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International Journal of Bioorganic Chemistry

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Design, Synthesis of New Amino Acid Derivatives and Evaluate DNA Binding Activity, Anticancer and Antimicrobial Activity

Ahmed A. Elhenawy
Received: 23 December 2016    Accepted: 10 January 2017    Published: 2 March 2017
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Abstract

The present review covers the recent synthetic amino acid derivatives with chemical transformations to peptide derivatives. The amino acids were used as starting keys for synthesis peptides and pseudopeptides derived from pyridinine, coumarine, imaddizole, pyrazole phthalyl, qunolinine and sulfonamide rings. these biomolecules have diverse biological and pharmacological actions, as antimicrobial, anti-cancer targeting human carbonic anhydrase (CA) and DNA binding activities.

DOI 10.11648/j.ijbc.20170202.11
Published in International Journal of Bioorganic Chemistry (Volume 2, Issue 2, June 2017)
Page(s) 36-50
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

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Keywords

Amino Acid, DNA Binding, Anticancer, Antimicrobial

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    Ahmed A. Elhenawy. (2017). Design, Synthesis of New Amino Acid Derivatives and Evaluate DNA Binding Activity, Anticancer and Antimicrobial Activity. International Journal of Bioorganic Chemistry, 2(2), 36-50. https://doi.org/10.11648/j.ijbc.20170202.11

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    ACS Style

    Ahmed A. Elhenawy. Design, Synthesis of New Amino Acid Derivatives and Evaluate DNA Binding Activity, Anticancer and Antimicrobial Activity. Int. J. Bioorg. Chem. 2017, 2(2), 36-50. doi: 10.11648/j.ijbc.20170202.11

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    AMA Style

    Ahmed A. Elhenawy. Design, Synthesis of New Amino Acid Derivatives and Evaluate DNA Binding Activity, Anticancer and Antimicrobial Activity. Int J Bioorg Chem. 2017;2(2):36-50. doi: 10.11648/j.ijbc.20170202.11

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  • @article{10.11648/j.ijbc.20170202.11,
  author = {Ahmed A. Elhenawy},
  title = {Design, Synthesis of New Amino Acid Derivatives and Evaluate DNA Binding Activity, Anticancer and Antimicrobial Activity},
  journal = {International Journal of Bioorganic Chemistry},
  volume = {2},
  number = {2},
  pages = {36-50},
  doi = {10.11648/j.ijbc.20170202.11},
  url = {https://doi.org/10.11648/j.ijbc.20170202.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbc.20170202.11},
  abstract = {The present review covers the recent synthetic amino acid derivatives with chemical transformations to peptide derivatives. The amino acids were used as starting keys for synthesis peptides and pseudopeptides derived from pyridinine, coumarine, imaddizole, pyrazole phthalyl, qunolinine and sulfonamide rings. these biomolecules have diverse biological and pharmacological actions, as antimicrobial, anti-cancer targeting human carbonic anhydrase (CA) and DNA binding activities.},
 year = {2017}
}

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  • TY  - JOUR
T1  - Design, Synthesis of New Amino Acid Derivatives and Evaluate DNA Binding Activity, Anticancer and Antimicrobial Activity
AU  - Ahmed A. Elhenawy
Y1  - 2017/03/02
PY  - 2017
N1  - https://doi.org/10.11648/j.ijbc.20170202.11
DO  - 10.11648/j.ijbc.20170202.11
T2  - International Journal of Bioorganic Chemistry
JF  - International Journal of Bioorganic Chemistry
JO  - International Journal of Bioorganic Chemistry
SP  - 36
EP  - 50
PB  - Science Publishing Group
SN  - 2578-9392
UR  - https://doi.org/10.11648/j.ijbc.20170202.11
AB  - The present review covers the recent synthetic amino acid derivatives with chemical transformations to peptide derivatives. The amino acids were used as starting keys for synthesis peptides and pseudopeptides derived from pyridinine, coumarine, imaddizole, pyrazole phthalyl, qunolinine and sulfonamide rings. these biomolecules have diverse biological and pharmacological actions, as antimicrobial, anti-cancer targeting human carbonic anhydrase (CA) and DNA binding activities.
VL  - 2
IS  - 2
ER  -

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Author Information

  • Ahmed A. Elhenawy

    Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt; Chemistry Department, Faculty of Science and Art, Al-Baha University, Al-Baha, Saudi Arabia

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