Trichomonas vaginalis resistance to conventional antibiotics justifies the need to explore alternative remedies from medicinal plants since they represent a rich source of antiparasitic agents. This research was aimed to determine the inhibitory activities of two medicinal plants (S. longepedunculata and S. occidentalis) used to treat parasitic infections amongst the tribes of northern Nigeria. In the present study, extracts of the plants were obtained using maceration method, and their growth inhibitory activity against Trichomonas vaginalis evaluated in vitro. The extracts from the two plants revealed varied antiparasitic activities against the test organisms. The aqueous root extracts of the plants generally demonstrated higher growth inhibitory activity at 50 and 25mg/ml concentrations, while the least activity of the aqueous roots extracts were at lower concentration of 3.125mg/ml. The maximum antiparasitic activity was recorded for the aqueous root extract of S. synergistically against T. vaginalis. (Growth inhibition = 99.15%GI) at 50mg/ml. Findings from the statistical analysis, the result revealed significant difference (P<0.05) between S. and S. occidentalis. However, the result revealed significant difference (P<0.001), between the whole group of the aqueous root extracts with the negative control, and no significant difference among the other group of the aqueous roots extracts, The result presents the basis for which these plants have been used for treatment of Trichomonas vaginalis infections in traditional medicine. Results obtained suggest potential of the plants in the search for novel antiparasitic agents. Based on the findings from the current studies, the following suggestions are recommended: further researches should focus on other STI of medical importance such as Gonorrhea, Chlamydia, and Syphilis, and also research should be geared toward isolating active chemical component(s) and elucidate their exact mechanism(s) of action, safety margin and efficacy, Conservation of S. and S. occidentalis biodiversity should be also an important aspect to ensure sustainable availability of the plant.
| Published in | International Journal of Ecotoxicology and Ecobiology (Volume 2, Issue 1) |
| DOI | 10.11648/j.ijee.20170201.16 |
| Page(s) | 45-51 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Anti-parasitic Activities, S. longepedunculaat, S. occidentalis, T. vaginalis
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APA Style
Imam T. S., Abdullahi M. M., Dabo. N. T. (2017). Comparative Study on the Anti-Parasitic Activities of Securidaca and Senna occidentalis Root Extracts Against Trichomonas vaginalis. International Journal of Ecotoxicology and Ecobiology, 2(1), 45-51. https://doi.org/10.11648/j.ijee.20170201.16
ACS Style
Imam T. S.; Abdullahi M. M.; Dabo. N. T. Comparative Study on the Anti-Parasitic Activities of Securidaca and Senna occidentalis Root Extracts Against Trichomonas vaginalis. Int. J. Ecotoxicol. Ecobiol. 2017, 2(1), 45-51. doi: 10.11648/j.ijee.20170201.16
AMA Style
Imam T. S., Abdullahi M. M., Dabo. N. T. Comparative Study on the Anti-Parasitic Activities of Securidaca and Senna occidentalis Root Extracts Against Trichomonas vaginalis. Int J Ecotoxicol Ecobiol. 2017;2(1):45-51. doi: 10.11648/j.ijee.20170201.16
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Download@article{10.11648/j.ijee.20170201.16,
author = {Imam T. S. and Abdullahi M. M. and Dabo. N. T.},
title = {Comparative Study on the Anti-Parasitic Activities of Securidaca and Senna occidentalis Root Extracts Against Trichomonas vaginalis},
journal = {International Journal of Ecotoxicology and Ecobiology},
volume = {2},
number = {1},
pages = {45-51},
doi = {10.11648/j.ijee.20170201.16},
url = {https://doi.org/10.11648/j.ijee.20170201.16},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijee.20170201.16},
abstract = {Trichomonas vaginalis resistance to conventional antibiotics justifies the need to explore alternative remedies from medicinal plants since they represent a rich source of antiparasitic agents. This research was aimed to determine the inhibitory activities of two medicinal plants (S. longepedunculata and S. occidentalis) used to treat parasitic infections amongst the tribes of northern Nigeria. In the present study, extracts of the plants were obtained using maceration method, and their growth inhibitory activity against Trichomonas vaginalis evaluated in vitro. The extracts from the two plants revealed varied antiparasitic activities against the test organisms. The aqueous root extracts of the plants generally demonstrated higher growth inhibitory activity at 50 and 25mg/ml concentrations, while the least activity of the aqueous roots extracts were at lower concentration of 3.125mg/ml. The maximum antiparasitic activity was recorded for the aqueous root extract of S. synergistically against T. vaginalis. (Growth inhibition = 99.15%GI) at 50mg/ml. Findings from the statistical analysis, the result revealed significant difference (PS. and S. occidentalis. However, the result revealed significant difference (PTrichomonas vaginalis infections in traditional medicine. Results obtained suggest potential of the plants in the search for novel antiparasitic agents. Based on the findings from the current studies, the following suggestions are recommended: further researches should focus on other STI of medical importance such as Gonorrhea, Chlamydia, and Syphilis, and also research should be geared toward isolating active chemical component(s) and elucidate their exact mechanism(s) of action, safety margin and efficacy, Conservation of S. and S. occidentalis biodiversity should be also an important aspect to ensure sustainable availability of the plant.},
year = {2017}
}
TY - JOUR T1 - Comparative Study on the Anti-Parasitic Activities of Securidaca and Senna occidentalis Root Extracts Against Trichomonas vaginalis AU - Imam T. S. AU - Abdullahi M. M. AU - Dabo. N. T. Y1 - 2017/03/01 PY - 2017 N1 - https://doi.org/10.11648/j.ijee.20170201.16 DO - 10.11648/j.ijee.20170201.16 T2 - International Journal of Ecotoxicology and Ecobiology JF - International Journal of Ecotoxicology and Ecobiology JO - International Journal of Ecotoxicology and Ecobiology SP - 45 EP - 51 PB - Science Publishing Group SN - 2575-1735 UR - https://doi.org/10.11648/j.ijee.20170201.16 AB - Trichomonas vaginalis resistance to conventional antibiotics justifies the need to explore alternative remedies from medicinal plants since they represent a rich source of antiparasitic agents. This research was aimed to determine the inhibitory activities of two medicinal plants (S. longepedunculata and S. occidentalis) used to treat parasitic infections amongst the tribes of northern Nigeria. In the present study, extracts of the plants were obtained using maceration method, and their growth inhibitory activity against Trichomonas vaginalis evaluated in vitro. The extracts from the two plants revealed varied antiparasitic activities against the test organisms. The aqueous root extracts of the plants generally demonstrated higher growth inhibitory activity at 50 and 25mg/ml concentrations, while the least activity of the aqueous roots extracts were at lower concentration of 3.125mg/ml. The maximum antiparasitic activity was recorded for the aqueous root extract of S. synergistically against T. vaginalis. (Growth inhibition = 99.15%GI) at 50mg/ml. Findings from the statistical analysis, the result revealed significant difference (PS. and S. occidentalis. However, the result revealed significant difference (PTrichomonas vaginalis infections in traditional medicine. Results obtained suggest potential of the plants in the search for novel antiparasitic agents. Based on the findings from the current studies, the following suggestions are recommended: further researches should focus on other STI of medical importance such as Gonorrhea, Chlamydia, and Syphilis, and also research should be geared toward isolating active chemical component(s) and elucidate their exact mechanism(s) of action, safety margin and efficacy, Conservation of S. and S. occidentalis biodiversity should be also an important aspect to ensure sustainable availability of the plant. VL - 2 IS - 1 ER -
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