International Journal of Otorhinolaryngology

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Prophylactic Tobramycin Drops After Tympanostomy Tube Placement

Received: 08 January 2018    Accepted: 20 January 2018    Published: 21 February 2018
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Abstract

Tympanostomy tube insertion remains one of the most commonly performed surgeries in ENT practice. Post-operative infections remain one of the common complications after surgeries. Topical antibiotic ear drops are used to reduce the risk of this complication. The aim of this study was to assess the role of antibiotic ear drops (Tobramycin) in prevention of post-operative infection. A randomized controlled trial was done on 84 patients complaining of bilateral secretory otitis media, were operated using ventilation tube insertion. All patients were randomly allocated into two groups. The first group (group A) was the intervention group, in which all patients were given local tobramycin ear drops for five days post operatively to decrease otorrhea. The other group (group B) was the control group and no ear drops were prescribed post operatively. All patients in both groups were followed up to 14 days post operatively. A statistically significant decrease was observed in the incidence of post tympanostomy otorrhea and infections between the treatment group (group A = 7.1%), and the control group (group B = 14.2 %) (P<0.05). To conclude, antibiotic ear drops should be prescribed to all patients who are undergoing tympanostomy tube insertion. A 5-day course post operatively with tobramycin local drops is recommended.

DOI 10.11648/j.ijo.20180401.12
Published in International Journal of Otorhinolaryngology (Volume 4, Issue 1, June 2018)
Page(s) 6-10
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Tympanostomy Tube, Secondary Infection, Antibiotic Ear Drop

References
[1] Kogan MD, Overpeck MD, Hoffman HJ, et al. Factors associated with tympanostomy tube insertion among preschool-aged children in the United States. Am. J. Public Health. 2000; 90:245–250.
[2] Steele DW, Adam GP, Di M, et al. Effectiveness of Tympanostomy Tubes for Otitis Media: A Meta-analysis. Pediatrics. 2017; 139.
[3] Centers for Disease Control and Prevention. Table 2: top 5 diagnoses at visits to office-based physicians and hospital outpatient departments by patient age and sex: United States 2008. Atlanta, GA: Centers for Disease Control and Prevention; 2008.
[4] Bluestone CD, Swarts JD. Human evolutionary history: consequences for the pathogenesis of otitis media. Otolaryngol.--Head Neck Surg. Off. J. Am. Acad. Otolaryngol.-Head Neck Surg. 2010; 143:739–744.
[5] Rosenfeld RM, Culpepper L, Doyle KJ, et al. Clinical practice guideline: Otitis media with effusion. Otolaryngol.--Head Neck Surg. Off. J. Am. Acad. Otolaryngol.-Head Neck Surg. 2004; 130:S95-118.
[6] Rosenfeld RM, Shin JJ, Schwartz SR, et al. Clinical Practice Guideline: Otitis Media with Effusion (Update). Otolaryngol.--Head Neck Surg. Off. J. Am. Acad. Otolaryngol.-Head Neck Surg. 2016; 154:S1–S41.
[7] Browning GG, Rovers MM, Williamson I, et al. Grommets (ventilation tubes) for hearing loss associated with otitis media with effusion in children. Cochrane Database Syst. Rev. [Internet]. John Wiley & Sons, Ltd; 2010.
[8] Lous J, Ryborg CT, Thomsen JL. A systematic review of the effect of tympanostomy tubes in children with recurrent acute otitis media. Int. J. Pediatr. Otorhinolaryngol. 2011; 75:1058–1061.
[9] Rosenfeld RM, Bhaya MH, Bower CM, et al. Impact of tympanostomy tubes on child quality of life. Arch. Otolaryngol. Head Neck Surg. 2000; 126:585–592.
[10] Kay DJ, Nelson M, Rosenfeld RM. Meta-Analysis of Tympanostomy Tube Sequelae. Otolaryngol.-Head Neck Surg. 2001; 124:374–380.
[11] Badalyan V, Schwartz RH, Scwhartz SL, et al. Draining ears and tympanostomy tubes: a survey of pediatric otolaryngologists and pediatric emergency medicine physicians. Pediatr. Emerg. Care. 2013; 29:203–208.
[12] Elden LM, Marsh RR. Survey of pediatric otolaryngologists: clinical practice trends used to prevent and treat blocked ventilation ear tubes in children. Int. J. Pediatr. Otorhinolaryngol. 2006; 70:1533–1538.
[13] Altman JS, Haupert MS, Hamaker RA, et al. Phenylephrine and the prevention of postoperative tympanostomy tube obstruction. Arch. Otolaryngol. Head Neck Surg. 1998; 124:1233–1236.
[14] Shishehgar M, Rahmanian AM. Phenylephrine and the prevention of post operative tympanostomy tube obstruction. 2004; 16:40–47.
[15] Hester TO, Jones RO, Archer SM, et al. Prophylactic antibiotic drops after tympanostomy tube placement. Arch. Otolaryngol. Head Neck Surg. 1995; 121:445–448.
[16] Ramadan HH, Tarazi T, Zaytoun GM. Use of prophylactic otic drops after tympanostomy tube insertion. Arch. Otolaryngol. Head Neck Surg. 1991; 117:537.
Author Information
  • Department of Otorhinolaryngology, Misrata Central Hospital, Misrata, Libya

  • Department of Otorhinolaryngology, Iben Sina Hospital, Sirt, Libya

  • Department of Otorhinolaryngology, Misrata Central Hospital, Misrata, Libya

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    Abdussalam Mohamed Jahan, Basheer Ali Al hanash, Abdulhakim Yousef Ben Ghuzi. (2018). Prophylactic Tobramycin Drops After Tympanostomy Tube Placement. International Journal of Otorhinolaryngology, 4(1), 6-10. https://doi.org/10.11648/j.ijo.20180401.12

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    ACS Style

    Abdussalam Mohamed Jahan; Basheer Ali Al hanash; Abdulhakim Yousef Ben Ghuzi. Prophylactic Tobramycin Drops After Tympanostomy Tube Placement. Int. J. Otorhinolaryngol. 2018, 4(1), 6-10. doi: 10.11648/j.ijo.20180401.12

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    AMA Style

    Abdussalam Mohamed Jahan, Basheer Ali Al hanash, Abdulhakim Yousef Ben Ghuzi. Prophylactic Tobramycin Drops After Tympanostomy Tube Placement. Int J Otorhinolaryngol. 2018;4(1):6-10. doi: 10.11648/j.ijo.20180401.12

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  • @article{10.11648/j.ijo.20180401.12,
      author = {Abdussalam Mohamed Jahan and Basheer Ali Al hanash and Abdulhakim Yousef Ben Ghuzi},
      title = {Prophylactic Tobramycin Drops After Tympanostomy Tube Placement},
      journal = {International Journal of Otorhinolaryngology},
      volume = {4},
      number = {1},
      pages = {6-10},
      doi = {10.11648/j.ijo.20180401.12},
      url = {https://doi.org/10.11648/j.ijo.20180401.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijo.20180401.12},
      abstract = {Tympanostomy tube insertion remains one of the most commonly performed surgeries in ENT practice. Post-operative infections remain one of the common complications after surgeries. Topical antibiotic ear drops are used to reduce the risk of this complication. The aim of this study was to assess the role of antibiotic ear drops (Tobramycin) in prevention of post-operative infection. A randomized controlled trial was done on 84 patients complaining of bilateral secretory otitis media, were operated using ventilation tube insertion. All patients were randomly allocated into two groups. The first group (group A) was the intervention group, in which all patients were given local tobramycin ear drops for five days post operatively to decrease otorrhea. The other group (group B) was the control group and no ear drops were prescribed post operatively. All patients in both groups were followed up to 14 days post operatively. A statistically significant decrease was observed in the incidence of post tympanostomy otorrhea and infections between the treatment group (group A = 7.1%), and the control group (group B = 14.2 %) (P<0.05). To conclude, antibiotic ear drops should be prescribed to all patients who are undergoing tympanostomy tube insertion. A 5-day course post operatively with tobramycin local drops is recommended.},
     year = {2018}
    }
    

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  • TY  - JOUR
    T1  - Prophylactic Tobramycin Drops After Tympanostomy Tube Placement
    AU  - Abdussalam Mohamed Jahan
    AU  - Basheer Ali Al hanash
    AU  - Abdulhakim Yousef Ben Ghuzi
    Y1  - 2018/02/21
    PY  - 2018
    N1  - https://doi.org/10.11648/j.ijo.20180401.12
    DO  - 10.11648/j.ijo.20180401.12
    T2  - International Journal of Otorhinolaryngology
    JF  - International Journal of Otorhinolaryngology
    JO  - International Journal of Otorhinolaryngology
    SP  - 6
    EP  - 10
    PB  - Science Publishing Group
    SN  - 2472-2413
    UR  - https://doi.org/10.11648/j.ijo.20180401.12
    AB  - Tympanostomy tube insertion remains one of the most commonly performed surgeries in ENT practice. Post-operative infections remain one of the common complications after surgeries. Topical antibiotic ear drops are used to reduce the risk of this complication. The aim of this study was to assess the role of antibiotic ear drops (Tobramycin) in prevention of post-operative infection. A randomized controlled trial was done on 84 patients complaining of bilateral secretory otitis media, were operated using ventilation tube insertion. All patients were randomly allocated into two groups. The first group (group A) was the intervention group, in which all patients were given local tobramycin ear drops for five days post operatively to decrease otorrhea. The other group (group B) was the control group and no ear drops were prescribed post operatively. All patients in both groups were followed up to 14 days post operatively. A statistically significant decrease was observed in the incidence of post tympanostomy otorrhea and infections between the treatment group (group A = 7.1%), and the control group (group B = 14.2 %) (P<0.05). To conclude, antibiotic ear drops should be prescribed to all patients who are undergoing tympanostomy tube insertion. A 5-day course post operatively with tobramycin local drops is recommended.
    VL  - 4
    IS  - 1
    ER  - 

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