European Journal of Preventive Medicine

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Determination of Microalbuminuraia and Its Relation to HTN in Type 2 Diabetic Patients and General People

Received: 23 October 2019    Accepted: 12 November 2019    Published: 26 November 2019
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Abstract

Background: Microalbuminuria is a clinical marker of glomerular injury and identified as a risk of progressive renal damage, cardiovascular disease and morbidity. Hypertension (HTN) is a worldwide public health problem andcommonly coexists with Diabetes Mellitus (DM). Objective: The aim of the study was todetermine the prevalence of microalbuminuriain type 2diabetic patients and general people and the relationship between microalbuminuria withHTN and other clinical parametersin these twogroups of people. Methodology: A cross-sectional study was carried out using a pretested structured questionnaire amongrandomly selected107 participants aged from 35-70 years. Out of 107 participants 64 persons were type 2 diabetic patients and 43 were healthy individuals. Biochemical analysis of blood and urine samples was performed. Result: The prevalence of microalbuminuria was 17.2% in diabetic patients and 25.6% ingeneral people whereas the prevalence of HTN was 48.4% among diabetic patients and 51.6% in normal healthy persons. Regardless of the group considered, when microalbuminuria was analyzed according to the different clinical parameters, microalbuminuricpatients had significantly highersystolic (p=0.03) diastolic (p=0.02) blood pressure, urine creatinine (p=0.000), serum creatinine (p=0.012), urine albumin (p=0.019) and GFR (p=0.000). Microalbuminuria was found to be associated with HTN (odds ratio [OR] 3.5, 95% confidence interval [CI] 1.2-9.7). Conclusion: The study concluded thatmicroalbuminuria prevalence is high among general people and HTN has a significant relationship with microalbuminuria. These findings suggest early screening of microalbuminuria and the proper management of other clinical parameters to halt and prevent end stage renal disease and cardiovascular risk in future.

DOI 10.11648/j.ejpm.20190706.15
Published in European Journal of Preventive Medicine (Volume 7, Issue 6, December 2019)
Page(s) 117-122
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Microalbuminuria, Hypertension, Type 2 Diabetes Mellitus, General People

References
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Author Information
  • Department of Public Health and Informatics, Jahangirnagar University, Dhaka, Bangladesh

  • Department of Public Health and Informatics, Jahangirnagar University, Dhaka, Bangladesh

  • Department of Public Health and Informatics, Jahangirnagar University, Dhaka, Bangladesh

  • Department of Public Health and Informatics, Jahangirnagar University, Dhaka, Bangladesh

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  • APA Style

    Nowshin Monir, Zebunnesa Zeba, Sharmin Sultana, Ijajul Islam. (2019). Determination of Microalbuminuraia and Its Relation to HTN in Type 2 Diabetic Patients and General People. European Journal of Preventive Medicine, 7(6), 117-122. https://doi.org/10.11648/j.ejpm.20190706.15

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    ACS Style

    Nowshin Monir; Zebunnesa Zeba; Sharmin Sultana; Ijajul Islam. Determination of Microalbuminuraia and Its Relation to HTN in Type 2 Diabetic Patients and General People. Eur. J. Prev. Med. 2019, 7(6), 117-122. doi: 10.11648/j.ejpm.20190706.15

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    AMA Style

    Nowshin Monir, Zebunnesa Zeba, Sharmin Sultana, Ijajul Islam. Determination of Microalbuminuraia and Its Relation to HTN in Type 2 Diabetic Patients and General People. Eur J Prev Med. 2019;7(6):117-122. doi: 10.11648/j.ejpm.20190706.15

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  • @article{10.11648/j.ejpm.20190706.15,
      author = {Nowshin Monir and Zebunnesa Zeba and Sharmin Sultana and Ijajul Islam},
      title = {Determination of Microalbuminuraia and Its Relation to HTN in Type 2 Diabetic Patients and General People},
      journal = {European Journal of Preventive Medicine},
      volume = {7},
      number = {6},
      pages = {117-122},
      doi = {10.11648/j.ejpm.20190706.15},
      url = {https://doi.org/10.11648/j.ejpm.20190706.15},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ejpm.20190706.15},
      abstract = {Background: Microalbuminuria is a clinical marker of glomerular injury and identified as a risk of progressive renal damage, cardiovascular disease and morbidity. Hypertension (HTN) is a worldwide public health problem andcommonly coexists with Diabetes Mellitus (DM). Objective: The aim of the study was todetermine the prevalence of microalbuminuriain type 2diabetic patients and general people and the relationship between microalbuminuria withHTN and other clinical parametersin these twogroups of people. Methodology: A cross-sectional study was carried out using a pretested structured questionnaire amongrandomly selected107 participants aged from 35-70 years. Out of 107 participants 64 persons were type 2 diabetic patients and 43 were healthy individuals. Biochemical analysis of blood and urine samples was performed. Result: The prevalence of microalbuminuria was 17.2% in diabetic patients and 25.6% ingeneral people whereas the prevalence of HTN was 48.4% among diabetic patients and 51.6% in normal healthy persons. Regardless of the group considered, when microalbuminuria was analyzed according to the different clinical parameters, microalbuminuricpatients had significantly highersystolic (p=0.03) diastolic (p=0.02) blood pressure, urine creatinine (p=0.000), serum creatinine (p=0.012), urine albumin (p=0.019) and GFR (p=0.000). Microalbuminuria was found to be associated with HTN (odds ratio [OR] 3.5, 95% confidence interval [CI] 1.2-9.7). Conclusion: The study concluded thatmicroalbuminuria prevalence is high among general people and HTN has a significant relationship with microalbuminuria. These findings suggest early screening of microalbuminuria and the proper management of other clinical parameters to halt and prevent end stage renal disease and cardiovascular risk in future.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Determination of Microalbuminuraia and Its Relation to HTN in Type 2 Diabetic Patients and General People
    AU  - Nowshin Monir
    AU  - Zebunnesa Zeba
    AU  - Sharmin Sultana
    AU  - Ijajul Islam
    Y1  - 2019/11/26
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ejpm.20190706.15
    DO  - 10.11648/j.ejpm.20190706.15
    T2  - European Journal of Preventive Medicine
    JF  - European Journal of Preventive Medicine
    JO  - European Journal of Preventive Medicine
    SP  - 117
    EP  - 122
    PB  - Science Publishing Group
    SN  - 2330-8230
    UR  - https://doi.org/10.11648/j.ejpm.20190706.15
    AB  - Background: Microalbuminuria is a clinical marker of glomerular injury and identified as a risk of progressive renal damage, cardiovascular disease and morbidity. Hypertension (HTN) is a worldwide public health problem andcommonly coexists with Diabetes Mellitus (DM). Objective: The aim of the study was todetermine the prevalence of microalbuminuriain type 2diabetic patients and general people and the relationship between microalbuminuria withHTN and other clinical parametersin these twogroups of people. Methodology: A cross-sectional study was carried out using a pretested structured questionnaire amongrandomly selected107 participants aged from 35-70 years. Out of 107 participants 64 persons were type 2 diabetic patients and 43 were healthy individuals. Biochemical analysis of blood and urine samples was performed. Result: The prevalence of microalbuminuria was 17.2% in diabetic patients and 25.6% ingeneral people whereas the prevalence of HTN was 48.4% among diabetic patients and 51.6% in normal healthy persons. Regardless of the group considered, when microalbuminuria was analyzed according to the different clinical parameters, microalbuminuricpatients had significantly highersystolic (p=0.03) diastolic (p=0.02) blood pressure, urine creatinine (p=0.000), serum creatinine (p=0.012), urine albumin (p=0.019) and GFR (p=0.000). Microalbuminuria was found to be associated with HTN (odds ratio [OR] 3.5, 95% confidence interval [CI] 1.2-9.7). Conclusion: The study concluded thatmicroalbuminuria prevalence is high among general people and HTN has a significant relationship with microalbuminuria. These findings suggest early screening of microalbuminuria and the proper management of other clinical parameters to halt and prevent end stage renal disease and cardiovascular risk in future.
    VL  - 7
    IS  - 6
    ER  - 

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