Objective: Review the relationship between thiamine and schizophrenia. Methods: Information was obtained from MEDLINE. Results: Nutritional status has been related to the development of schizophrenia. Genetic studies have identified numerous factors that link thiamine to schizophrenia, including the renin angiotensin system, heme oxygenase-1, advanced glycation end products, alpha-antitrypsin, coenzyme Q10, glycogen synthetase kinase-3, and the transcription factor p53. Thiamine has also been implicated in schizophrenia via its effects on matrix metalloproteinases, the Wnt/β-catenin signaling pathway, the mitogen-activated protein kinase pathways, the reduced form of nicotinamide adenine dinucleotide phosphate, prostaglandins, cyclooxygenase-2, reactive oxidative stress, and nitric oxide synthase. Conclusions: These data suggest a role of thiamine in patients with schizophrenia. Therefore, additional investigation of thiamine in schizophrenic patients is required.
| Published in | American Journal of Psychiatry and Neuroscience (Volume 1, Issue 3) |
| DOI | 10.11648/j.ajpn.20130103.11 |
| Page(s) | 38-46 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Thiamine, Schizophrenia, Transketolase, Vitamin B1
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APA Style
Khanh vinh quốc Lương, Lan Thi Hoàng Nguyễn. (2013). The Role of Thiamine in Schizophrenia. American Journal of Psychiatry and Neuroscience, 1(3), 38-46. https://doi.org/10.11648/j.ajpn.20130103.11
ACS Style
Khanh vinh quốc Lương; Lan Thi Hoàng Nguyễn. The Role of Thiamine in Schizophrenia. Am. J. Psychiatry Neurosci. 2013, 1(3), 38-46. doi: 10.11648/j.ajpn.20130103.11
AMA Style
Khanh vinh quốc Lương, Lan Thi Hoàng Nguyễn. The Role of Thiamine in Schizophrenia. Am J Psychiatry Neurosci. 2013;1(3):38-46. doi: 10.11648/j.ajpn.20130103.11
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Download@article{10.11648/j.ajpn.20130103.11,
author = {Khanh vinh quốc Lương and Lan Thi Hoàng Nguyễn},
title = {The Role of Thiamine in Schizophrenia},
journal = {American Journal of Psychiatry and Neuroscience},
volume = {1},
number = {3},
pages = {38-46},
doi = {10.11648/j.ajpn.20130103.11},
url = {https://doi.org/10.11648/j.ajpn.20130103.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajpn.20130103.11},
abstract = {Objective: Review the relationship between thiamine and schizophrenia. Methods: Information was obtained from MEDLINE. Results: Nutritional status has been related to the development of schizophrenia. Genetic studies have identified numerous factors that link thiamine to schizophrenia, including the renin angiotensin system, heme oxygenase-1, advanced glycation end products, alpha-antitrypsin, coenzyme Q10, glycogen synthetase kinase-3, and the transcription factor p53. Thiamine has also been implicated in schizophrenia via its effects on matrix metalloproteinases, the Wnt/β-catenin signaling pathway, the mitogen-activated protein kinase pathways, the reduced form of nicotinamide adenine dinucleotide phosphate, prostaglandins, cyclooxygenase-2, reactive oxidative stress, and nitric oxide synthase. Conclusions: These data suggest a role of thiamine in patients with schizophrenia. Therefore, additional investigation of thiamine in schizophrenic patients is required.},
year = {2013}
}
TY - JOUR T1 - The Role of Thiamine in Schizophrenia AU - Khanh vinh quốc Lương AU - Lan Thi Hoàng Nguyễn Y1 - 2013/11/30 PY - 2013 N1 - https://doi.org/10.11648/j.ajpn.20130103.11 DO - 10.11648/j.ajpn.20130103.11 T2 - American Journal of Psychiatry and Neuroscience JF - American Journal of Psychiatry and Neuroscience JO - American Journal of Psychiatry and Neuroscience SP - 38 EP - 46 PB - Science Publishing Group SN - 2330-426X UR - https://doi.org/10.11648/j.ajpn.20130103.11 AB - Objective: Review the relationship between thiamine and schizophrenia. Methods: Information was obtained from MEDLINE. Results: Nutritional status has been related to the development of schizophrenia. Genetic studies have identified numerous factors that link thiamine to schizophrenia, including the renin angiotensin system, heme oxygenase-1, advanced glycation end products, alpha-antitrypsin, coenzyme Q10, glycogen synthetase kinase-3, and the transcription factor p53. Thiamine has also been implicated in schizophrenia via its effects on matrix metalloproteinases, the Wnt/β-catenin signaling pathway, the mitogen-activated protein kinase pathways, the reduced form of nicotinamide adenine dinucleotide phosphate, prostaglandins, cyclooxygenase-2, reactive oxidative stress, and nitric oxide synthase. Conclusions: These data suggest a role of thiamine in patients with schizophrenia. Therefore, additional investigation of thiamine in schizophrenic patients is required. VL - 1 IS - 3 ER -
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