CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of <i>Acacia Nilotica</i>

Md. Mamun-Or-Rashid; Muhammad Ashiqul Islam; Taniya Idris; Md. Shah Amran

doi:doi:10.11648/j.pst.20170102.11

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CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica

Md. Mamun-Or-Rashid, Muhammad Ashiqul Islam, Taniya Idris, Md. Shah Amran

Published in Pharmaceutical Science and Technology (Volume 1, Issue 2)

Received: 16 June 2017 Accepted: 5 July 2017 Published: 16 August 2017

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Abstract

According to the World Health Report, approximately 450 million people suffer from a mental or behavioral disorder. This amounts of 12.3% of the global burden of disease, and will rise to 15% by 2020. Depression is most prevalent mental disorder and it is recognized to be symptomatically, psychologically and biologically heterogeneous. The crude methanolic extract of Acacia nilotica bark with different soluble partitionates were subjected to investigate for the evaluation of analgesic, hypoglycemic, CNS depressant and antidiarrheal activity on mice and thrombolytic, antihelmentic, antimicrobial, antioxidant along with cytotoxicity different in vivo experiment. The crude methanolic extract of bark of Acacia nilotica were evaluated for antidepressant activity showed insignificant value.

Published in	Pharmaceutical Science and Technology (Volume 1, Issue 2)
DOI	10.11648/j.pst.20170102.11
Page(s)	13-19
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Acacia Nilotica, CNS-Antidepressant Activity, Stem Bark and Methanolic Extract

References

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[7]	McKey, D. 1994. Legumes and nitrogen: the evolutionary ecology of a nitrogen-demanding lifestyle. Pages 211–228 in Advances in Legume Systematics, part 5, the nitrogen factor (J. I. Sprent and D. McKey, eds.). Royal Botanic Gardens, Kew, UK.
[8]	Polhill, R. M. 1994. Classification of the Leguminosae. Pages xxxv–xlviii in Phytochemical Dictionary of the Leguminosae (F. A. Bisby, J. Buckingham, and J. B. Harborne, eds.). Chapman and Hall, New York, NY.
[9]	Polhill, R. M., and P. H. Raven (eds.). 1981. Advances in legume systematics, parts 1 and 2. Royal Botanic Gardens, Kew, UK.
[10]	Graham, P. H., and C. P. Vance. 2003. Legumes: importance and constraints to greater use. Plant Physiol. 131: 872 – 877.
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[13]	Bargal Kiran, Bargali S. S. (2009). Acacia nilotica: a multipurpose leguminous plant. Nature and Science, 7(4): 11-19. 9.
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[17]	Baravkar AA, Kale RN, Patil RN, Sawant SD (2008). Pharmaceutical and biological evaluation of formulated cream of methanolic extract of Acacia nilotica leaves. Res. J. Pharm. Technol., 1(4): 481-483.
[18]	Agrawal S, Kulkarni GT, Sharma VN (2010). A comparative study on the antioxidant activity of methanol extracts of acacia. Adv. Nat. Appl. Sci., 4(1): 78-84.
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APA Style

Md. Mamun-Or-Rashid, Muhammad Ashiqul Islam, Taniya Idris, Md. Shah Amran. (2017). CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica. Pharmaceutical Science and Technology, 1(2), 13-19. https://doi.org/10.11648/j.pst.20170102.11

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ACS Style

Md. Mamun-Or-Rashid; Muhammad Ashiqul Islam; Taniya Idris; Md. Shah Amran. CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica. Pharm. Sci. Technol. 2017, 1(2), 13-19. doi: 10.11648/j.pst.20170102.11

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AMA Style

Md. Mamun-Or-Rashid, Muhammad Ashiqul Islam, Taniya Idris, Md. Shah Amran. CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica. Pharm Sci Technol. 2017;1(2):13-19. doi: 10.11648/j.pst.20170102.11

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@article{10.11648/j.pst.20170102.11,
  author = {Md. Mamun-Or-Rashid and Muhammad Ashiqul Islam and Taniya Idris and Md. Shah Amran},
  title = {CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica},
  journal = {Pharmaceutical Science and Technology},
  volume = {1},
  number = {2},
  pages = {13-19},
  doi = {10.11648/j.pst.20170102.11},
  url = {https://doi.org/10.11648/j.pst.20170102.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.pst.20170102.11},
  abstract = {According to the World Health Report, approximately 450 million people suffer from a mental or behavioral disorder. This amounts of 12.3% of the global burden of disease, and will rise to 15% by 2020. Depression is most prevalent mental disorder and it is recognized to be symptomatically, psychologically and biologically heterogeneous. The crude methanolic extract of Acacia nilotica bark with different soluble partitionates were subjected to investigate for the evaluation of analgesic, hypoglycemic, CNS depressant and antidiarrheal activity on mice and thrombolytic, antihelmentic, antimicrobial, antioxidant along with cytotoxicity different in vivo experiment. The crude methanolic extract of bark of Acacia nilotica were evaluated for antidepressant activity showed insignificant value.},
 year = {2017}
}

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TY  - JOUR
T1  - CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica
AU  - Md. Mamun-Or-Rashid
AU  - Muhammad Ashiqul Islam
AU  - Taniya Idris
AU  - Md. Shah Amran
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DO  - 10.11648/j.pst.20170102.11
T2  - Pharmaceutical Science and Technology
JF  - Pharmaceutical Science and Technology
JO  - Pharmaceutical Science and Technology
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EP  - 19
PB  - Science Publishing Group
SN  - 2640-4540
UR  - https://doi.org/10.11648/j.pst.20170102.11
AB  - According to the World Health Report, approximately 450 million people suffer from a mental or behavioral disorder. This amounts of 12.3% of the global burden of disease, and will rise to 15% by 2020. Depression is most prevalent mental disorder and it is recognized to be symptomatically, psychologically and biologically heterogeneous. The crude methanolic extract of Acacia nilotica bark with different soluble partitionates were subjected to investigate for the evaluation of analgesic, hypoglycemic, CNS depressant and antidiarrheal activity on mice and thrombolytic, antihelmentic, antimicrobial, antioxidant along with cytotoxicity different in vivo experiment. The crude methanolic extract of bark of Acacia nilotica were evaluated for antidepressant activity showed insignificant value.
VL  - 1
IS  - 2
ER  -

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Author Information

Md. Mamun-Or-Rashid

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh
Muhammad Ashiqul Islam

Department of Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh
Taniya Idris

Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh
Md. Shah Amran

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh

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APA Style

Md. Mamun-Or-Rashid, Muhammad Ashiqul Islam, Taniya Idris, Md. Shah Amran. (2017). CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica. Pharmaceutical Science and Technology, 1(2), 13-19. https://doi.org/10.11648/j.pst.20170102.11

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ACS Style

Md. Mamun-Or-Rashid; Muhammad Ashiqul Islam; Taniya Idris; Md. Shah Amran. CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica. Pharm. Sci. Technol. 2017, 1(2), 13-19. doi: 10.11648/j.pst.20170102.11

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AMA Style

Md. Mamun-Or-Rashid, Muhammad Ashiqul Islam, Taniya Idris, Md. Shah Amran. CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica. Pharm Sci Technol. 2017;1(2):13-19. doi: 10.11648/j.pst.20170102.11

Copy | Download

@article{10.11648/j.pst.20170102.11,
  author = {Md. Mamun-Or-Rashid and Muhammad Ashiqul Islam and Taniya Idris and Md. Shah Amran},
  title = {CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica},
  journal = {Pharmaceutical Science and Technology},
  volume = {1},
  number = {2},
  pages = {13-19},
  doi = {10.11648/j.pst.20170102.11},
  url = {https://doi.org/10.11648/j.pst.20170102.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.pst.20170102.11},
  abstract = {According to the World Health Report, approximately 450 million people suffer from a mental or behavioral disorder. This amounts of 12.3% of the global burden of disease, and will rise to 15% by 2020. Depression is most prevalent mental disorder and it is recognized to be symptomatically, psychologically and biologically heterogeneous. The crude methanolic extract of Acacia nilotica bark with different soluble partitionates were subjected to investigate for the evaluation of analgesic, hypoglycemic, CNS depressant and antidiarrheal activity on mice and thrombolytic, antihelmentic, antimicrobial, antioxidant along with cytotoxicity different in vivo experiment. The crude methanolic extract of bark of Acacia nilotica were evaluated for antidepressant activity showed insignificant value.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica
AU  - Md. Mamun-Or-Rashid
AU  - Muhammad Ashiqul Islam
AU  - Taniya Idris
AU  - Md. Shah Amran
Y1  - 2017/08/16
PY  - 2017
N1  - https://doi.org/10.11648/j.pst.20170102.11
DO  - 10.11648/j.pst.20170102.11
T2  - Pharmaceutical Science and Technology
JF  - Pharmaceutical Science and Technology
JO  - Pharmaceutical Science and Technology
SP  - 13
EP  - 19
PB  - Science Publishing Group
SN  - 2640-4540
UR  - https://doi.org/10.11648/j.pst.20170102.11
AB  - According to the World Health Report, approximately 450 million people suffer from a mental or behavioral disorder. This amounts of 12.3% of the global burden of disease, and will rise to 15% by 2020. Depression is most prevalent mental disorder and it is recognized to be symptomatically, psychologically and biologically heterogeneous. The crude methanolic extract of Acacia nilotica bark with different soluble partitionates were subjected to investigate for the evaluation of analgesic, hypoglycemic, CNS depressant and antidiarrheal activity on mice and thrombolytic, antihelmentic, antimicrobial, antioxidant along with cytotoxicity different in vivo experiment. The crude methanolic extract of bark of Acacia nilotica were evaluated for antidepressant activity showed insignificant value.
VL  - 1
IS  - 2
ER  -

Copy | Download