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Assessment of Metabolites Content of Native Alcoholic Beverages Obtained from Jos, Nigeria
International Journal of Food Science and Biotechnology
Volume 5, Issue 4, December 2020, Pages: 107-111
Received: Nov. 3, 2020; Accepted: Nov. 20, 2020; Published: Dec. 16, 2020
Volume 5, Issue 4, December 2020, Pages: 107-111
Received: Nov. 3, 2020; Accepted: Nov. 20, 2020; Published: Dec. 16, 2020
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Authors
Samuel Yusufu Gazuwa, Department of Biochemistry, College of Health Sciences, University of Jos, Jos, Nigeria
Jonathan Dingkwoet Dabak, Department of Biochemistry, College of Health Sciences, University of Jos, Jos, Nigeria
Kiri Hashimu Jaryum, Department of Biochemistry, College of Health Sciences, University of Jos, Jos, Nigeria
Segun Afolabi Olomu, Department of Biochemistry, College of Health Sciences, University of Jos, Jos, Nigeriasygazuwa@gmail.com
Abstract
Burukutu, (BKT) Pito (PT) and Goskolo (GSK) are drinks consumed routinely within the area of study. Although consumption of GSK is illegal owing to its life threatening toxicity, people still consume it secretly. Whereas BKT and PT are locally prepared using unscientific methods in preparing the drinks, GSK is a mixture containing different compounds and chemicals. BKT and PT are more commonly ingested than GSK. Because methods applied during ‘brewing’ BKT and PT are not scientific, toxic metabolites might be generated. So, the drinkers are prone to their toxic effects. This work ascertained the presence and levels of unwanted metabolites in these drinks using Gas chromatographic-Mass spectrometric (GC-MS) technique. Metabolites could aggravate the toxicity of alcohol and alcohol-related disease conditions. Results, (% relative abundance), showed the significant presence in BKTof6-Octadecanoic acid (38.51), Hexadecanoic acid (20.92), Isopentyl alcohol (12.27), 1,11,13-Octadecatriene (11.60) among others. In PT,9-Octadecanoic acid (39.40), Hexadecanoic acid (15.98), Carbonic acid methylpentyl ester (14.22), 9,17-Octadecadienal (6.37) were the major components. In GSK, 6-Octadecenoic acid (42.43), n-Hexadecanoic (17.51), 1-Butanol (16.52) 9 and 9,12-Octadecadienoic acid (10.72) were the dominant components. BKT, PT, and GSK are composed of compounds/metabolites that are organic in nature, with about 83% of them being organic acids. This leads to a decrease in pH thereby making the drinks acidic. It is concluded that the alcoholic beverages contain metabolites that predispose drinkers to metabolic or respiratory acidosis, due to drop in pH. Furthermore, these metabolites could aggravate the toxicity of alcohol. Other components of the samples include ketones, different types of alcohols, aldehydes, derivatives of benzene and esters.
Keywords
Organic, Metabolites, Acids, Burukutu, Pito, Goskolo, Toxic
To cite this article
Samuel Yusufu Gazuwa,
Jonathan Dingkwoet Dabak,
Kiri Hashimu Jaryum,
Segun Afolabi Olomu,
Assessment of Metabolites Content of Native Alcoholic Beverages Obtained from Jos, Nigeria, International Journal of Food Science and Biotechnology.
Vol. 5, No. 4,
2020, pp. 107-111.
doi: 10.11648/j.ijfsb.20200504.19
Copyright
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
[1]
Gazuwa, S. Y., Dabak, J. D., and Ubom G. A. (2006). Iron Contamination of Two Local Alcoholic Drinks. Journal of Medicinein the Tropics, 8 (1): 33-38.
[2]
Gazuwa, S. Y., Dabak, J. D., and Ubom, G. A. (2008). Contaminants in local alcoholic beverages: zinc and manganesecontamination. International Journal of Biological and Chemical Sciences2 (4): 411-416.
[3]
Solange, K. G, Fokou G, Dje, K. M., and Bonfoh B. (2014). Review on African traditional cereal beverages. American Journalof Research Communication; Vol 2 (5): 1-51.
[4]
Gazuwa, S. Y., and Denkok, Y. (2017). Organic Metabolites, alcohol content and Microbial Contaminants in Sorghum-basedNative Beers Consumed in Barkin Ladi Local Government Area, Nigeria. Journal of Scientific Research and Reports; 17 (4): 1-8. Article no, JSRR. 38124. ISSN: 2320-0227.
[5]
Adriana, J, Harald, J, Volker A., Stefan P. A. M. Fárr, L. H, and Schiopu, A. (2010). Volatile congeners in alcoholic beverages: analysis and forensic significance. Romanian Journal of Legal Medicine; (18): 26-270. DOI: 10.4323/rjlm.2010.265.
[6]
Kostrubsky V. E., Strom S. C. W, Wood, S. G, Wrighton, S. A, and Sinclair, J. F. (1995). Ethanol and isopentanol increase CYP3A and CYP2E in cultures of human hepatocytes. Arch Biochem Biophys; 2 (2): 516-520.
[7]
An, P., Mu, C., Rajiv, C., Jason H., Wu, Y., Qi, S, Hanna. C., Darush, M. and Frank B. H. (2012). α-Linolenic acid of CVDs: a systemic review and meta-analysis. The American Journal of Clinical Nutrition; 96 (6): 1262-1273.
[8]
Gazuwa, S. Y. (2014). Toxicants in native beers locally prepared within Jos metropolis. Doctor of Philosophy (Ph. D) thesis in Biochemistry, University of Jos, Nigeria.
[9]
United State Environmental Protection Agency (2005). Provisional peer reviewed toxicity values for Hexadecanoic acid. CASRN; 57: 10-13.
[10]
Segal D., Bale A. S., Philips L. J., Sasso A., Scholosser, P. M., Starkey, C. and Makris, S. L. (2020). Issues in assessing thehealth risks of n-Butanol. Journal of Applied Toxicology; 40 (1): 72-86.
[11]
Bloch, P., Kulig, A.; Paradowski M. and Wybrzak-Wrobel T. (1990). Toxicodynamics of benzene, ethyl alcohol and benzeneplus ethyl alcohol based on the histopathological examination of selected organs in rats. Pol J Occup Med; 3 (1): 69-82.
[12]
Giorgio M, Anna, F. C.; Teresa, C. and Lungi (2003). Prolonged ethanol ingestion enhances benzene myelotoxicity and lowersurinary concentration of benzene metabolites level in CD-1 male mice. Toxicological Sciences; 75 (1): 16-24.
[13]
MacKenzie, B. and Derek, J. S. (2020). Metabolic Acidosis. In: StatPearls [Internet]. Treasure Island (FL): StatPearlsPublishing; 2020 Jan. 2020 Jul 25.
[14]
Taofeek, O. A., Ganiyat, A. I., Oluwayemisi, B. O., Azeemat, T. A., Aisha, O. M. and Fausat L. K. (2014). Sorghum-basedalcoholic beverage, Burukutu perturbs the redox status of the liver of male rats. Food Sci Nutr; 2 (5): 591-596.
[15]
Akoh, C. C., and Min, D. B. “Food lipids: chemistry, nutrition, and biotechnology” 3rd ed. 2008, pp. 1-18.
[16]
Shanu, H., Lovely, G., Jata, S., Alok, K. G, and Pooja, V. (2020). c-9-hexadecenal, a natural compound targeting cell wallorganisation, critical growth factor & virulence of Aspergillus fumugatus. ACS Omega; 5 (17): 1007-10088.
[17]
Odetokun, S. M. (2006). Chemical and nutritive values of burukutu (a Nigerian beverage). Food and Nahrung; 41, (6): 1-3.
[18]
Aaron, N. A., Apori, N., and Samuel, A. B. (2014). Analysis of essential elements in pito—a cereal food drink and its brandsby the single-comparator method of neutron activation analysis. Food Sci Nutr; 2 (3): 230–235.
[19]
Taofeek, O. A., Ganiyat, A. I., Abdulwasiu, O. A., Folakemi, A. A., Shakirat, A. A., Simiat, M. O., Simiat, O. J, and Oyelolu (2014). Nutritional andantioxidantdispositions of sorghum/millet-based beverages indigenous to Nigeria. Food Sci Nutr; 2 (5): 597–604.
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