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Clinical Assessment of Using Local Anesthetic Articaine 4% with 1:100,000 Epinephrine for Inferior Alveolar Nerve Block Comparing It with Lidocaine 2% with 1:100,000 Epinephrine

Received: 11 July 2015    Accepted: 24 July 2015    Published: 28 July 2015
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Abstract

Objectives: This study was carried out to study the efficacy and the anesthetic characters of using Articaine 4 % with 1:100,000 Epinephrine as a local anesthetic drug in surgical practice through inferior alveolar nerve block and comparing it with Lidocaine 2% with 1:100,000 Epinephrine. Materials and methods: Thirty patients in two groups, fifteen patients each, undergo extraction of impacted mandibular third molar, Inferior Alveolar Nerve block had been carried out using either Articaine 4% or Lidocaine 2% Local anesthetic drugs. Results: Articaine was well-tolerated and it provided clinically effective pain relief during surgical procedures and it was as potent as Lidocaine and provided similar clinical effect to Lidocaine (Gold standard). Conclusions: On the basis of our findings, we recommend using Articaine 4% as local anesthetic drug in minor oral surgery

Published in International Journal of Clinical Oral and Maxillofacial Surgery (Volume 1, Issue 2)
DOI 10.11648/j.ijcoms.20150102.12
Page(s) 17-19
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Articaine, Lidocaine, Inferior Alveolar Nerve Block

References
[1] Hunter JP and Simmonds MJ. Pain: Putting the Whole Person at the Centre. Physiother Can.; 62: 1–4, 2010.
[2] Pozos AJ, Martínez R, Aguirre P, et al., Tramadol Administered in a Combination of Routes for Reducing Pain After Removal of an Impacted Mandibular Third Molar.J oral maxillofac sur.; Volume 65, Issue 8, Pages 1633–1639,2007
[3] Mojumdar E. H. and Lyubartsev A. P. Molecular dynamics simulations of local anesthetic articaine in a lipid bilaye. Biophysical Chemistry; vol. 153, no. 1, pp. 27–35, 2010.
[4] Malamed SF. Handbook of local anesthesia. 4th ed Mosby, St.Louis, 1997.
[5] Malamed SF. Clinical action of specific agents. In: Handbook of local anesthesia, 5th edn. Mosby, St Louis, pp 61–65 and 71–73. 2007.
[6] Dugal A, Khanna R and Patankar A. A comparative study between 0.5% Centbucridine HCl and 2% Lignocaine HCl with adrenaline (1:200000). J Maxillofac Oral Surg; 8:221–223, 2009.
[7] Moore PA, Boynes SG, Hersh EV et al., The anesthetic efficacy of 4% Articaine 1:200000 epinephrine. J Am Dent Assoc; 137:1572–1581, 2006.
[8] Colombini BL, Modena KC, Calvo AM, et al., Articaine and Mepivacaine efficacy in post operative analgesia for lower third molar removal: a double-blind, randomized, cross over study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod;102:169–174. 2006.
[9] Rebolledo AS, Molina ED, Aytes LB et al., Comparative study of the anesthetic efficacy of 4% Articaine versus 2% Lidocaine in inferior alveolar nerve block during surgical extraction of impacted lower third molars. Med Oral Patol Oral Cir Bucal; 12:E139–E144, 2007.
[10] Gregorio L, Giglio F, Sakai V, Modena KC et al ., A comparison of the clinical anesthetic efficacy of 4% Articaine and 0.5% Bupivaciane (both with 1:200000 epinephrine) for lower third molar removal. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 106:19–28, 2008.
[11] Shruthi R, Kedarnath N, Mamatha N, et al Articaine for surgical removal of impacted third molar; a comparison with lignocaine. J Int Oral Health; 5:48-53, 2013.
[12] Gordon SM, Dionne RA, Brahim J et al., Blockade of peripheral neuronal barrage reduces postoperative pain. Pain; 70: 209-215, 1997.
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    Mohamed Hossam Moselhy, Eman A. El-Sharrawy, Abdel Badia Abdallah Abdel Mabood. (2015). Clinical Assessment of Using Local Anesthetic Articaine 4% with 1:100,000 Epinephrine for Inferior Alveolar Nerve Block Comparing It with Lidocaine 2% with 1:100,000 Epinephrine. International Journal of Clinical Oral and Maxillofacial Surgery, 1(2), 17-19. https://doi.org/10.11648/j.ijcoms.20150102.12

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    ACS Style

    Mohamed Hossam Moselhy; Eman A. El-Sharrawy; Abdel Badia Abdallah Abdel Mabood. Clinical Assessment of Using Local Anesthetic Articaine 4% with 1:100,000 Epinephrine for Inferior Alveolar Nerve Block Comparing It with Lidocaine 2% with 1:100,000 Epinephrine. Int. J. Clin. Oral Maxillofac. Surg. 2015, 1(2), 17-19. doi: 10.11648/j.ijcoms.20150102.12

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    AMA Style

    Mohamed Hossam Moselhy, Eman A. El-Sharrawy, Abdel Badia Abdallah Abdel Mabood. Clinical Assessment of Using Local Anesthetic Articaine 4% with 1:100,000 Epinephrine for Inferior Alveolar Nerve Block Comparing It with Lidocaine 2% with 1:100,000 Epinephrine. Int J Clin Oral Maxillofac Surg. 2015;1(2):17-19. doi: 10.11648/j.ijcoms.20150102.12

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  • @article{10.11648/j.ijcoms.20150102.12,
      author = {Mohamed Hossam Moselhy and Eman A. El-Sharrawy and Abdel Badia Abdallah Abdel Mabood},
      title = {Clinical Assessment of Using Local Anesthetic Articaine 4% with 1:100,000 Epinephrine for Inferior Alveolar Nerve Block Comparing It with Lidocaine 2% with 1:100,000 Epinephrine},
      journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
      volume = {1},
      number = {2},
      pages = {17-19},
      doi = {10.11648/j.ijcoms.20150102.12},
      url = {https://doi.org/10.11648/j.ijcoms.20150102.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20150102.12},
      abstract = {Objectives: This study was carried out to study the efficacy and the anesthetic characters of using Articaine 4 % with 1:100,000 Epinephrine as a local anesthetic drug in surgical practice through inferior alveolar nerve block and comparing it with Lidocaine 2% with 1:100,000 Epinephrine. Materials and methods: Thirty patients in two groups, fifteen patients each, undergo extraction of impacted mandibular third molar, Inferior Alveolar Nerve block had been carried out using either Articaine 4% or Lidocaine 2% Local anesthetic drugs. Results: Articaine was well-tolerated and it provided clinically effective pain relief during surgical procedures and it was as potent as Lidocaine and provided similar clinical effect to Lidocaine (Gold standard). Conclusions: On the basis of our findings, we recommend using Articaine 4% as local anesthetic drug in minor oral surgery},
     year = {2015}
    }
    

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    T1  - Clinical Assessment of Using Local Anesthetic Articaine 4% with 1:100,000 Epinephrine for Inferior Alveolar Nerve Block Comparing It with Lidocaine 2% with 1:100,000 Epinephrine
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    JF  - International Journal of Clinical Oral and Maxillofacial Surgery
    JO  - International Journal of Clinical Oral and Maxillofacial Surgery
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    PB  - Science Publishing Group
    SN  - 2472-1344
    UR  - https://doi.org/10.11648/j.ijcoms.20150102.12
    AB  - Objectives: This study was carried out to study the efficacy and the anesthetic characters of using Articaine 4 % with 1:100,000 Epinephrine as a local anesthetic drug in surgical practice through inferior alveolar nerve block and comparing it with Lidocaine 2% with 1:100,000 Epinephrine. Materials and methods: Thirty patients in two groups, fifteen patients each, undergo extraction of impacted mandibular third molar, Inferior Alveolar Nerve block had been carried out using either Articaine 4% or Lidocaine 2% Local anesthetic drugs. Results: Articaine was well-tolerated and it provided clinically effective pain relief during surgical procedures and it was as potent as Lidocaine and provided similar clinical effect to Lidocaine (Gold standard). Conclusions: On the basis of our findings, we recommend using Articaine 4% as local anesthetic drug in minor oral surgery
    VL  - 1
    IS  - 2
    ER  - 

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Author Information
  • Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt

  • Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt

  • Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt

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