American Journal of Biomedical and Life Sciences
Volume 2, Issue 1, February 2014, Pages: 28-33
Received: Feb. 10, 2014;
Published: Mar. 20, 2014
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Ajuru, Gospel, Department of Anatomical Pathology, Faculty of Basic Medical Science, University of Port Harcourt, Choba, Nigeria
Okolonkwo, Benjamin, Department of Medical Laboratory Science, Faculty of Science, Rivers State University of Science and Technology, Port Harcourt, Nigeria
Okeke, Chukwubike, Department of Prosthesis and Orthopedic Technology, Federal University of Technology, Owerri, Nigeria
Studies on the effect of non-hypertensive and hypertensive type 2 diabetes on lipid profile was performed to determine whether these biochemical parameters were affected in individuals associated with these disease conditions. A total of one hundred and thirty-three (133) individuals were used for these studies. Of these thirty-five (35) were established hypertensive diabetics and thirty (30) are established non-hypertensive diabetics. The established hypertensive non-diabetics were thirty-three (33) while thirty-five (35) were normal healthy individuals. The results showed that there was no significant differences (P>0.05) in the mean concentrations of cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol and glucose between hypertensive diabetics and non-hypertensive diabetics studied. The study also showed that there were no significance differences (P>0.05) in the mean levels of all the parameters measured between hypertensive diabetics and hypertensive non-diabetics subjects studied, except for serum glucose that significantly higher (P<0.05) in hypertensive diabetics. It was observed that mean concentrations of cholesterol, triglycerides, LDC-cholesterol, as well as systolic blood pressure were significantly higher (P<0.05) in hypertensive diabetics compared with normal healthy individuals. The results also show that the mean HDL-cholesterol level was significantly lower (P>0.05) in hypertensive diabetics compared with normal healthy individuals. It was also observed that the concentrations of cholesterol, triglycerides, LDL-cholesterol systolic and diastolic blood pressure were significantly higher (P>0.05) in hypertensive non diabetics individuals compared with normal healthy individuals studied. However, the glucose and pulse rate mean levels showed no significant difference (P>0.05) between hypertensive non-diabetics and normal healthy individuals.
Studies on Lipid Profile Levels in Hypertensive and Type 2 Diabetes Mellitus, American Journal of Biomedical and Life Sciences.
Vol. 2, No. 1,
2014, pp. 28-33.
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