Mansonella perstans and Plasmodium falciparum Co-infection in the Akonolinga Health District, Centre Region, Cameroon
American Journal of Biomedical and Life Sciences
Volume 7, Issue 1, February 2019, Pages: 16-21
Received: Feb. 25, 2019; Accepted: Mar. 28, 2019; Published: Apr. 13, 2019
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Authors
Leopold Gustave Lehman, Faculty of Sciences, University of Douala, Douala, Cameroon
Martin Gael Oyono, Faculty of Sciences, University of Yaoundé I, Yaoundé, Cameroon
Samuel Fosso, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon
Charles Félix Bilong Bilong, Faculty of Sciences, University of Yaoundé I, Yaoundé, Cameroon
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Abstract
Mansonella perstans and Plasmodium falciparum are among the most common human parasites in Sub-Saharan Africa. They pass through the bloodstream during their life in human host. This study aimed at determining the prevalence, determinants of co-infection with M. perstans and P. falciparum and their possible interaction mechanism. A cross-sectional study was conducted in the Akonolinga Health District among pupils. Each of them was screened for the presence of peripheral blood parasites stages using Giemsa-stained thick and thin blood films. Socio-demographic information was documented using a questionnaire forms. A total of 416 pupils aged 4-15 years (average: 9.17 ± 0.27) were recruited. The overall prevalence was 4.32% and 37.26% for M. perstans and P. falciparum respectively, and prevalence of co-infection was 1.92%. Mean parasite density was 508.7±310.3 (min: 430 - max: 1300) µF/ml for M. perstans and 5240.38±2037.42 (min: 857 – max: 10400) T/μl for P. falciparum. Risks of single infections (aOR = 0.46, P = 0.0264 for M. perstans and aOR = 0.64, P = 0.0432 for P. falciparum) and co-infection (aOR = 0.10, P = 0.0371) were lower for pupils living in urban area than those living in rural area. Parasitemia of both parasite species were similar in single and co-infection situations (P> 0.05). The interaction between these parasites could involve another mechanism than a competition for blood resources. This study outlined that M. perstans and P. falciparum are co-endemic in the Akonolinga health District. In order to guarantee future success in control and eradication of malaria, a bigger attention should be given to M. perstans or other filarial where it is co-endemic with P. falciparum.
Keywords
Mansonella perstans, Plasmodium falciparum, Co-infection, Interaction, Akonolinga
To cite this article
Leopold Gustave Lehman, Martin Gael Oyono, Samuel Fosso, Charles Félix Bilong Bilong, Mansonella perstans and Plasmodium falciparum Co-infection in the Akonolinga Health District, Centre Region, Cameroon, American Journal of Biomedical and Life Sciences. Vol. 7, No. 1, 2019, pp. 16-21. doi: 10.11648/j.ajbls.20190701.14
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Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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