The central giant cell granuloma (CGCG) of the jaws is a rare benign tumour of the mandible (lower jaw) and the maxilla (upper jaw) characterized by destruction of the bone, loss of symmetry of the face and displacement of teeth and tooth germs, especially in younger patients. It is asymptomatic and present with slow growth often accompanied by dental mobility. The removal of this tumour is mutilating and is followed prosthetic rehabilitation. The aim of this study was to report a case of central giant cell granuloma localizated to the symphyseal region in a young patient. The case reported is that of a 14-year-old girl who received a consultation for a tumor in the symphysical region causing an aesthetic impact. The tumor was firm, painless and had been developing for about a year. The cortical were broken in places, in transverse, sagittal and coronal sections. The treatment consisted of her excision under general anesthesia causing a significant loss of substance. The tumor mass, very hemorrhagic, was extended to the buccal floor. At the end of the intervention, a significant loss of substance was observed. Two months later, a partial adjunct prosthesis was performed. The anatomo-pathological examination showed of several multinucleated giant cells, a few histiocytes, lymphocytes and fibroblasts. The removal of this aggressive tumour remains mutilating, with significant psychological repercussions. More recently, antiangiogenic therapy with interferon alpha has been successfully applied.
| Published in | International Journal of Clinical Oral and Maxillofacial Surgery (Volume 6, Issue 2) |
| DOI | 10.11648/j.ijcoms.20200602.14 |
| Page(s) | 40-43 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Central Giant Cell Granuloma, Mandible, Removal
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APA Style
Babacar Tamba, Mouhammad Kane, Mamadou Diatta, Bintou Catherine Gassama, Alpha Kounta, et al. (2020). Central Giant Cell Granuloma of the Mandible: A Case Report. International Journal of Clinical Oral and Maxillofacial Surgery, 6(2), 40-43. https://doi.org/10.11648/j.ijcoms.20200602.14
ACS Style
Babacar Tamba; Mouhammad Kane; Mamadou Diatta; Bintou Catherine Gassama; Alpha Kounta, et al. Central Giant Cell Granuloma of the Mandible: A Case Report. Int. J. Clin. Oral Maxillofac. Surg. 2020, 6(2), 40-43. doi: 10.11648/j.ijcoms.20200602.14
AMA Style
Babacar Tamba, Mouhammad Kane, Mamadou Diatta, Bintou Catherine Gassama, Alpha Kounta, et al. Central Giant Cell Granuloma of the Mandible: A Case Report. Int J Clin Oral Maxillofac Surg. 2020;6(2):40-43. doi: 10.11648/j.ijcoms.20200602.14
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Download@article{10.11648/j.ijcoms.20200602.14,
author = {Babacar Tamba and Mouhammad Kane and Mamadou Diatta and Bintou Catherine Gassama and Alpha Kounta and Abdou Ba and Ndeye Fatou Kebe and Soukeye Dia Tine},
title = {Central Giant Cell Granuloma of the Mandible: A Case Report},
journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
volume = {6},
number = {2},
pages = {40-43},
doi = {10.11648/j.ijcoms.20200602.14},
url = {https://doi.org/10.11648/j.ijcoms.20200602.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20200602.14},
abstract = {The central giant cell granuloma (CGCG) of the jaws is a rare benign tumour of the mandible (lower jaw) and the maxilla (upper jaw) characterized by destruction of the bone, loss of symmetry of the face and displacement of teeth and tooth germs, especially in younger patients. It is asymptomatic and present with slow growth often accompanied by dental mobility. The removal of this tumour is mutilating and is followed prosthetic rehabilitation. The aim of this study was to report a case of central giant cell granuloma localizated to the symphyseal region in a young patient. The case reported is that of a 14-year-old girl who received a consultation for a tumor in the symphysical region causing an aesthetic impact. The tumor was firm, painless and had been developing for about a year. The cortical were broken in places, in transverse, sagittal and coronal sections. The treatment consisted of her excision under general anesthesia causing a significant loss of substance. The tumor mass, very hemorrhagic, was extended to the buccal floor. At the end of the intervention, a significant loss of substance was observed. Two months later, a partial adjunct prosthesis was performed. The anatomo-pathological examination showed of several multinucleated giant cells, a few histiocytes, lymphocytes and fibroblasts. The removal of this aggressive tumour remains mutilating, with significant psychological repercussions. More recently, antiangiogenic therapy with interferon alpha has been successfully applied.},
year = {2020}
}
TY - JOUR T1 - Central Giant Cell Granuloma of the Mandible: A Case Report AU - Babacar Tamba AU - Mouhammad Kane AU - Mamadou Diatta AU - Bintou Catherine Gassama AU - Alpha Kounta AU - Abdou Ba AU - Ndeye Fatou Kebe AU - Soukeye Dia Tine Y1 - 2020/08/13 PY - 2020 N1 - https://doi.org/10.11648/j.ijcoms.20200602.14 DO - 10.11648/j.ijcoms.20200602.14 T2 - International Journal of Clinical Oral and Maxillofacial Surgery JF - International Journal of Clinical Oral and Maxillofacial Surgery JO - International Journal of Clinical Oral and Maxillofacial Surgery SP - 40 EP - 43 PB - Science Publishing Group SN - 2472-1344 UR - https://doi.org/10.11648/j.ijcoms.20200602.14 AB - The central giant cell granuloma (CGCG) of the jaws is a rare benign tumour of the mandible (lower jaw) and the maxilla (upper jaw) characterized by destruction of the bone, loss of symmetry of the face and displacement of teeth and tooth germs, especially in younger patients. It is asymptomatic and present with slow growth often accompanied by dental mobility. The removal of this tumour is mutilating and is followed prosthetic rehabilitation. The aim of this study was to report a case of central giant cell granuloma localizated to the symphyseal region in a young patient. The case reported is that of a 14-year-old girl who received a consultation for a tumor in the symphysical region causing an aesthetic impact. The tumor was firm, painless and had been developing for about a year. The cortical were broken in places, in transverse, sagittal and coronal sections. The treatment consisted of her excision under general anesthesia causing a significant loss of substance. The tumor mass, very hemorrhagic, was extended to the buccal floor. At the end of the intervention, a significant loss of substance was observed. Two months later, a partial adjunct prosthesis was performed. The anatomo-pathological examination showed of several multinucleated giant cells, a few histiocytes, lymphocytes and fibroblasts. The removal of this aggressive tumour remains mutilating, with significant psychological repercussions. More recently, antiangiogenic therapy with interferon alpha has been successfully applied. VL - 6 IS - 2 ER -
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