Toxoplasma gondii and Plasmodium species are both endemic apicomplexan parasites that have been incriminated in the cause of febrile illnesses in children in the sub-Saharan regions of Africa. Moreover these parasites have some common routes of transmission, common receptors for pathogenicity and both effect or of some hematological parameters. Despites this, little is known about the prevalence of toxoplasmosis and malaria co-infection in Cameroon and their effects on hematological parameters and malaria parasite density. Venous blood was collected from 315 febrile children in the Nkolbisson Health District found in Yaoundé Cameroon. For each participant: RDT for Toxoplasma gondii, Toxoplasma gondii IgG avidity test, thick film microscopy and full blood count was performed. The prevalence of toxoplasmosis was 40%, malaria 42.8% and toxoplasmosis and malaria co-infection 20%. The age group 0-5 years was identified as risk group for both infections and Nkol-Atem had the highest prevalence of both infections. Toxoplasmosis and malaria of co-infection led to a slight increase in RBCs, WBCs, and platelets counts in our study population. This could therefore be suggestive of a mechanism between the two parasites that may improve the physiology of blood cells production. However the presence of a co-infection did not show any influence on the malaria parasite density. This study provides valuable information on the prevalence of malaria and toxoplasmosis co-infection in Cameroonian children where data is almost unavailable. This study thus indicates a need to enforce control and preventive measures against these infections in Cameroonian children.
| Published in | Journal of Family Medicine and Health Care (Volume 2, Issue 4) |
| DOI | 10.11648/j.jfmhc.20160204.19 |
| Page(s) | 81-88 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Toxoplasmosis, Malaria, Coinfection, Children, Cameroon
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APA Style
Samuel Nambile Cumber, Kameni Nguekam Yvonne-Estelle, Shalom Jaila. (2016). The Effects of Toxoplasmosis and Malaria Coinfection on Malaria Parasite Density and Hematological Parameters in Children (0-6 Years) in the Nkolbisson Health District, Cameroon. Journal of Family Medicine and Health Care, 2(4), 81-88. https://doi.org/10.11648/j.jfmhc.20160204.19
ACS Style
Samuel Nambile Cumber; Kameni Nguekam Yvonne-Estelle; Shalom Jaila. The Effects of Toxoplasmosis and Malaria Coinfection on Malaria Parasite Density and Hematological Parameters in Children (0-6 Years) in the Nkolbisson Health District, Cameroon. J. Fam. Med. Health Care 2016, 2(4), 81-88. doi: 10.11648/j.jfmhc.20160204.19
AMA Style
Samuel Nambile Cumber, Kameni Nguekam Yvonne-Estelle, Shalom Jaila. The Effects of Toxoplasmosis and Malaria Coinfection on Malaria Parasite Density and Hematological Parameters in Children (0-6 Years) in the Nkolbisson Health District, Cameroon. J Fam Med Health Care. 2016;2(4):81-88. doi: 10.11648/j.jfmhc.20160204.19
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Download@article{10.11648/j.jfmhc.20160204.19,
author = {Samuel Nambile Cumber and Kameni Nguekam Yvonne-Estelle and Shalom Jaila},
title = {The Effects of Toxoplasmosis and Malaria Coinfection on Malaria Parasite Density and Hematological Parameters in Children (0-6 Years) in the Nkolbisson Health District, Cameroon},
journal = {Journal of Family Medicine and Health Care},
volume = {2},
number = {4},
pages = {81-88},
doi = {10.11648/j.jfmhc.20160204.19},
url = {https://doi.org/10.11648/j.jfmhc.20160204.19},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jfmhc.20160204.19},
abstract = {Toxoplasma gondii and Plasmodium species are both endemic apicomplexan parasites that have been incriminated in the cause of febrile illnesses in children in the sub-Saharan regions of Africa. Moreover these parasites have some common routes of transmission, common receptors for pathogenicity and both effect or of some hematological parameters. Despites this, little is known about the prevalence of toxoplasmosis and malaria co-infection in Cameroon and their effects on hematological parameters and malaria parasite density. Venous blood was collected from 315 febrile children in the Nkolbisson Health District found in Yaoundé Cameroon. For each participant: RDT for Toxoplasma gondii, Toxoplasma gondii IgG avidity test, thick film microscopy and full blood count was performed. The prevalence of toxoplasmosis was 40%, malaria 42.8% and toxoplasmosis and malaria co-infection 20%. The age group 0-5 years was identified as risk group for both infections and Nkol-Atem had the highest prevalence of both infections. Toxoplasmosis and malaria of co-infection led to a slight increase in RBCs, WBCs, and platelets counts in our study population. This could therefore be suggestive of a mechanism between the two parasites that may improve the physiology of blood cells production. However the presence of a co-infection did not show any influence on the malaria parasite density. This study provides valuable information on the prevalence of malaria and toxoplasmosis co-infection in Cameroonian children where data is almost unavailable. This study thus indicates a need to enforce control and preventive measures against these infections in Cameroonian children.},
year = {2016}
}
TY - JOUR T1 - The Effects of Toxoplasmosis and Malaria Coinfection on Malaria Parasite Density and Hematological Parameters in Children (0-6 Years) in the Nkolbisson Health District, Cameroon AU - Samuel Nambile Cumber AU - Kameni Nguekam Yvonne-Estelle AU - Shalom Jaila Y1 - 2016/11/23 PY - 2016 N1 - https://doi.org/10.11648/j.jfmhc.20160204.19 DO - 10.11648/j.jfmhc.20160204.19 T2 - Journal of Family Medicine and Health Care JF - Journal of Family Medicine and Health Care JO - Journal of Family Medicine and Health Care SP - 81 EP - 88 PB - Science Publishing Group SN - 2469-8342 UR - https://doi.org/10.11648/j.jfmhc.20160204.19 AB - Toxoplasma gondii and Plasmodium species are both endemic apicomplexan parasites that have been incriminated in the cause of febrile illnesses in children in the sub-Saharan regions of Africa. Moreover these parasites have some common routes of transmission, common receptors for pathogenicity and both effect or of some hematological parameters. Despites this, little is known about the prevalence of toxoplasmosis and malaria co-infection in Cameroon and their effects on hematological parameters and malaria parasite density. Venous blood was collected from 315 febrile children in the Nkolbisson Health District found in Yaoundé Cameroon. For each participant: RDT for Toxoplasma gondii, Toxoplasma gondii IgG avidity test, thick film microscopy and full blood count was performed. The prevalence of toxoplasmosis was 40%, malaria 42.8% and toxoplasmosis and malaria co-infection 20%. The age group 0-5 years was identified as risk group for both infections and Nkol-Atem had the highest prevalence of both infections. Toxoplasmosis and malaria of co-infection led to a slight increase in RBCs, WBCs, and platelets counts in our study population. This could therefore be suggestive of a mechanism between the two parasites that may improve the physiology of blood cells production. However the presence of a co-infection did not show any influence on the malaria parasite density. This study provides valuable information on the prevalence of malaria and toxoplasmosis co-infection in Cameroonian children where data is almost unavailable. This study thus indicates a need to enforce control and preventive measures against these infections in Cameroonian children. VL - 2 IS - 4 ER -
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