American Journal of Biological and Environmental Statistics

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Lead Exposure and Liver Function Parameters in Iraqi Workers

Received: 14 June 2019    Accepted: 28 August 2019    Published: 16 September 2019
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Abstract

This study was conducted to evaluate the incidence of long term exposure to lead in some biomarkers of liver functions of Iraqi workers. A total ninety –two (92) adult Iraqi workers with a mean ages (37 ± 1.107 years) were distributed as follows; twenty eight (28) gasoline filling station workers, thirty one (31) battery workers and thirty three (33) brick manufacturing industry workers as well as, eighteen (18) control subjects were not in any way occupationally exposed to lead were involved in this study. The lead level was measured using atomic absorption spectrophotometer method. The blood lead level (BLL) among gasoline station, battery and brick kiln workers were (24.96 ± 0.76, 24.7 ± 0.77 and 24.63 ± 0.81μg/dL, respectively), and the corresponding values for the control group was significantly (p < 0.001) lower (18.88 ± 0.51μg/dL). Significant (p<0.05) elevation in serum alanine transaminase (ALT) activity in gasoline filling station workers, battery manufacture and brick kiln workers among the control group was recorded, while no significant change in serum aspartate transaminase (AST) of all workers versus control was observed. Moreover, significant (p<0.01) increase in alkaline phosphatase activity in the serum of all workers as compared to the control group was recorded. On the other hand, no significant change was listed in albumin and bilirubin in all lead exposed groups. It can be concluded that occupational exposure to lead in Iraq is associated with significant increase of lead level, increased prevalence of lead toxicity and liver dysfunction.

DOI 10.11648/j.ajbes.20190503.12
Published in American Journal of Biological and Environmental Statistics (Volume 5, Issue 3, September 2019)
Page(s) 42-45
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Component, Occupational Exposure, Blood Lead Level, Biochemical Parameters, Gasoline Station, Battery, Brick Kiln Workers

References
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Author Information
  • Medical Laboratory Technique, Dijlah University College, Baghdad, Iraq

  • Medical Laboratory Technique, Dijlah University College, Baghdad, Iraq

  • Medical Laboratory Technique, Dijlah University College, Baghdad, Iraq

  • Medical Laboratory Technique, Dijlah University College, Baghdad, Iraq

  • Medical Laboratory Technique, Dijlah University College, Baghdad, Iraq

  • Medical Laboratory Technique, Dijlah University College, Baghdad, Iraq

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  • APA Style

    Kahtan Ahmed Al-Mzaien, Meena Mohammed Abdul-Hussein, Jafar Ihsan Hussein, Ahmed Abdul-Qadir, Sufian Abdul-Rahman, et al. (2019). Lead Exposure and Liver Function Parameters in Iraqi Workers. American Journal of Biological and Environmental Statistics, 5(3), 42-45. https://doi.org/10.11648/j.ajbes.20190503.12

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    ACS Style

    Kahtan Ahmed Al-Mzaien; Meena Mohammed Abdul-Hussein; Jafar Ihsan Hussein; Ahmed Abdul-Qadir; Sufian Abdul-Rahman, et al. Lead Exposure and Liver Function Parameters in Iraqi Workers. Am. J. Biol. Environ. Stat. 2019, 5(3), 42-45. doi: 10.11648/j.ajbes.20190503.12

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    AMA Style

    Kahtan Ahmed Al-Mzaien, Meena Mohammed Abdul-Hussein, Jafar Ihsan Hussein, Ahmed Abdul-Qadir, Sufian Abdul-Rahman, et al. Lead Exposure and Liver Function Parameters in Iraqi Workers. Am J Biol Environ Stat. 2019;5(3):42-45. doi: 10.11648/j.ajbes.20190503.12

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  • @article{10.11648/j.ajbes.20190503.12,
      author = {Kahtan Ahmed Al-Mzaien and Meena Mohammed Abdul-Hussein and Jafar Ihsan Hussein and Ahmed Abdul-Qadir and Sufian Abdul-Rahman and Hussam-Aldeen Sami},
      title = {Lead Exposure and Liver Function Parameters in Iraqi Workers},
      journal = {American Journal of Biological and Environmental Statistics},
      volume = {5},
      number = {3},
      pages = {42-45},
      doi = {10.11648/j.ajbes.20190503.12},
      url = {https://doi.org/10.11648/j.ajbes.20190503.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajbes.20190503.12},
      abstract = {This study was conducted to evaluate the incidence of long term exposure to lead in some biomarkers of liver functions of Iraqi workers. A total ninety –two (92) adult Iraqi workers with a mean ages (37 ± 1.107 years) were distributed as follows; twenty eight (28) gasoline filling station workers, thirty one (31) battery workers and thirty three (33) brick manufacturing industry workers as well as, eighteen (18) control subjects were not in any way occupationally exposed to lead were involved in this study. The lead level was measured using atomic absorption spectrophotometer method. The blood lead level (BLL) among gasoline station, battery and brick kiln workers were (24.96 ± 0.76, 24.7 ± 0.77 and 24.63 ± 0.81μg/dL, respectively), and the corresponding values for the control group was significantly (p μg/dL). Significant (p<0.05) elevation in serum alanine transaminase (ALT) activity in gasoline filling station workers, battery manufacture and brick kiln workers among the control group was recorded, while no significant change in serum aspartate transaminase (AST) of all workers versus control was observed. Moreover, significant (p<0.01) increase in alkaline phosphatase activity in the serum of all workers as compared to the control group was recorded. On the other hand, no significant change was listed in albumin and bilirubin in all lead exposed groups. It can be concluded that occupational exposure to lead in Iraq is associated with significant increase of lead level, increased prevalence of lead toxicity and liver dysfunction.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Lead Exposure and Liver Function Parameters in Iraqi Workers
    AU  - Kahtan Ahmed Al-Mzaien
    AU  - Meena Mohammed Abdul-Hussein
    AU  - Jafar Ihsan Hussein
    AU  - Ahmed Abdul-Qadir
    AU  - Sufian Abdul-Rahman
    AU  - Hussam-Aldeen Sami
    Y1  - 2019/09/16
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ajbes.20190503.12
    DO  - 10.11648/j.ajbes.20190503.12
    T2  - American Journal of Biological and Environmental Statistics
    JF  - American Journal of Biological and Environmental Statistics
    JO  - American Journal of Biological and Environmental Statistics
    SP  - 42
    EP  - 45
    PB  - Science Publishing Group
    SN  - 2471-979X
    UR  - https://doi.org/10.11648/j.ajbes.20190503.12
    AB  - This study was conducted to evaluate the incidence of long term exposure to lead in some biomarkers of liver functions of Iraqi workers. A total ninety –two (92) adult Iraqi workers with a mean ages (37 ± 1.107 years) were distributed as follows; twenty eight (28) gasoline filling station workers, thirty one (31) battery workers and thirty three (33) brick manufacturing industry workers as well as, eighteen (18) control subjects were not in any way occupationally exposed to lead were involved in this study. The lead level was measured using atomic absorption spectrophotometer method. The blood lead level (BLL) among gasoline station, battery and brick kiln workers were (24.96 ± 0.76, 24.7 ± 0.77 and 24.63 ± 0.81μg/dL, respectively), and the corresponding values for the control group was significantly (p μg/dL). Significant (p<0.05) elevation in serum alanine transaminase (ALT) activity in gasoline filling station workers, battery manufacture and brick kiln workers among the control group was recorded, while no significant change in serum aspartate transaminase (AST) of all workers versus control was observed. Moreover, significant (p<0.01) increase in alkaline phosphatase activity in the serum of all workers as compared to the control group was recorded. On the other hand, no significant change was listed in albumin and bilirubin in all lead exposed groups. It can be concluded that occupational exposure to lead in Iraq is associated with significant increase of lead level, increased prevalence of lead toxicity and liver dysfunction.
    VL  - 5
    IS  - 3
    ER  - 

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