Optimizing the Effect of ω-3 Fatty Acids on the Lipid Profile in Metabolic Syndrome Patients

Ghada Mahmoud Khafagy; Mayssa Ebrahim Ali

doi:doi:10.11648/j.ejpm.20150306.13

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Optimizing the Effect of ω-3 Fatty Acids on the Lipid Profile in Metabolic Syndrome Patients

Ghada Mahmoud Khafagy, Mayssa Ebrahim Ali

Published in European Journal of Preventive Medicine (Volume 3, Issue 6)

Received: 4 August 2015 Accepted: 27 August 2015 Published: 3 November 2015

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Abstract

Background: The metabolic syndrome is a clustering of metabolic abnormalities and cardiovascular risk factors. It is vital to start the lifestyle interventions and treatment early in patients with metabolic syndrome to prevent the twin global epidemics of type 2diabetes and CVD. Objective: to investigate the overall effects of omega-3 fatty acids supplementation In addition to Dietary Approaches to Stop Hypertension (DASH) nutritional intervention on the lipid profile in patients with metabolic syndrome and to study if the addition of DASH diet will alleviate the rise in LDL- C that occurs with ω-3 fatty acid supplementation. Research design and methods: This was a prospective interventional outpatient trial conducted on 42 patients with the metabolic syndrome. They received ω-3 fatty acid supplementation 1 g/d in addition to DASH nutritional education for 12 weeks: the DASH diet with increased consumption of fruit, vegetables, low-fat dairy and whole grains and lower in saturated fat, total fat, and cholesterol. The main outcome measures were the lipid profile of the patients with metabolic syndrome. Results: ω-3 fatty acid together with The DASH diet significantly changed the mean of all parameters of lipid profile in metabolic syndrome patients. After 12 weeks, there was a significant increase in HDL-C (14%), significant reductions in TG (37.7%), LDL (29.4%) and a significant reduction in Non HDL-C (24.7%). Conclusion: this study demonstrated that the DASH diet optimizes and complements the effect of ω-3 fatty acid on the lipid profile of patients with metabolic syndrome by alleviating the rise in LDL- C that occurs with omega supplementation.

Published in	European Journal of Preventive Medicine (Volume 3, Issue 6)
DOI	10.11648/j.ejpm.20150306.13
Page(s)	180-183
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Hypertriglyceridemia, Omega-3 Fatty Acids, LDL, Metabolic Syndrome, DASH, LDL

References

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APA Style

Ghada Mahmoud Khafagy, Mayssa Ebrahim Ali. (2015). Optimizing the Effect of ω-3 Fatty Acids on the Lipid Profile in Metabolic Syndrome Patients. European Journal of Preventive Medicine, 3(6), 180-183. https://doi.org/10.11648/j.ejpm.20150306.13

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ACS Style

Ghada Mahmoud Khafagy; Mayssa Ebrahim Ali. Optimizing the Effect of ω-3 Fatty Acids on the Lipid Profile in Metabolic Syndrome Patients. Eur. J. Prev. Med. 2015, 3(6), 180-183. doi: 10.11648/j.ejpm.20150306.13

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AMA Style

Ghada Mahmoud Khafagy, Mayssa Ebrahim Ali. Optimizing the Effect of ω-3 Fatty Acids on the Lipid Profile in Metabolic Syndrome Patients. Eur J Prev Med. 2015;3(6):180-183. doi: 10.11648/j.ejpm.20150306.13

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@article{10.11648/j.ejpm.20150306.13,
  author = {Ghada Mahmoud Khafagy and Mayssa Ebrahim Ali},
  title = {Optimizing the Effect of ω-3 Fatty Acids on the Lipid Profile in Metabolic Syndrome Patients},
  journal = {European Journal of Preventive Medicine},
  volume = {3},
  number = {6},
  pages = {180-183},
  doi = {10.11648/j.ejpm.20150306.13},
  url = {https://doi.org/10.11648/j.ejpm.20150306.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejpm.20150306.13},
  abstract = {Background: The metabolic syndrome is a clustering of metabolic abnormalities and cardiovascular risk factors. It is vital to start the lifestyle interventions and treatment early in patients with metabolic syndrome to prevent the twin global epidemics of type 2diabetes and CVD. Objective: to investigate the overall effects of omega-3 fatty acids supplementation In addition to Dietary Approaches to Stop Hypertension (DASH) nutritional intervention on the lipid profile in patients with metabolic syndrome and to study if the addition of DASH diet will alleviate the rise in LDL- C that occurs with ω-3 fatty acid supplementation. Research design and methods: This was a prospective interventional outpatient trial conducted on 42 patients with the metabolic syndrome. They received ω-3 fatty acid supplementation 1 g/d in addition to DASH nutritional education for 12 weeks: the DASH diet with increased consumption of fruit, vegetables, low-fat dairy and whole grains and lower in saturated fat, total fat, and cholesterol. The main outcome measures were the lipid profile of the patients with metabolic syndrome. Results: ω-3 fatty acid together with The DASH diet significantly changed the mean of all parameters of lipid profile in metabolic syndrome patients. After 12 weeks, there was a significant increase in HDL-C (14%), significant reductions in TG (37.7%), LDL (29.4%) and a significant reduction in Non HDL-C (24.7%). Conclusion: this study demonstrated that the DASH diet optimizes and complements the effect of ω-3 fatty acid on the lipid profile of patients with metabolic syndrome by alleviating the rise in LDL- C that occurs with omega supplementation.},
 year = {2015}
}

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TY  - JOUR
T1  - Optimizing the Effect of ω-3 Fatty Acids on the Lipid Profile in Metabolic Syndrome Patients
AU  - Ghada Mahmoud Khafagy
AU  - Mayssa Ebrahim Ali
Y1  - 2015/11/03
PY  - 2015
N1  - https://doi.org/10.11648/j.ejpm.20150306.13
DO  - 10.11648/j.ejpm.20150306.13
T2  - European Journal of Preventive Medicine
JF  - European Journal of Preventive Medicine
JO  - European Journal of Preventive Medicine
SP  - 180
EP  - 183
PB  - Science Publishing Group
SN  - 2330-8230
UR  - https://doi.org/10.11648/j.ejpm.20150306.13
AB  - Background: The metabolic syndrome is a clustering of metabolic abnormalities and cardiovascular risk factors. It is vital to start the lifestyle interventions and treatment early in patients with metabolic syndrome to prevent the twin global epidemics of type 2diabetes and CVD. Objective: to investigate the overall effects of omega-3 fatty acids supplementation In addition to Dietary Approaches to Stop Hypertension (DASH) nutritional intervention on the lipid profile in patients with metabolic syndrome and to study if the addition of DASH diet will alleviate the rise in LDL- C that occurs with ω-3 fatty acid supplementation. Research design and methods: This was a prospective interventional outpatient trial conducted on 42 patients with the metabolic syndrome. They received ω-3 fatty acid supplementation 1 g/d in addition to DASH nutritional education for 12 weeks: the DASH diet with increased consumption of fruit, vegetables, low-fat dairy and whole grains and lower in saturated fat, total fat, and cholesterol. The main outcome measures were the lipid profile of the patients with metabolic syndrome. Results: ω-3 fatty acid together with The DASH diet significantly changed the mean of all parameters of lipid profile in metabolic syndrome patients. After 12 weeks, there was a significant increase in HDL-C (14%), significant reductions in TG (37.7%), LDL (29.4%) and a significant reduction in Non HDL-C (24.7%). Conclusion: this study demonstrated that the DASH diet optimizes and complements the effect of ω-3 fatty acid on the lipid profile of patients with metabolic syndrome by alleviating the rise in LDL- C that occurs with omega supplementation.
VL  - 3
IS  - 6
ER  -

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Author Information

Ghada Mahmoud Khafagy

Department of Family Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt
Mayssa Ebrahim Ali

Department of Internal Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt

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APA Style

Ghada Mahmoud Khafagy, Mayssa Ebrahim Ali. (2015). Optimizing the Effect of ω-3 Fatty Acids on the Lipid Profile in Metabolic Syndrome Patients. European Journal of Preventive Medicine, 3(6), 180-183. https://doi.org/10.11648/j.ejpm.20150306.13

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ACS Style

Ghada Mahmoud Khafagy; Mayssa Ebrahim Ali. Optimizing the Effect of ω-3 Fatty Acids on the Lipid Profile in Metabolic Syndrome Patients. Eur. J. Prev. Med. 2015, 3(6), 180-183. doi: 10.11648/j.ejpm.20150306.13

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AMA Style

Ghada Mahmoud Khafagy, Mayssa Ebrahim Ali. Optimizing the Effect of ω-3 Fatty Acids on the Lipid Profile in Metabolic Syndrome Patients. Eur J Prev Med. 2015;3(6):180-183. doi: 10.11648/j.ejpm.20150306.13

Copy | Download

@article{10.11648/j.ejpm.20150306.13,
  author = {Ghada Mahmoud Khafagy and Mayssa Ebrahim Ali},
  title = {Optimizing the Effect of ω-3 Fatty Acids on the Lipid Profile in Metabolic Syndrome Patients},
  journal = {European Journal of Preventive Medicine},
  volume = {3},
  number = {6},
  pages = {180-183},
  doi = {10.11648/j.ejpm.20150306.13},
  url = {https://doi.org/10.11648/j.ejpm.20150306.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejpm.20150306.13},
  abstract = {Background: The metabolic syndrome is a clustering of metabolic abnormalities and cardiovascular risk factors. It is vital to start the lifestyle interventions and treatment early in patients with metabolic syndrome to prevent the twin global epidemics of type 2diabetes and CVD. Objective: to investigate the overall effects of omega-3 fatty acids supplementation In addition to Dietary Approaches to Stop Hypertension (DASH) nutritional intervention on the lipid profile in patients with metabolic syndrome and to study if the addition of DASH diet will alleviate the rise in LDL- C that occurs with ω-3 fatty acid supplementation. Research design and methods: This was a prospective interventional outpatient trial conducted on 42 patients with the metabolic syndrome. They received ω-3 fatty acid supplementation 1 g/d in addition to DASH nutritional education for 12 weeks: the DASH diet with increased consumption of fruit, vegetables, low-fat dairy and whole grains and lower in saturated fat, total fat, and cholesterol. The main outcome measures were the lipid profile of the patients with metabolic syndrome. Results: ω-3 fatty acid together with The DASH diet significantly changed the mean of all parameters of lipid profile in metabolic syndrome patients. After 12 weeks, there was a significant increase in HDL-C (14%), significant reductions in TG (37.7%), LDL (29.4%) and a significant reduction in Non HDL-C (24.7%). Conclusion: this study demonstrated that the DASH diet optimizes and complements the effect of ω-3 fatty acid on the lipid profile of patients with metabolic syndrome by alleviating the rise in LDL- C that occurs with omega supplementation.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - Optimizing the Effect of ω-3 Fatty Acids on the Lipid Profile in Metabolic Syndrome Patients
AU  - Ghada Mahmoud Khafagy
AU  - Mayssa Ebrahim Ali
Y1  - 2015/11/03
PY  - 2015
N1  - https://doi.org/10.11648/j.ejpm.20150306.13
DO  - 10.11648/j.ejpm.20150306.13
T2  - European Journal of Preventive Medicine
JF  - European Journal of Preventive Medicine
JO  - European Journal of Preventive Medicine
SP  - 180
EP  - 183
PB  - Science Publishing Group
SN  - 2330-8230
UR  - https://doi.org/10.11648/j.ejpm.20150306.13
AB  - Background: The metabolic syndrome is a clustering of metabolic abnormalities and cardiovascular risk factors. It is vital to start the lifestyle interventions and treatment early in patients with metabolic syndrome to prevent the twin global epidemics of type 2diabetes and CVD. Objective: to investigate the overall effects of omega-3 fatty acids supplementation In addition to Dietary Approaches to Stop Hypertension (DASH) nutritional intervention on the lipid profile in patients with metabolic syndrome and to study if the addition of DASH diet will alleviate the rise in LDL- C that occurs with ω-3 fatty acid supplementation. Research design and methods: This was a prospective interventional outpatient trial conducted on 42 patients with the metabolic syndrome. They received ω-3 fatty acid supplementation 1 g/d in addition to DASH nutritional education for 12 weeks: the DASH diet with increased consumption of fruit, vegetables, low-fat dairy and whole grains and lower in saturated fat, total fat, and cholesterol. The main outcome measures were the lipid profile of the patients with metabolic syndrome. Results: ω-3 fatty acid together with The DASH diet significantly changed the mean of all parameters of lipid profile in metabolic syndrome patients. After 12 weeks, there was a significant increase in HDL-C (14%), significant reductions in TG (37.7%), LDL (29.4%) and a significant reduction in Non HDL-C (24.7%). Conclusion: this study demonstrated that the DASH diet optimizes and complements the effect of ω-3 fatty acid on the lipid profile of patients with metabolic syndrome by alleviating the rise in LDL- C that occurs with omega supplementation.
VL  - 3
IS  - 6
ER  -

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