American Journal of Psychiatry and Neuroscience

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Intracranial Aspergillosis Mimicking a Middle Cranial Fossa Tumor Involving the Cavernous Sinus in an Immunocompetent Patient: Case Report and Literature Review

Received: 01 September 2014    Accepted: 11 September 2014    Published: 20 September 2014
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Abstract

Intracranial aspergillosis is rare in immunocompetent patients. Extension to the cranial base via the sphenoid sinus is exceptional. Authors report a case of middle cranial fossa aspergillosis involving the cavernous sinus and mimicking an extra-axial tumor in an immunocompetent 65 year-old male. The patient had been suffering from left trigeminal neuralgia and a horizontal diplopia since 4 months. Physical examination featured a left complete ophtalmoplegia and an hyperesthesia of the left maxillary nerve. Radiological examination showed a left temporal extra-axial temporal expanding intracranial lesion, involving the left cavernous sinus with extension to the sphenoidal sinus. A large tumor resection was performed through a left fronto-temporal craniotomy with no postoperative complications. Pathologic examination and specimen culture concluted to an Aspergillus fumigatus. Authors discuss the clinical, radiological features and management of such lesion through a literature review.

DOI 10.11648/j.ajpn.20140204.12
Published in American Journal of Psychiatry and Neuroscience (Volume 2, Issue 4, July 2014)
Page(s) 56-59
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Aspergillosis, Middle Cranial Fossa, Cavernous Sinus, Sphenoid Sinus

References
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[2] Alapatt JP, Kutty RK, Gopi PP, Challissery J. Middle and posterior fossa aspergilloma. Surg Neurol 2006;66(1):75-79.
[3] Browning AC, Sim KT, Timms JM, Vernon SA, McCanachie NS, Allibone R, et al. Successful treatment of invasive cavernous sinus aspergillosis with oral itraconazole monotherapy. J Neuro-Ophtalmol 2006;26(2):103-106.
[4] Chandra S, Goyal M, Mishra NK, Gaikward SB. Invasive aspergillosis presenting as a cavernous sinus mass in immunocompetent individuals; report of 3 cases. Neuroradiology 2000;42:108-111.
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[13] Genzen JR, Kennedy B. Central nervous system Aspergillus infection after epidural analgesia: diagnosis, therapeutic challenges and literature review. Diag Microbiol Inf dis 2009;65:312-318.
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[18] Petrick M, Honegger J, Daschner F, Feuerhake F, Zentner J. fungal granuloma of the sphenoid sinus and clivus in a patient presenting with cranial nerve III paresis: case report and review of the litterature. Neurosurgery 2003;52:955-959.
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Author Information
  • Department of Neurosurgery, Burns and Trauma center, Ben Arous, Tunisia

  • Department of Neurosurgery, National Institute of Neurology “Mongi Ben Hmida”, Tunis, Tunisia

  • Department of Neurosurgery, National Institute of Neurology “Mongi Ben Hmida”, Tunis, Tunisia

  • Department of Neurosurgery, Burns and Trauma center, Ben Arous, Tunisia

  • Department of Neurosurgery, National Institute of Neurology “Mongi Ben Hmida”, Tunis, Tunisia

  • Department of Neurosurgery, Burns and Trauma center, Ben Arous, Tunisia

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    Mohamed Badri, Bouali Sofiene, Boubaker Adnene, Bahri Kamel, Jemel Hafedh, et al. (2014). Intracranial Aspergillosis Mimicking a Middle Cranial Fossa Tumor Involving the Cavernous Sinus in an Immunocompetent Patient: Case Report and Literature Review. American Journal of Psychiatry and Neuroscience, 2(4), 56-59. https://doi.org/10.11648/j.ajpn.20140204.12

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    ACS Style

    Mohamed Badri; Bouali Sofiene; Boubaker Adnene; Bahri Kamel; Jemel Hafedh, et al. Intracranial Aspergillosis Mimicking a Middle Cranial Fossa Tumor Involving the Cavernous Sinus in an Immunocompetent Patient: Case Report and Literature Review. Am. J. Psychiatry Neurosci. 2014, 2(4), 56-59. doi: 10.11648/j.ajpn.20140204.12

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    AMA Style

    Mohamed Badri, Bouali Sofiene, Boubaker Adnene, Bahri Kamel, Jemel Hafedh, et al. Intracranial Aspergillosis Mimicking a Middle Cranial Fossa Tumor Involving the Cavernous Sinus in an Immunocompetent Patient: Case Report and Literature Review. Am J Psychiatry Neurosci. 2014;2(4):56-59. doi: 10.11648/j.ajpn.20140204.12

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  • @article{10.11648/j.ajpn.20140204.12,
      author = {Mohamed Badri and Bouali Sofiene and Boubaker Adnene and Bahri Kamel and Jemel Hafedh and Zammel Ihsen},
      title = {Intracranial Aspergillosis Mimicking a Middle Cranial Fossa Tumor Involving the Cavernous Sinus in an Immunocompetent Patient: Case Report and Literature Review},
      journal = {American Journal of Psychiatry and Neuroscience},
      volume = {2},
      number = {4},
      pages = {56-59},
      doi = {10.11648/j.ajpn.20140204.12},
      url = {https://doi.org/10.11648/j.ajpn.20140204.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajpn.20140204.12},
      abstract = {Intracranial aspergillosis is rare in immunocompetent patients. Extension to the cranial base via the sphenoid sinus is exceptional. Authors report a case of middle cranial fossa aspergillosis involving the cavernous sinus and mimicking an extra-axial tumor in an immunocompetent 65 year-old male. The patient had been suffering from left trigeminal neuralgia and a horizontal diplopia since 4 months. Physical examination featured a left complete ophtalmoplegia and an hyperesthesia of the left maxillary nerve. Radiological examination showed a left temporal extra-axial temporal expanding intracranial lesion, involving the left cavernous sinus with extension to the sphenoidal sinus. A large tumor resection was performed through a left fronto-temporal craniotomy with no postoperative complications. Pathologic examination and specimen culture concluted to an Aspergillus fumigatus. Authors discuss the clinical, radiological features and management of such lesion through a literature review.},
     year = {2014}
    }
    

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    AU  - Mohamed Badri
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