American Journal of Biomedical and Life Sciences

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Species Diversity of Candida from Hospital Environment in Plateau State, Nigeria

Received: 08 January 2020    Accepted: 20 January 2020    Published: 07 February 2020
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Abstract

In the past few years the role the hospital environment in the transmission of infections has increased leading to the increase in the incidence of morbidity and mortality associated with Candida infections. The hospital environment can serve as an alternative niche for the presence of opportunistic pathogens of public health concern. This study sought to use molecular approach to study the prevalence of Candida from hospital environments in Jos, Plateau State, Nigeria. Samples were collected from different hospital environments and cultured on Chromagar Candida media. Taqman PCR was then used to characterize the isolates, the ability of Candida to form biofilm was evaluated. In this study, Candida parapsilosis with 31.25% was the most prevalent Candida followed by Candida (Nakaseomyces) glabrata and Candida krusei with prevalence of 28.13%. The ability to form biofilms was evaluated for these environmental isolates, and it was observed that C. parapsilosis biofilm formation correlated with high prevalence with C. parapsilosis having high biofilm formation (20/64) followed by C. glabrata and C. krusei (18/64) each Environmental sampling has the potential to improve our knowledge about yeast biodiversity and the evolution of pathogenic yeasts with clinical relevance. This study is the first in Nigeria to study to characterize Candida from hospital environments in Jos, Plateau state Nigeria.

DOI 10.11648/j.ajbls.20200801.14
Published in American Journal of Biomedical and Life Sciences (Volume 8, Issue 1, February 2020)
Page(s) 15-19
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Hospital Environments, Candida, Taqman PCR, Biofilm

References
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Author Information
  • Department of Microbiology, Faculty of Natural and Applied Sciences, Plateau State University, Bokkos, Nigeria

  • Department of Microbiology, Faculty of Natural and Applied Sciences, Plateau State University, Bokkos, Nigeria

  • Department of Microbiology, Faculty of Natural and Applied Sciences, Plateau State University, Bokkos, Nigeria

  • Environmental & Occupational Toxicology Unit, Department of Biochemistry, Faculty of Natural and Applied Sciences, Plateau State University, Bokkos, Nigeria

  • Azerbaijan Medical University, Educational and Therapeutic Hospital, Central Laboratory, Baku, Azerbaijan; Yeditepe University, Faculty and Health Sciences, Department of Nutrition and Dietetics, ?stanbul, Turkey

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    Nnaemeka Emmanuel Nnadi, Miri Alexander Nanpyal, Nanpon Kaduna, Bege Jonathan, Iskender Karalti. (2020). Species Diversity of Candida from Hospital Environment in Plateau State, Nigeria. American Journal of Biomedical and Life Sciences, 8(1), 15-19. https://doi.org/10.11648/j.ajbls.20200801.14

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    Nnaemeka Emmanuel Nnadi; Miri Alexander Nanpyal; Nanpon Kaduna; Bege Jonathan; Iskender Karalti. Species Diversity of Candida from Hospital Environment in Plateau State, Nigeria. Am. J. Biomed. Life Sci. 2020, 8(1), 15-19. doi: 10.11648/j.ajbls.20200801.14

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    AMA Style

    Nnaemeka Emmanuel Nnadi, Miri Alexander Nanpyal, Nanpon Kaduna, Bege Jonathan, Iskender Karalti. Species Diversity of Candida from Hospital Environment in Plateau State, Nigeria. Am J Biomed Life Sci. 2020;8(1):15-19. doi: 10.11648/j.ajbls.20200801.14

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  • @article{10.11648/j.ajbls.20200801.14,
      author = {Nnaemeka Emmanuel Nnadi and Miri Alexander Nanpyal and Nanpon Kaduna and Bege Jonathan and Iskender Karalti},
      title = {Species Diversity of Candida from Hospital Environment in Plateau State, Nigeria},
      journal = {American Journal of Biomedical and Life Sciences},
      volume = {8},
      number = {1},
      pages = {15-19},
      doi = {10.11648/j.ajbls.20200801.14},
      url = {https://doi.org/10.11648/j.ajbls.20200801.14},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajbls.20200801.14},
      abstract = {In the past few years the role the hospital environment in the transmission of infections has increased leading to the increase in the incidence of morbidity and mortality associated with Candida infections. The hospital environment can serve as an alternative niche for the presence of opportunistic pathogens of public health concern. This study sought to use molecular approach to study the prevalence of Candida from hospital environments in Jos, Plateau State, Nigeria. Samples were collected from different hospital environments and cultured on Chromagar Candida media. Taqman PCR was then used to characterize the isolates, the ability of Candida to form biofilm was evaluated. In this study, Candida parapsilosis with 31.25% was the most prevalent Candida followed by Candida (Nakaseomyces) glabrata and Candida krusei with prevalence of 28.13%. The ability to form biofilms was evaluated for these environmental isolates, and it was observed that C. parapsilosis biofilm formation correlated with high prevalence with C. parapsilosis having high biofilm formation (20/64) followed by C. glabrata and C. krusei (18/64) each Environmental sampling has the potential to improve our knowledge about yeast biodiversity and the evolution of pathogenic yeasts with clinical relevance. This study is the first in Nigeria to study to characterize Candida from hospital environments in Jos, Plateau state Nigeria.},
     year = {2020}
    }
    

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  • TY  - JOUR
    T1  - Species Diversity of Candida from Hospital Environment in Plateau State, Nigeria
    AU  - Nnaemeka Emmanuel Nnadi
    AU  - Miri Alexander Nanpyal
    AU  - Nanpon Kaduna
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    UR  - https://doi.org/10.11648/j.ajbls.20200801.14
    AB  - In the past few years the role the hospital environment in the transmission of infections has increased leading to the increase in the incidence of morbidity and mortality associated with Candida infections. The hospital environment can serve as an alternative niche for the presence of opportunistic pathogens of public health concern. This study sought to use molecular approach to study the prevalence of Candida from hospital environments in Jos, Plateau State, Nigeria. Samples were collected from different hospital environments and cultured on Chromagar Candida media. Taqman PCR was then used to characterize the isolates, the ability of Candida to form biofilm was evaluated. In this study, Candida parapsilosis with 31.25% was the most prevalent Candida followed by Candida (Nakaseomyces) glabrata and Candida krusei with prevalence of 28.13%. The ability to form biofilms was evaluated for these environmental isolates, and it was observed that C. parapsilosis biofilm formation correlated with high prevalence with C. parapsilosis having high biofilm formation (20/64) followed by C. glabrata and C. krusei (18/64) each Environmental sampling has the potential to improve our knowledge about yeast biodiversity and the evolution of pathogenic yeasts with clinical relevance. This study is the first in Nigeria to study to characterize Candida from hospital environments in Jos, Plateau state Nigeria.
    VL  - 8
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