethiopia. Ethiop. J. Health Dev. 2019; 33 (2): 64-72.
Bokore A, Korme B, Bayisa G. Determinants of anti-retroviral regimen changes among HIV/AIDS patients of east and west Wollega zone health institutions, Oromia region, west Ethiopia: a cross-sectional study. BMC Pharmacol Toxicol 2018; 19 (1): 28.
Gebre B, Alemayehu T, Girma M, Ayalew F, Tadesse BT, Shemelis T. Cryptosporidiosis And Other Intestinal Parasitic Infections And Concomitant Threats Among HIV-Infected Children In Southern Ethiopia Receiving First-Line Antiretroviral Therapy. HIV AIDS (Auckl). 2019; 11: 299-306. Published 2019 Nov 15. doi: 10.2147/HIV.S215417.
Awofala AA, Ogundele OE. HIV epidemiology in Nigeria. Saudi J Biol Sci. 2016. doi: 10.1016/j.sjbs.2016.03.006.
Jegede FE, Oyeyi TI, Abdulrahman SA, Mbah HA, Badru T, Agbakwuru C et al. Effect of HIV and malaria parasites co-infection on immune-hematological profiles among patients attending anti-retroviral treatment (ART) clinic in Infectious Disease Hospital Kano, Nigeria. PloS One. 2017; 12 (3): e0174233.
Wang ZD, Liu Q, Liu HH. Prevalence of Cryptosporidium, microsporidia and Isospora infection in HIV-infected people: a global systematic review and meta-analysis. Parasites & Vectors. 2018 Jan; 11 (1): 28. DOI: 10.1186/s13071-017-2558-x.
Ahmadpour E, Safarpour H, Xiao L, Zarean M, Hatam-Nahavandi K, Barac A, Picot S, Rahimi MT, Rubino S, Mahami-Oskouei M, Spotin A, Nami S, Baghi HB. Cryptosporidiosis in HIV-positive patients and related risk factors: A systematic review and meta-analysis. Parasite, 2020; 27. https://doi.org/10.1051/parasite/2020025.