The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion

Bekhzod Abdullaev; Elvina Giyazitdinova; Yulduz Musaeva

doi:doi:10.11648/j.ajpn.20170505.12

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The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion

Bekhzod Abdullaev, Elvina Giyazitdinova, Yulduz Musaeva

Published in American Journal of Psychiatry and Neuroscience (Volume 5, Issue 5)

Received: 9 July 2017 Accepted: 24 August 2017 Published: 21 September 2017

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Abstract

The most susceptible to vascular dementia persons with lesions of small cerebral vessels. This variant of the pathology is characterized by subacute course and pathologic basis is diffuse changes in the white matter of the cerebral hemispheres and lacunar infarctions, in most cases - multiple. That is why the appearance of lacunar infarcts associated with step-progression of the disease. However, not in all cases, there is a significant cognitive defect even in a lacunary condition. The aim of the study was to identify cognitive impairment in patients with lacunar stroke, depending on hemispheric lateralization of the lesion. We observed and surveyed 70 patients (mean age 60.2 + 6.3) suffered the lacunar stroke with hemispheric lateralization of the lesion. In this work, we used the Mini-Mental State Examination (MMSE) and Montreal scale assessment of cognitive functions (MoCA), the Saint Louis University Mental Status Examination (SLUMS), which have been developed as a tool to identify and assess the severity of cognitive functions in general practice. Comparative analysis of cognitive impairment on the stage of the disease in the control group showed that in general, patients suffered lacunar stroke level of violations was significantly higher than the control group (p≤0.01). Cognitive function in right lacunar stroke corresponded moderate cognitive impairment and the restoration of the neurological defect in the dynamics were less expressed and are not complete. Cognitive impairment in the left hemisphere lacunar stroke had a mild degree of cognitive impairment and restoration of disturbed functions is progressing at a faster pace, about what speak reliable indicators of the late recovery period (p≤0.05). The differences in cognitive disorders at different focus lateralization underlie the clinical features and determine the nature and pace of the recovery of lost functions. Mild cognitive impairment in the left-hand lacunar stroke is a favorable prognostic factor in terms of the recovery of lost functions.

Published in	American Journal of Psychiatry and Neuroscience (Volume 5, Issue 5)
DOI	10.11648/j.ajpn.20170505.12
Page(s)	56-59
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Lacunar Stroke, Vascular Dementia, Cognitive Impairment

References

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[8]	Clavier I., Hommel M., Besson G. Long-term prognosis of symptomatic lacunar infarcts. Ahospital-basedstudy. Stroke. 2014.
[9]	Chertkow H. Diagnosis and treatment of dementia: introduction. Introducing a series based on the third Canadian consensus conference on the diagnosis and treatment of dementia // CMAJ: Canad. Med. Assoc. J. 2015. - Vol. 178, № 10 -P. 316-321.
[10]	Debette S., Bombois S., Bruandet A. et al. Subcortical hyperintensities are associated with cognitive decline in patients with mild cognitive impairment // Stroke. 2007. № 38. P. 2595-2597.
[11]	Chui H. Subcortical ischemic vascular dementia (SIVD) // Neurol. Clin. 2007. - Vol. 25, №. 3. - P. 717-717.
[12]	Giovannetti, T. Personal Interview. 16 October 2009.
[13]	Tatemichi TK, Desmond DW, Stern Y, Paik M, Sano M, Bagiella E. Cognitive impairment after stroke: frequency, patterns, and relationship to functional abilities. J Neurol Neurosurg Psychiatry 1994; 57: 202-7.
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[17]	Meier MJ, Ettinger MC, ARthur L. Recovery of neuropsyhological functioning after cerebrovascular infarction. Neuropsychology and cognition. NATO Advanced Study Series 1982; 552-64.

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Bekhzod Abdullaev, Elvina Giyazitdinova, Yulduz Musaeva. (2017). The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion. American Journal of Psychiatry and Neuroscience, 5(5), 56-59. https://doi.org/10.11648/j.ajpn.20170505.12

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ACS Style

Bekhzod Abdullaev; Elvina Giyazitdinova; Yulduz Musaeva. The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion. Am. J. Psychiatry Neurosci. 2017, 5(5), 56-59. doi: 10.11648/j.ajpn.20170505.12

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AMA Style

Bekhzod Abdullaev, Elvina Giyazitdinova, Yulduz Musaeva. The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion. Am J Psychiatry Neurosci. 2017;5(5):56-59. doi: 10.11648/j.ajpn.20170505.12

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@article{10.11648/j.ajpn.20170505.12,
  author = {Bekhzod Abdullaev and Elvina Giyazitdinova and Yulduz Musaeva},
  title = {The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion},
  journal = {American Journal of Psychiatry and Neuroscience},
  volume = {5},
  number = {5},
  pages = {56-59},
  doi = {10.11648/j.ajpn.20170505.12},
  url = {https://doi.org/10.11648/j.ajpn.20170505.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajpn.20170505.12},
  abstract = {The most susceptible to vascular dementia persons with lesions of small cerebral vessels. This variant of the pathology is characterized by subacute course and pathologic basis is diffuse changes in the white matter of the cerebral hemispheres and lacunar infarctions, in most cases - multiple. That is why the appearance of lacunar infarcts associated with step-progression of the disease. However, not in all cases, there is a significant cognitive defect even in a lacunary condition. The aim of the study was to identify cognitive impairment in patients with lacunar stroke, depending on hemispheric lateralization of the lesion. We observed and surveyed 70 patients (mean age 60.2 + 6.3) suffered the lacunar stroke with hemispheric lateralization of the lesion. In this work, we used the Mini-Mental State Examination (MMSE) and Montreal scale assessment of cognitive functions (MoCA), the Saint Louis University Mental Status Examination (SLUMS), which have been developed as a tool to identify and assess the severity of cognitive functions in general practice. Comparative analysis of cognitive impairment on the stage of the disease in the control group showed that in general, patients suffered lacunar stroke level of violations was significantly higher than the control group (p≤0.01). Cognitive function in right lacunar stroke corresponded moderate cognitive impairment and the restoration of the neurological defect in the dynamics were less expressed and are not complete. Cognitive impairment in the left hemisphere lacunar stroke had a mild degree of cognitive impairment and restoration of disturbed functions is progressing at a faster pace, about what speak reliable indicators of the late recovery period (p≤0.05). The differences in cognitive disorders at different focus lateralization underlie the clinical features and determine the nature and pace of the recovery of lost functions. Mild cognitive impairment in the left-hand lacunar stroke is a favorable prognostic factor in terms of the recovery of lost functions.},
 year = {2017}
}

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TY  - JOUR
T1  - The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion
AU  - Bekhzod Abdullaev
AU  - Elvina Giyazitdinova
AU  - Yulduz Musaeva
Y1  - 2017/09/21
PY  - 2017
N1  - https://doi.org/10.11648/j.ajpn.20170505.12
DO  - 10.11648/j.ajpn.20170505.12
T2  - American Journal of Psychiatry and Neuroscience
JF  - American Journal of Psychiatry and Neuroscience
JO  - American Journal of Psychiatry and Neuroscience
SP  - 56
EP  - 59
PB  - Science Publishing Group
SN  - 2330-426X
UR  - https://doi.org/10.11648/j.ajpn.20170505.12
AB  - The most susceptible to vascular dementia persons with lesions of small cerebral vessels. This variant of the pathology is characterized by subacute course and pathologic basis is diffuse changes in the white matter of the cerebral hemispheres and lacunar infarctions, in most cases - multiple. That is why the appearance of lacunar infarcts associated with step-progression of the disease. However, not in all cases, there is a significant cognitive defect even in a lacunary condition. The aim of the study was to identify cognitive impairment in patients with lacunar stroke, depending on hemispheric lateralization of the lesion. We observed and surveyed 70 patients (mean age 60.2 + 6.3) suffered the lacunar stroke with hemispheric lateralization of the lesion. In this work, we used the Mini-Mental State Examination (MMSE) and Montreal scale assessment of cognitive functions (MoCA), the Saint Louis University Mental Status Examination (SLUMS), which have been developed as a tool to identify and assess the severity of cognitive functions in general practice. Comparative analysis of cognitive impairment on the stage of the disease in the control group showed that in general, patients suffered lacunar stroke level of violations was significantly higher than the control group (p≤0.01). Cognitive function in right lacunar stroke corresponded moderate cognitive impairment and the restoration of the neurological defect in the dynamics were less expressed and are not complete. Cognitive impairment in the left hemisphere lacunar stroke had a mild degree of cognitive impairment and restoration of disturbed functions is progressing at a faster pace, about what speak reliable indicators of the late recovery period (p≤0.05). The differences in cognitive disorders at different focus lateralization underlie the clinical features and determine the nature and pace of the recovery of lost functions. Mild cognitive impairment in the left-hand lacunar stroke is a favorable prognostic factor in terms of the recovery of lost functions.
VL  - 5
IS  - 5
ER  -

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Author Information

Bekhzod Abdullaev

Department of Neurology, Tashkent Medical Academy, Tashkent, Uzbekistan
Elvina Giyazitdinova

Department of Neurology, Tashkent Medical Academy, Tashkent, Uzbekistan
Yulduz Musaeva

Department of Neurology, Tashkent Medical Academy, Tashkent, Uzbekistan

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APA Style

Bekhzod Abdullaev, Elvina Giyazitdinova, Yulduz Musaeva. (2017). The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion. American Journal of Psychiatry and Neuroscience, 5(5), 56-59. https://doi.org/10.11648/j.ajpn.20170505.12

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ACS Style

Bekhzod Abdullaev; Elvina Giyazitdinova; Yulduz Musaeva. The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion. Am. J. Psychiatry Neurosci. 2017, 5(5), 56-59. doi: 10.11648/j.ajpn.20170505.12

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AMA Style

Bekhzod Abdullaev, Elvina Giyazitdinova, Yulduz Musaeva. The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion. Am J Psychiatry Neurosci. 2017;5(5):56-59. doi: 10.11648/j.ajpn.20170505.12

Copy | Download

@article{10.11648/j.ajpn.20170505.12,
  author = {Bekhzod Abdullaev and Elvina Giyazitdinova and Yulduz Musaeva},
  title = {The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion},
  journal = {American Journal of Psychiatry and Neuroscience},
  volume = {5},
  number = {5},
  pages = {56-59},
  doi = {10.11648/j.ajpn.20170505.12},
  url = {https://doi.org/10.11648/j.ajpn.20170505.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajpn.20170505.12},
  abstract = {The most susceptible to vascular dementia persons with lesions of small cerebral vessels. This variant of the pathology is characterized by subacute course and pathologic basis is diffuse changes in the white matter of the cerebral hemispheres and lacunar infarctions, in most cases - multiple. That is why the appearance of lacunar infarcts associated with step-progression of the disease. However, not in all cases, there is a significant cognitive defect even in a lacunary condition. The aim of the study was to identify cognitive impairment in patients with lacunar stroke, depending on hemispheric lateralization of the lesion. We observed and surveyed 70 patients (mean age 60.2 + 6.3) suffered the lacunar stroke with hemispheric lateralization of the lesion. In this work, we used the Mini-Mental State Examination (MMSE) and Montreal scale assessment of cognitive functions (MoCA), the Saint Louis University Mental Status Examination (SLUMS), which have been developed as a tool to identify and assess the severity of cognitive functions in general practice. Comparative analysis of cognitive impairment on the stage of the disease in the control group showed that in general, patients suffered lacunar stroke level of violations was significantly higher than the control group (p≤0.01). Cognitive function in right lacunar stroke corresponded moderate cognitive impairment and the restoration of the neurological defect in the dynamics were less expressed and are not complete. Cognitive impairment in the left hemisphere lacunar stroke had a mild degree of cognitive impairment and restoration of disturbed functions is progressing at a faster pace, about what speak reliable indicators of the late recovery period (p≤0.05). The differences in cognitive disorders at different focus lateralization underlie the clinical features and determine the nature and pace of the recovery of lost functions. Mild cognitive impairment in the left-hand lacunar stroke is a favorable prognostic factor in terms of the recovery of lost functions.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - The Degree of Cognitive Impairment in Patients with Lacunar Stroke Depending on the Hemispheric Lateralization of the Lesion
AU  - Bekhzod Abdullaev
AU  - Elvina Giyazitdinova
AU  - Yulduz Musaeva
Y1  - 2017/09/21
PY  - 2017
N1  - https://doi.org/10.11648/j.ajpn.20170505.12
DO  - 10.11648/j.ajpn.20170505.12
T2  - American Journal of Psychiatry and Neuroscience
JF  - American Journal of Psychiatry and Neuroscience
JO  - American Journal of Psychiatry and Neuroscience
SP  - 56
EP  - 59
PB  - Science Publishing Group
SN  - 2330-426X
UR  - https://doi.org/10.11648/j.ajpn.20170505.12
AB  - The most susceptible to vascular dementia persons with lesions of small cerebral vessels. This variant of the pathology is characterized by subacute course and pathologic basis is diffuse changes in the white matter of the cerebral hemispheres and lacunar infarctions, in most cases - multiple. That is why the appearance of lacunar infarcts associated with step-progression of the disease. However, not in all cases, there is a significant cognitive defect even in a lacunary condition. The aim of the study was to identify cognitive impairment in patients with lacunar stroke, depending on hemispheric lateralization of the lesion. We observed and surveyed 70 patients (mean age 60.2 + 6.3) suffered the lacunar stroke with hemispheric lateralization of the lesion. In this work, we used the Mini-Mental State Examination (MMSE) and Montreal scale assessment of cognitive functions (MoCA), the Saint Louis University Mental Status Examination (SLUMS), which have been developed as a tool to identify and assess the severity of cognitive functions in general practice. Comparative analysis of cognitive impairment on the stage of the disease in the control group showed that in general, patients suffered lacunar stroke level of violations was significantly higher than the control group (p≤0.01). Cognitive function in right lacunar stroke corresponded moderate cognitive impairment and the restoration of the neurological defect in the dynamics were less expressed and are not complete. Cognitive impairment in the left hemisphere lacunar stroke had a mild degree of cognitive impairment and restoration of disturbed functions is progressing at a faster pace, about what speak reliable indicators of the late recovery period (p≤0.05). The differences in cognitive disorders at different focus lateralization underlie the clinical features and determine the nature and pace of the recovery of lost functions. Mild cognitive impairment in the left-hand lacunar stroke is a favorable prognostic factor in terms of the recovery of lost functions.
VL  - 5
IS  - 5
ER  -

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