Stability Analysis of Formulated Emulsion Containing Black Cumin (Nigella sativa) Oil
American Journal of Biomedical and Life Sciences
Volume 4, Issue 3, June 2016, Pages: 49-53
Received: May 6, 2016; Accepted: May 16, 2016; Published: May 28, 2016
Views 4093      Downloads 239
Authors
Shanita Zaman Smrity, Department of Pharmacy, Jahangirnagar University, Savar, Dhaka, Bangladesh
A. H. M. Saifuddin, Department of Pharmacy, Jahangirnagar University, Savar, Dhaka, Bangladesh
Sakina Sultana, Department of Pharmacy, Jahangirnagar University, Savar, Dhaka, Bangladesh
Article Tools
Follow on us
Abstract
In this present study emulsions were prepared by using black cumin oil. Dry gum method was followed to prepare emulsions formula A & B. Stability tests including organoleptic property evaluation, pH test, accelerated stability studies, water-drop test and peroxide value were determined. In case of organoleptic property evaluation emulsions showed insignificant changes and there were no variation in pH in both preparations up to 3 months. Emulsions were also undergone to different temperature effects and centrifugation at 4000 rpm, but lost the homogenous structure and separated into two phases under the effect of light and centrifugation. The study showed better results for emulsion B comparing with emulsion A. Thus our results showed that emulsion formulation B can be a good semi-solid preparation in Pharmaceutical field and food industry.
Keywords
Black Cumin Oil, Emulsions, Dry Gum Method, Stability Tests, Better Results, Pharmaceutical Field
To cite this article
Shanita Zaman Smrity, A. H. M. Saifuddin, Sakina Sultana, Stability Analysis of Formulated Emulsion Containing Black Cumin (Nigella sativa) Oil, American Journal of Biomedical and Life Sciences. Vol. 4, No. 3, 2016, pp. 49-53. doi: 10.11648/j.ajbls.20160403.15
Copyright
Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
[1]
Carter, S. J. Cooper & Gunn’s Dispensing for Pharmaceutical Students. 12th edition, CBS Publishers & Distributors, India; 1987. pp-120.
[2]
Shargel, L., Mutnick, A. H., Souney. P. F, Swason, L. N. (2007). Comprehensive Pharmacy Review. 6th edition. Wolters Kluwer Health (India) Pvt, LTD.
[3]
Lachman, L., Lieberman, H. A., Kanig, J. L. (1987). The Theory and Practice of Industrial Pharmacy. 4th edition, Lea and Febriger, Philadelphia, U.S.A. pp- 266-267, 529.
[4]
Kentish, S., Wooster, T. J., Ashokkumar, M., Balachandran, S., Mawson, R., Simons, L. (2008). The Use of Ultrasonics for nanoemulsion preparation. Innovative food science and emerging technologies. 9(2): 170-175.
[5]
Mason, T. G., Wilking, J. N., Meleson, K., Chang, C. B., Graves, S. M. (2006). Nanoemulsions: formation, structure, and physical properties. Journal of Physics: Condensed Matter. 18(41): 635-666
[6]
Sharma, N. K., Ahirwar, D., Jhade, D. and Gupta. S. (2009). Medicinal and pharmacological potential of Nigella sativa: A review. Ethnobotanical review. 13: 946-55.
[7]
Allen Jr, L. V., Popovich, N. G., Ansel, H. C. (eds.). (2005). Ansel’s pharmaceutical dosage form and drug delivery systems. 8th edition. Lippincott Williams and Wilkins, Philadelphia, USA. pp- 409, 414.
[8]
Aulton, M. E. (1990). Pharmaceutical practice. 1st Edition. Longman Singapore Publishers Pte Ltd. pp- 115.
[9]
Bolton, S., Bol, C. (2005). Pharmaceutical Statistics: Practical and Clinical Applications. 4th edition. Marcel Dekker, Inc. New York. pp- 468.
[10]
Smaoui, S., Hlima, H. B., Jarraya, R., Kamoun, N. G., Ellouze, R., and Damak, M. (2012). Cosmetic emulsion from virgin olive oil: Formulation and bio-physical evaluation. African Journal of Biotechnology. 11(40): 9664-9671.
[11]
Libermann, H. A., Reiger, M, M. and Banker, G.S. (eds). (1998). Pharmaceutical dosage forms. Dispersed system. Volume I. Marcel Dekker Inc. Newyork and Basel. pp: 234.
[12]
Becher, P. (1965). Emulsion theory and practice. 2nd edition. Reinhold, New York.
[13]
Lubrizol standard test procedure (2007). Lubrizol Advanced Materials, Inc. is a wholly owned subsidiary of The Lubrizol Corporation. Available from: www.personalcare.noveon.com
ADDRESS
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
U.S.A.
Tel: (001)347-983-5186