Assessment of Albumin Status in Hypertensive Patients with or Without Cataract in Eyes’ Foundation Hospital, Itamogiri, Ogun State, Nigeria
American Journal of Biomedical and Life Sciences
Volume 5, Issue 4, August 2017, Pages: 73-77
Received: Jun. 12, 2016;
Accepted: Sep. 19, 2016;
Published: Jul. 20, 2017
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Oladunjoye Z. A., Department of Medical Laboratory Techniques, Ogun State College of Health Technology, Ilese- Ijebu, Nigeria
Quadri J. A., Department of Nutrition and Dietetics, Ogun State College of Health Technology, Ilese - Ijebu, Nigeria
Ojure M. A., Department of Nutrition and Dietetics, Ogun State College of Health Technology, Ilese - Ijebu, Nigeria
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This research work assessed albumin concentration level in hypertensive patients with or without cataract at Eyes’ Foundation Hospital at Itamogiri, Ijebu – Mushin in ijebu-East Local Government Area and General Hospital Ijebu-Ode both in Ogun State, Nigeria. Simple random sampling was used to select the 150 samples from the study area. Fifty (50) healthy staffs and individuals who volunteered to help with the research were used as control group, while group A (test) comprises of fifty (50) hypertensive patients without history of cataract and group B (test) comprises of fifty (50) hypertensive patients with history of cataract. Blood samples were taken under the same conditions in all individuals and analysed for albumin level using spectrophotometer. The findings showed that there was no significant difference in albumin level between the control group (Mean ± SD = 48.12 ± 8.20 g/L) as compared with test group A (Mean ± SD = 49.19 ± 10.19 g/L) but in comparing albumin level in control group and test group B, the findings showed that there was significant reduction in albumin concentration of test group B with Mean ± SD = 44.35 ± 11.99 g/L indicating hypertension (with cataract) had significantly decreased levels of plasma albumin when compared to non-cataract hypertensive patients. This shows that cataract could directly influence increase in serum albumin concentration of hypertensive patients. Salt restricted diet should be advised in such patients after evaluating serum electrolyte level which may delay maturation and progression of Cataract.
Albumin, Cataract, Hypertension, Spectrophotometer
To cite this article
Oladunjoye Z. A.,
Quadri J. A.,
Ojure M. A.,
Assessment of Albumin Status in Hypertensive Patients with or Without Cataract in Eyes’ Foundation Hospital, Itamogiri, Ogun State, Nigeria, American Journal of Biomedical and Life Sciences.
Vol. 5, No. 4,
2017, pp. 73-77.
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Resnikoff S, Pascolini D, Etya'ale D, Kocur I, Pararajasegaram R, Pokharel GP, (2004); Global data on visual impairment in the year 2002. Bull World Health Organ; 82: 844-51.
Kyari F, Gudlavalleti M. V, Sivsubramaniam S, Gilbert C. E, Abdull M. M, Entekume G, Foster A. (2009); Prevalence of blindness and visual impairment in Nigeria: the National Blindness and Visual impairment study. Invest ophthalmol Vis Sci.; 50 (5): 2033-2039.
Bruce D. W, Gray C. S, (1991); Beyond the cataract: visual and functional disability in elderly people. Age Ageing; 20: 389-391.
Mac Carty C. A, Nanjan M. B, Taylor H. R. (2001); Vision impairment predicts 5 year mortality. Br J Ophthalmol.; 85: 322 – 326.
Schafer F. Q, Buettner G. R (2001); Redox environment of the cell as viewed through the redox state of the glutathione disulfide/ glutathione couple. Free Radic Biol Med, 30 (11): 1191 – 1212.
Beaulieu C, Rufiange M, Dumont M, Lachapelle P. (2009); Modulation of ERG retinal sensitivity parameters with light environment and photoperiod Documentiaophthamologica. 118: 89-99.
Bautista L. E, Vera L. M, Arenas I. A, Gamarra G. (2004); Independent association between inflammatory markers (C-creative protein, interleukin-6, and TNF-alpha) and essential hypertension. J Hum Hypertens; 19: 149-154.
Lee S, Colditz G. A, Berkman L. F, Kawachi I. (2004); Prospective study of job insecurity and coronary heart disease in US women. Annals of Epidemilogy. 14: 24-30.
Kayode S. Adedapo, Saudat T. Kareem, Charles O. Bekibele and Nnenna L. Nwobi (2012) Increased oxidative stress and non-enzymatic antioxidant levels in senile cataract. Department of Chemical Pathology, University College Hospital, Ibadan, Nigeria.
Sabanayagam C, Anoop S. (2011); Serum calcium levels and Hypertension Among US Adults; J Clinical Hypertension; 13: 716-721.
Richter G. M, Torres M, Choudhury F, Azen S. P, Varma R (2013); Risk factors for cortical, nuclear, posterior subcapsular, and mixed lens opacities: the Los Angeles Latino Eye Study. Ophthalmology 119: 547-554.
Screenivas V, Prabhakar A, Badrinath S. S, Fernandes T, Roy I. S (1999); A rural population based case-control study of senile cataract in India. J Epidemiol 9: 327-326.
Mukesh B. N, Le A, Dimitrov P. N, Ahmed S, Taylor H. R (2006); Development of cataract and associated risk factors. Arch Ophthalmol 124: 79-85.
Munoz R. F, Mrazek P. J and Haggerty R. J (1996); Institute of Medicine report on prevention of mental disorders: Summary and Commentary. American Psychologist 51: 1116-1122.
Bollinger K. E, Langston R. H (2008); What can patient expect from cataract sugery? Cleveland Clinic; Journal of medicine, 75 (3), 193-200.