International Journal of Bioorganic Chemistry

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Interaction Between Chitosan Solutions, Cellulose Carriers and Some of the Multi-enzyme Complexes

Received: 30 January 2017    Accepted: 22 February 2017    Published: 09 March 2017
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Abstract

This research is devoted to create and investigate the wound healing medical materials that contain proteolytic enzymes. The aim of the study is to propose a new wound dressing design “Multiferm”TM, that is based on modified cellulose, chitosan gel and proteolytic enzymes, and represent the interaction between all of the drug components for the wound treatment such as: chitosan, modified cellulose (dialdehyde cellulose, cellulose phosphor ester) and different polyenzyme complexes (proteolytic complex from hepatopancreas of crab and bromelain). The research will also propose the scheme of the obtained materials and the components interaction mechanism. This scheme is supposed to create new materials with the special properties such as: minimal loss of biological activity during the process of dressings', obtaining, and using; minimal doze of therapeutic agent; and controlled drug release. The article and the results might be useful for everyone who is interested in cellulose chemistry, properties of proteolytic enzymes and drug development for wound healing.

DOI 10.11648/j.ijbc.20170202.12
Published in International Journal of Bioorganic Chemistry (Volume 2, Issue 2, June 2017)
Page(s) 51-60
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Chitosan, Dialdehyde Cellulose, Proteolytic Enzymes, Wound Healing, Drug Design, Controlled Release

References
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Author Information
  • Department of Biotechnology, Mendeleev University of Chemical Technology of Russia, Moscow, Russia

  • Department of Biotechnology, Mendeleev University of Chemical Technology of Russia, Moscow, Russia; Research Institute of Textile Materials, Moscow, Russia

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    Elina Eldarovna Dosadina, Alexey Alexeevich Belov. (2017). Interaction Between Chitosan Solutions, Cellulose Carriers and Some of the Multi-enzyme Complexes. International Journal of Bioorganic Chemistry, 2(2), 51-60. https://doi.org/10.11648/j.ijbc.20170202.12

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    ACS Style

    Elina Eldarovna Dosadina; Alexey Alexeevich Belov. Interaction Between Chitosan Solutions, Cellulose Carriers and Some of the Multi-enzyme Complexes. Int. J. Bioorg. Chem. 2017, 2(2), 51-60. doi: 10.11648/j.ijbc.20170202.12

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    AMA Style

    Elina Eldarovna Dosadina, Alexey Alexeevich Belov. Interaction Between Chitosan Solutions, Cellulose Carriers and Some of the Multi-enzyme Complexes. Int J Bioorg Chem. 2017;2(2):51-60. doi: 10.11648/j.ijbc.20170202.12

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  • @article{10.11648/j.ijbc.20170202.12,
      author = {Elina Eldarovna Dosadina and Alexey Alexeevich Belov},
      title = {Interaction Between Chitosan Solutions, Cellulose Carriers and Some of the Multi-enzyme Complexes},
      journal = {International Journal of Bioorganic Chemistry},
      volume = {2},
      number = {2},
      pages = {51-60},
      doi = {10.11648/j.ijbc.20170202.12},
      url = {https://doi.org/10.11648/j.ijbc.20170202.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijbc.20170202.12},
      abstract = {This research is devoted to create and investigate the wound healing medical materials that contain proteolytic enzymes. The aim of the study is to propose a new wound dressing design “Multiferm”TM, that is based on modified cellulose, chitosan gel and proteolytic enzymes, and represent the interaction between all of the drug components for the wound treatment such as: chitosan, modified cellulose (dialdehyde cellulose, cellulose phosphor ester) and different polyenzyme complexes (proteolytic complex from hepatopancreas of crab and bromelain). The research will also propose the scheme of the obtained materials and the components interaction mechanism. This scheme is supposed to create new materials with the special properties such as: minimal loss of biological activity during the process of dressings', obtaining, and using; minimal doze of therapeutic agent; and controlled drug release. The article and the results might be useful for everyone who is interested in cellulose chemistry, properties of proteolytic enzymes and drug development for wound healing.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Interaction Between Chitosan Solutions, Cellulose Carriers and Some of the Multi-enzyme Complexes
    AU  - Elina Eldarovna Dosadina
    AU  - Alexey Alexeevich Belov
    Y1  - 2017/03/09
    PY  - 2017
    N1  - https://doi.org/10.11648/j.ijbc.20170202.12
    DO  - 10.11648/j.ijbc.20170202.12
    T2  - International Journal of Bioorganic Chemistry
    JF  - International Journal of Bioorganic Chemistry
    JO  - International Journal of Bioorganic Chemistry
    SP  - 51
    EP  - 60
    PB  - Science Publishing Group
    SN  - 2578-9392
    UR  - https://doi.org/10.11648/j.ijbc.20170202.12
    AB  - This research is devoted to create and investigate the wound healing medical materials that contain proteolytic enzymes. The aim of the study is to propose a new wound dressing design “Multiferm”TM, that is based on modified cellulose, chitosan gel and proteolytic enzymes, and represent the interaction between all of the drug components for the wound treatment such as: chitosan, modified cellulose (dialdehyde cellulose, cellulose phosphor ester) and different polyenzyme complexes (proteolytic complex from hepatopancreas of crab and bromelain). The research will also propose the scheme of the obtained materials and the components interaction mechanism. This scheme is supposed to create new materials with the special properties such as: minimal loss of biological activity during the process of dressings', obtaining, and using; minimal doze of therapeutic agent; and controlled drug release. The article and the results might be useful for everyone who is interested in cellulose chemistry, properties of proteolytic enzymes and drug development for wound healing.
    VL  - 2
    IS  - 2
    ER  - 

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