International Journal of Ecotoxicology and Ecobiology

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Optimization of Diagnosis and Treatment of Lactose Intolerance in Infants

Received: 29 October 2018    Accepted: 13 November 2018    Published: 26 February 2019
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Abstract

The paper presents the results of a study of the Benedict test for deciding the diagnosis of lactose intolerance in children and the effectiveness of lactase drugs. Benedict test is one of the standard methods for the diagnosis of lactose intolerance in children. Drugs with lactase enzyme that helps break down lactose (hydrolysis) into two simple sugars, glucose and galactose, which simplifies digestion. Lactase drugs has been shown to be the best way to preserve natural feeding in children with lactose intolerance, since the lactase composition is involved in the breakdown and absorption of carbohydrates and proteins, produce essential vitamins for improving the health and immunity of the child, normalize the composition of the intestinal flora. The use of mothers in the diet of easily digestible carbohydrates significantly increases the lactose content in breast milk, significantly increases the risk of developing lactose intolerance in children. When coprological study noted the disappearance of signs of excessive fermentation. It is shown that lactase drugs is an innovative and effective solution to lactose intolerance, the best way to preserve the natural feeding of children with lactose intolerance, as it reduces the load on the intestinal mucosa, preventing the development of characteristic symptoms of lactose intolerance in infants.

DOI 10.11648/j.ijee.20180304.11
Published in International Journal of Ecotoxicology and Ecobiology (Volume 3, Issue 4, December 2018)
Page(s) 73-77
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Lactose, Lactase, Lactose Intolerance, Lactose Resistance, Lactase Deficiency, Benedict Test, Diarrhea, Flatulence

References
[1] Brand Miller J, McVeagh P. Human milk oligosaccharides: 130 reasons to breast-feed. Br J Nutr. 1999; 82: 333–5.
[2] Berni Canani R, Passariello A, Buccigrossi V, Terrin G, Guarino A. The nutritional modulation of the evolving intestine. J Clin Gastroenterol. 2008; 42(Suppl 3): S197–200.
[3] Cox, M.; Nelson, D. Lehninger Principles of Biochemistry 3rd ed. Worth Publishers, 2000.
[4] “Living with lactose intolerance: If you take some simple steps, you can continue to enjoy a variety of dietary favorites” Ebony Oct. 2002 v57 i12 p66.
[5] Mattar, R., D. F. de Campos Mazo, and F. J. Carrilho, Lactose intolerance: diagnosis, genetic, and clinical factors. Clin Exp Gastroenterol, 2012. 5: p. 113-21.
[6] Krasinski, S.; Lee, M. “Human Adult-Onset Lactase Decline: An Update” Nutrition Reviews v.56 (1) Jan. 1988.
[7] MacGillivray S, Fahey T, McGuire W. Lactose avoidance for young children with acute diarrhoea. Cochrane Database Syst Rev. 2013; 10: CD005433.
[8] Stepahno Guandalini, Anil Dhawan, David Branski. Textbook of Pediatric Gastroenterology, Hepatology and Nutrition. A Comprehensive Guide to practice. 2016: 2015939902.
[9] Mattos AP, Ribeiro TC, Mendes PS, Valois SS, Mendes CM, Ribeiro HC Jr. Comparison of yogurt, soybean, casein, and amino acid-based diets in children with persistent diarrhea. Nutr Res. 2009; 29: 462–9.
[10] Olafsdottir E, Aksnes L, Fluge G, Berstad A. Faecal calprotectin levels in infants with infantile colic, healthy infants, children with inflammatory bowel disease, children with recurrent abdominal pain and healthy children. Acta Paediatr. 2002; 91: 45–50.
[11] de Vrese M, Stegelmann A, Richter B, Fenselau S, Laue C, Schrezenmeir J. Probiotics—compensation for lactase insufficiency. Am J Clin Nutr. 2001; 73(2 Suppl): 421S–9S.
[12] Studenikin B. M., Tursunxujayeva S. Sh., Lactase intolerance. № 1. — С. 28–30.
[13] USMLE, Kaplan/ Biochemistry and Medical Genetics/ Step 1, Lecture Notes 2018. Chapter 12, p190-198.
[14] Jose M Moreno-Villares, Isabel Polanco. Paediatric gastroenterology. An atlas of investigation and management. Clinical publishing. Oxford. Atlas Medical Publishing Ltd 2009. p50-58.
Author Information
  • Department of Children’s Disease №2, Tashkent Medical Academy, Tashkent, Uzbekistan

  • Department of Normal and Pathologic Physiology, Tashkent Medical Academy, Tashkent, Uzbekistan

  • Department of Children’s Disease №2, Tashkent Medical Academy, Tashkent, Uzbekistan

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  • APA Style

    Noila Tolipova, Sevara Azimova, Dilorom Ataeva. (2019). Optimization of Diagnosis and Treatment of Lactose Intolerance in Infants. International Journal of Ecotoxicology and Ecobiology, 3(4), 73-77. https://doi.org/10.11648/j.ijee.20180304.11

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    ACS Style

    Noila Tolipova; Sevara Azimova; Dilorom Ataeva. Optimization of Diagnosis and Treatment of Lactose Intolerance in Infants. Int. J. Ecotoxicol. Ecobiol. 2019, 3(4), 73-77. doi: 10.11648/j.ijee.20180304.11

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    AMA Style

    Noila Tolipova, Sevara Azimova, Dilorom Ataeva. Optimization of Diagnosis and Treatment of Lactose Intolerance in Infants. Int J Ecotoxicol Ecobiol. 2019;3(4):73-77. doi: 10.11648/j.ijee.20180304.11

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  • @article{10.11648/j.ijee.20180304.11,
      author = {Noila Tolipova and Sevara Azimova and Dilorom Ataeva},
      title = {Optimization of Diagnosis and Treatment of Lactose Intolerance in Infants},
      journal = {International Journal of Ecotoxicology and Ecobiology},
      volume = {3},
      number = {4},
      pages = {73-77},
      doi = {10.11648/j.ijee.20180304.11},
      url = {https://doi.org/10.11648/j.ijee.20180304.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijee.20180304.11},
      abstract = {The paper presents the results of a study of the Benedict test for deciding the diagnosis of lactose intolerance in children and the effectiveness of lactase drugs. Benedict test is one of the standard methods for the diagnosis of lactose intolerance in children. Drugs with lactase enzyme that helps break down lactose (hydrolysis) into two simple sugars, glucose and galactose, which simplifies digestion. Lactase drugs has been shown to be the best way to preserve natural feeding in children with lactose intolerance, since the lactase composition is involved in the breakdown and absorption of carbohydrates and proteins, produce essential vitamins for improving the health and immunity of the child, normalize the composition of the intestinal flora. The use of mothers in the diet of easily digestible carbohydrates significantly increases the lactose content in breast milk, significantly increases the risk of developing lactose intolerance in children. When coprological study noted the disappearance of signs of excessive fermentation. It is shown that lactase drugs is an innovative and effective solution to lactose intolerance, the best way to preserve the natural feeding of children with lactose intolerance, as it reduces the load on the intestinal mucosa, preventing the development of characteristic symptoms of lactose intolerance in infants.},
     year = {2019}
    }
    

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    AB  - The paper presents the results of a study of the Benedict test for deciding the diagnosis of lactose intolerance in children and the effectiveness of lactase drugs. Benedict test is one of the standard methods for the diagnosis of lactose intolerance in children. Drugs with lactase enzyme that helps break down lactose (hydrolysis) into two simple sugars, glucose and galactose, which simplifies digestion. Lactase drugs has been shown to be the best way to preserve natural feeding in children with lactose intolerance, since the lactase composition is involved in the breakdown and absorption of carbohydrates and proteins, produce essential vitamins for improving the health and immunity of the child, normalize the composition of the intestinal flora. The use of mothers in the diet of easily digestible carbohydrates significantly increases the lactose content in breast milk, significantly increases the risk of developing lactose intolerance in children. When coprological study noted the disappearance of signs of excessive fermentation. It is shown that lactase drugs is an innovative and effective solution to lactose intolerance, the best way to preserve the natural feeding of children with lactose intolerance, as it reduces the load on the intestinal mucosa, preventing the development of characteristic symptoms of lactose intolerance in infants.
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