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Alterations in Plasma Glucose Levels among Blood Donors

Received: 24 April 2014    Accepted: 13 May 2014    Published: 20 May 2014
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Abstract

Blood donors are required to meet several criteria which are intended to ensure that safe blood is made available for transfusion as well as keeping the donor safe. Plasma glucose levels may be altered immediately after blood donation. However, since plasma glucose testing is not part of the screening tests, individuals who may have low or high plasma glucose levels are likely to be passed fit to donate. This may be detrimental to their health. The objective of the study was to measure the random plasma glucose (RPG) levels in blood donors before and after donation and determine whether there is any significant change in their levels. Samples were obtained from the Accra Area Blood Centre (AABC) at the Korle-Bu teaching Hospital. Two hundred (200) subjects were recruited who were healthy individuals between the ages of 18-52 years who had satisfied the donor criteria set by the AABC. Pre-and-post donation RPG level for each sample was determined using the VitaLab Junior Selectra Clinical Chemistry analyzer. Majority of the subjects were in the age-range of 21-30 years and there were more males than females. The mean RPG concentration before donation was 5.70±2.24 mmol/l and 9.07±6.48 mmol/l afterwards. 95% confidence interval was used and the difference was statistically significant (p<0.001). The findings indicate that the level of RPG is altered (mostly elevated) after blood donation. Knowing pre-donation glucose levels may therefore be important in keeping the donor safe.

Published in European Journal of Preventive Medicine (Volume 2, Issue 2)
DOI 10.11648/j.ejpm.20140202.12
Page(s) 25-28
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Donor, Recipient, Plasma Glucose, Hyperglycaemia, Hypoglycaemia

References
[1] Alter HJ and Klein HG (2008). The hazards of blood transfusion in historical perspective. Society of Haematology 112: 2617 - 2626.
[2] Contreras M (1992). The blood donors and Tests on Donor blood. ABC of Transfusion. 2nd ed. Tavistock Square, London.
[3] World Health Organization (2011). Voluntary unpaid blood donations increase, saving more lives. World Blood Donor Day encouraging more people to become regular voluntary blood donors; www.who.int/../index.htm.
[4] World Health Organization (2011). Global database on Blood Safety summary report Geneva; www. who. nt/bloodsafety/global database /GDBS summary report 2011.pdf
[5] Harmening DM (1999). Donor Selection and Component Preparation by Wright PA: Modern Blood Banking and Transfusion Practices. 4th ed. F.A. Davis Company, Philadelphia.
[6] Canadian Diabetes Association (2010). Donating Blood. Updated July 4 2012; http//www.diabetes.co>Home>Diabetes and You.
[7] Facchini FS (1998). Effect of phlebotomy on plasma glucose and insulin concentrations. Diabetes Care Med 21 (12):2190.
[8] Garrioch MA (2004). The body’s response to blood loss. Vox Sanguinis 87: 74-76.
[9] National Diabetes Information Clearing House. Hypoglycaemia (2008). Updated November 6, 2012; http://www.diabetes.niddk.nih.gov/dm/pubs/hypo.
[10] American Diabetes Association. Hyperglycaemia (High blood glucose). Updated January 4, 2012; www.diabetes.org>Home>Livingwithdiabetes>
[11] Arronoff S (2004). Glucose metabolism and regulation: beyond insulin and glucagon. Diabetes Spectrum; 17:183-190.
[12] World Health Organization, WHO (2013). Blood safety and availability. Retrieved on July 26, 2013 from http://www.who.int/mediacentre/factsheets/fs279/en/
[13] The Ghanaian Times (2011). Korle-Bu Blood Bank besieged by contractors. Retrieved March 20 2013 from www.modernghana.com/news/327478/1/korle-bu-blood-bank-besieged-by-contractors.html
[14] Shrayyef M.Z. and Gerich J.E. (2010). Normal Glucose Homeostasis. Principles of Diabetes Mellitus. L. Poretsky (ed.), New York. 2: 1-32
[15] Sonksen P. and Sonksen J. (2000). Insulin: understanding its action in Health and disease. British Medical Journal 85(1): 69-79.
Cite This Article
  • APA Style

    Samuel Antwi-Baffour, Josephine Agyaa Yobo, Ransford Kyeremeh, John Tetteh, Richard Harry Asmah, et al. (2014). Alterations in Plasma Glucose Levels among Blood Donors. European Journal of Preventive Medicine, 2(2), 25-28. https://doi.org/10.11648/j.ejpm.20140202.12

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    ACS Style

    Samuel Antwi-Baffour; Josephine Agyaa Yobo; Ransford Kyeremeh; John Tetteh; Richard Harry Asmah, et al. Alterations in Plasma Glucose Levels among Blood Donors. Eur. J. Prev. Med. 2014, 2(2), 25-28. doi: 10.11648/j.ejpm.20140202.12

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    AMA Style

    Samuel Antwi-Baffour, Josephine Agyaa Yobo, Ransford Kyeremeh, John Tetteh, Richard Harry Asmah, et al. Alterations in Plasma Glucose Levels among Blood Donors. Eur J Prev Med. 2014;2(2):25-28. doi: 10.11648/j.ejpm.20140202.12

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  • @article{10.11648/j.ejpm.20140202.12,
      author = {Samuel Antwi-Baffour and Josephine Agyaa Yobo and Ransford Kyeremeh and John Tetteh and Richard Harry Asmah and Patrick Ayeh-Kumi},
      title = {Alterations in Plasma Glucose Levels among Blood Donors},
      journal = {European Journal of Preventive Medicine},
      volume = {2},
      number = {2},
      pages = {25-28},
      doi = {10.11648/j.ejpm.20140202.12},
      url = {https://doi.org/10.11648/j.ejpm.20140202.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejpm.20140202.12},
      abstract = {Blood donors are required to meet several criteria which are intended to ensure that safe blood is made available for transfusion as well as keeping the donor safe. Plasma glucose levels may be altered immediately after blood donation. However, since plasma glucose testing is not part of the screening tests, individuals who may have low or high plasma glucose levels are likely to be passed fit to donate. This may be detrimental to their health. The objective of the study was to measure the random plasma glucose (RPG) levels in blood donors before and after donation and determine whether there is any significant change in their levels. Samples were obtained from the Accra Area Blood Centre (AABC) at the Korle-Bu teaching Hospital. Two hundred (200) subjects were recruited who were healthy individuals between the ages of 18-52 years who had satisfied the donor criteria set by the AABC. Pre-and-post donation RPG level for each sample was determined using the VitaLab Junior Selectra Clinical Chemistry analyzer. Majority of the subjects were in the age-range of 21-30 years and there were more males than females. The mean RPG concentration before donation was 5.70±2.24 mmol/l and 9.07±6.48 mmol/l afterwards. 95% confidence interval was used and the difference was statistically significant (p<0.001). The findings indicate that the level of RPG is altered (mostly elevated) after blood donation. Knowing pre-donation glucose levels may therefore be important in keeping the donor safe.},
     year = {2014}
    }
    

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  • TY  - JOUR
    T1  - Alterations in Plasma Glucose Levels among Blood Donors
    AU  - Samuel Antwi-Baffour
    AU  - Josephine Agyaa Yobo
    AU  - Ransford Kyeremeh
    AU  - John Tetteh
    AU  - Richard Harry Asmah
    AU  - Patrick Ayeh-Kumi
    Y1  - 2014/05/20
    PY  - 2014
    N1  - https://doi.org/10.11648/j.ejpm.20140202.12
    DO  - 10.11648/j.ejpm.20140202.12
    T2  - European Journal of Preventive Medicine
    JF  - European Journal of Preventive Medicine
    JO  - European Journal of Preventive Medicine
    SP  - 25
    EP  - 28
    PB  - Science Publishing Group
    SN  - 2330-8230
    UR  - https://doi.org/10.11648/j.ejpm.20140202.12
    AB  - Blood donors are required to meet several criteria which are intended to ensure that safe blood is made available for transfusion as well as keeping the donor safe. Plasma glucose levels may be altered immediately after blood donation. However, since plasma glucose testing is not part of the screening tests, individuals who may have low or high plasma glucose levels are likely to be passed fit to donate. This may be detrimental to their health. The objective of the study was to measure the random plasma glucose (RPG) levels in blood donors before and after donation and determine whether there is any significant change in their levels. Samples were obtained from the Accra Area Blood Centre (AABC) at the Korle-Bu teaching Hospital. Two hundred (200) subjects were recruited who were healthy individuals between the ages of 18-52 years who had satisfied the donor criteria set by the AABC. Pre-and-post donation RPG level for each sample was determined using the VitaLab Junior Selectra Clinical Chemistry analyzer. Majority of the subjects were in the age-range of 21-30 years and there were more males than females. The mean RPG concentration before donation was 5.70±2.24 mmol/l and 9.07±6.48 mmol/l afterwards. 95% confidence interval was used and the difference was statistically significant (p<0.001). The findings indicate that the level of RPG is altered (mostly elevated) after blood donation. Knowing pre-donation glucose levels may therefore be important in keeping the donor safe.
    VL  - 2
    IS  - 2
    ER  - 

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Author Information
  • Department of Medical Laboratory Sciences, School of Allied Health Sciences, College of Health Sciences, University of Ghana, Korle-Bu, Accra, Ghana

  • The Accra Area Blood Centre, Korle-bu Teaching Hospital, Accra, Ghana

  • Department of Medical Laboratory Sciences, School of Allied Health Sciences, College of Health Sciences, University of Ghana, Korle-Bu, Accra, Ghana

  • The Accra Area Blood Centre, Korle-bu Teaching Hospital, Accra, Ghana

  • Department of Medical Laboratory Sciences, School of Allied Health Sciences, College of Health Sciences, University of Ghana, Korle-Bu, Accra, Ghana

  • Department of Medical Laboratory Sciences, School of Allied Health Sciences, College of Health Sciences, University of Ghana, Korle-Bu, Accra, Ghana

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