International Journal of Food Science and Biotechnology

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Toxic Effects of Coralene Red XF and Remazol Red RR Textile Dyes on Liver and Kidney in Mice

Received: 18 June 2017    Accepted: 29 June 2017    Published: 31 July 2017
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Abstract

Adulterated food is a silent killer. Dishonest traders used textile dyes as adulterant in different foods as unethical practices. Moreover, textile industries also throw waste dye as effluent in ground water. In this study, we investigated the toxic effects of two textile dyes Coralene Red XF and Remazol Red RR by in vivo experiments in mice. Mice were administered Coralene Red XF and Remazol Red RR textile dyes at a single oral dose of 0.04g/kg daily for 21 days to observe any toxic effect of those dyes in mice. The toxic effects were evaluated by measuring the serum activity of aspartate amino-transferase (AST), glutamate pyruvate transaminase (ALT), serum total bilirubin (STBI), serum creatinine (SCR), serum urea (SUR) and histopathology of liver and kidney. The levels of AST, ALT, STBI, SUR and SCR were found to be increased by both Coralene Red XF and Remazol Red RR. Histopathological examination of liver showed inflammatory atypia of hepatocytes and inflamation also observed in kidney.

DOI 10.11648/j.ijfsb.20170203.14
Published in International Journal of Food Science and Biotechnology (Volume 2, Issue 3, August 2017)
Page(s) 97-102
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

In vivo, Textile Dyes, Coralene Red XF, Remazol Red RR, Toxicity

References
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Author Information
  • Department of Chemistry, Bangladesh University of Textiles, Dhaka, Bangladesh

  • Department of Chemistry, Bangladesh University of Textiles, Dhaka, Bangladesh

  • Department of Pathology, Bangladesh Sheikh Mujib Medical University, Dhaka, Bangladesh

  • Centre for Advanced Research in Sciences, University of Dhaka, Dhaka, Bangladesh

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    Mohammad Farhadur Rahman, Nargish Jahan Ara, Bishnu Pada Dey, Mohammad Zakir Sultan. (2017). Toxic Effects of Coralene Red XF and Remazol Red RR Textile Dyes on Liver and Kidney in Mice. International Journal of Food Science and Biotechnology, 2(3), 97-102. https://doi.org/10.11648/j.ijfsb.20170203.14

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    ACS Style

    Mohammad Farhadur Rahman; Nargish Jahan Ara; Bishnu Pada Dey; Mohammad Zakir Sultan. Toxic Effects of Coralene Red XF and Remazol Red RR Textile Dyes on Liver and Kidney in Mice. Int. J. Food Sci. Biotechnol. 2017, 2(3), 97-102. doi: 10.11648/j.ijfsb.20170203.14

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    AMA Style

    Mohammad Farhadur Rahman, Nargish Jahan Ara, Bishnu Pada Dey, Mohammad Zakir Sultan. Toxic Effects of Coralene Red XF and Remazol Red RR Textile Dyes on Liver and Kidney in Mice. Int J Food Sci Biotechnol. 2017;2(3):97-102. doi: 10.11648/j.ijfsb.20170203.14

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  • @article{10.11648/j.ijfsb.20170203.14,
      author = {Mohammad Farhadur Rahman and Nargish Jahan Ara and Bishnu Pada Dey and Mohammad Zakir Sultan},
      title = {Toxic Effects of Coralene Red XF and Remazol Red RR Textile Dyes on Liver and Kidney in Mice},
      journal = {International Journal of Food Science and Biotechnology},
      volume = {2},
      number = {3},
      pages = {97-102},
      doi = {10.11648/j.ijfsb.20170203.14},
      url = {https://doi.org/10.11648/j.ijfsb.20170203.14},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijfsb.20170203.14},
      abstract = {Adulterated food is a silent killer. Dishonest traders used textile dyes as adulterant in different foods as unethical practices. Moreover, textile industries also throw waste dye as effluent in ground water. In this study, we investigated the toxic effects of two textile dyes Coralene Red XF and Remazol Red RR by in vivo experiments in mice. Mice were administered Coralene Red XF and Remazol Red RR textile dyes at a single oral dose of 0.04g/kg daily for 21 days to observe any toxic effect of those dyes in mice. The toxic effects were evaluated by measuring the serum activity of aspartate amino-transferase (AST), glutamate pyruvate transaminase (ALT), serum total bilirubin (STBI), serum creatinine (SCR), serum urea (SUR) and histopathology of liver and kidney. The levels of AST, ALT, STBI, SUR and SCR were found to be increased by both Coralene Red XF and Remazol Red RR. Histopathological examination of liver showed inflammatory atypia of hepatocytes and inflamation also observed in kidney.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Toxic Effects of Coralene Red XF and Remazol Red RR Textile Dyes on Liver and Kidney in Mice
    AU  - Mohammad Farhadur Rahman
    AU  - Nargish Jahan Ara
    AU  - Bishnu Pada Dey
    AU  - Mohammad Zakir Sultan
    Y1  - 2017/07/31
    PY  - 2017
    N1  - https://doi.org/10.11648/j.ijfsb.20170203.14
    DO  - 10.11648/j.ijfsb.20170203.14
    T2  - International Journal of Food Science and Biotechnology
    JF  - International Journal of Food Science and Biotechnology
    JO  - International Journal of Food Science and Biotechnology
    SP  - 97
    EP  - 102
    PB  - Science Publishing Group
    SN  - 2578-9643
    UR  - https://doi.org/10.11648/j.ijfsb.20170203.14
    AB  - Adulterated food is a silent killer. Dishonest traders used textile dyes as adulterant in different foods as unethical practices. Moreover, textile industries also throw waste dye as effluent in ground water. In this study, we investigated the toxic effects of two textile dyes Coralene Red XF and Remazol Red RR by in vivo experiments in mice. Mice were administered Coralene Red XF and Remazol Red RR textile dyes at a single oral dose of 0.04g/kg daily for 21 days to observe any toxic effect of those dyes in mice. The toxic effects were evaluated by measuring the serum activity of aspartate amino-transferase (AST), glutamate pyruvate transaminase (ALT), serum total bilirubin (STBI), serum creatinine (SCR), serum urea (SUR) and histopathology of liver and kidney. The levels of AST, ALT, STBI, SUR and SCR were found to be increased by both Coralene Red XF and Remazol Red RR. Histopathological examination of liver showed inflammatory atypia of hepatocytes and inflamation also observed in kidney.
    VL  - 2
    IS  - 3
    ER  - 

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