| Peer-Reviewed

Study on Risk Factor Evaluation of Ischaemic Stroke Patients Admitted in a Tertiary Care Hospital: 100 Cases

Received: 25 October 2020    Accepted: 12 November 2020    Published: 16 December 2020
Views:       Downloads:
Abstract

Background: Stroke is defined as a sudden onset focal neurological deficit of vascular etiology and is a major cause of mortality and morbidity around the globe. The aim of this study was to find out the proportion of major risk factor or factors related in infarctive stroke cases. Methods: This hospital based descriptive cross sectional study was carried out in one hundred (100) ischemic stroke patients admitted in Medicine units associated with Neurology ward in Enam Medical College & Hospital, Savar, Dhaka, Bangladesh during the period from January 2015 to September 2017. Permission for the study was taken from the mentioned departments and authorities. Subjects were selected in all age groups and both male and female patients to whom duration of illness were less than 72 hours. Results: Among all, 61% were male and 39% were female and male female ratio 1.56:1. The maximum number of patients (36%) were in between 61-70 years of age. Majority of the patients (40%) came from middle class (TK. 7000-10,000/Month). A significant number of patients had high level of lipid profile e.g. Total cholesterol (>200 mg/dl) 73.33%, LDL (>150 mg/dl) 60%, TG (>150 mg/dl) 70%. In many cases multiple risk factors were present. It was observed that hypertension was the most common major risk factor for stroke. Among the 60% of the hypertensive patients only 45% were controlled with treatment and 33.33% were uncontrolled with treatment and 21.66% did not take any medicine or measures. About 47% were smoker. Diabetes mellitus was detected in 26% of patients which is lower than hypertension and hyperlipidaemia. About 25% of patient had history of previous stroke and 20% patient had family history of stroke. Only 6% was alcoholic. Among the female patients 5% received oral pills. Conclusion: Hypertension is one of the major risk factors for the stroke. For the management and prevention of hypertension like stroke, we are recommending the following measures like Hypertension screening programme for early detection, management and follow up and increase awareness regarding hypertension and its complication. It should be controlled by personal motivation, anti-smoking campaign, banding of the smoking propaganda in the TV, Radio, News paper, poster, banner, leaflet etc. Ensure punishment for smoking in open public places and public transports.

Published in American Journal of Biomedical and Life Sciences (Volume 8, Issue 6)
DOI 10.11648/j.ajbls.20200806.16
Page(s) 225-230
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Ischemic, Stroke, Hypertension

References
[1] Bamford J. Clinical examination in diagnosis and subclassification of stroke. The lancet. 1992 Feb 15; 339 (8790): 400-2.
[2] Aho K, Harmsen P, Hatano S, Marquardsen J, Smirnov VE, Strasser T. Cerebrovascular disease in the community: results of a WHO collaborative study. Bulletin of the World Health Organization. 1980; 58 (1): 113.
[3] Kistler JP, Rooper AA, Martin JB. Cerebrovascular diseases Isselbacher KJ, Wilson JD, Braunwald E, et al, editors. Harrison’s Principles of Internal Medicine, 13th ed. New York: McGraw Hill Inc. 1994; 2233-2255.
[4] Swartz MN. Cerebrovascular disease in Cecil Textbook of Medicine, 21st ed. Goldman and Bennett (eds). W. B Saunders Company. 2001; 324: 1645-1654.
[5] Clarke CRA. Cerebrovascular disease and stroke in Kumar & Clark Clinical Medicine, 5th ed. Parveen K, Clark M (eds). W. B. Saunders Company. 2002; 1163-1173.
[6] Mc Caron OM, Delong D, Alberts MJ. APO-E genotype as a risk factor for ischemic cerebrovascular disease. Neurology. 1994; 44: 626-634.
[7] Benson RT, Sacco RL. Stroke prevention: hypertension, diabetes, tobacco, and lipids. Neurologic clinics. 2000 May 1; 18 (2): 309-19.
[8] Poungvarin N. Stroke in the developing world. The Lancet. 1998 Oct 1; 352: S19-22.
[9] Bronner LL, Kanter DS, Manson JE. Primary prevention of stroke. New England Journal of Medicine. 1995 Nov 23; 333 (21): 1392-400.
[10] Elkind MS, Sacco RL. Stroke risk factors and stroke prevention. InSeminars in Neurology 1998 Dec 1 (Vol. 18, No. 4, pp. 429-440). Thieme Medical Publishers.
[11] Bashar A. A dissertation on “Study of risk factors for stroke” 1995; 78-90.
[12] Hossain A, Manadir. Analysis of risk factor for stroke in Hospitalized patient in a Medical College Hospital. 2001.
[13] Roy PK, Arif SM, Alam MR, Khan FD, Ahmad Q, Chowdhury SG. Stroke in patients having inadequate or irregular antihypertensive therapy. Bangladesh Medical Research Council bulletin. 1990 Dec; 16 (2): 52-7.
[14] Sayeed Mohammad Arif. A dissertation on study on risk factor for stroke in Bangladesh. 1993; 55.
[15] Kannel WB, Gordon T, Dawber TR. Role of lipids in the development of brain infarction: the Framingham study. Stroke. 1974 Nov 1; 5 (6): 679-85.
[16] Chapman JM, Reeder LG, Borun ER, Clark VA, Coulson AH. Epidemiology of vascular lesions affecting the central nervous system: The occurrence of strokes in a sample population under observation for cardiovascular disease. American Journal of Public Health and the Nations Health. 1966 Feb; 56 (2): 191-201.
[17] Dalal PM, Shah PM, Aiyar RR, Kikani BJ. Cerebrovascular Diseases in West Central India. Br Med J. 1968 Sep 28; 3 (5621): 769-74.
[18] Pessah-Rasmussen H, Engström G, Jerntorp I, Janzon L. Increasing stroke incidence and decreasing case fatality, 1989–1998: a study from the stroke register in Malmo, Sweden. Stroke. 2003 Apr 1; 34 (4): 913-8.
[19] Alamgir SM, Mannan MA. Cerebrovascular disease (A report of 53 cases). Bangladesh Med Res Coun Bull. 1975; 1: 45-50.
[20] Harmsen P, Rosengren A, Tsipogianni A, Wilhelmsen L. Risk factors for stroke in middle-aged men in Göteborg, Sweden. Stroke. 1990 Feb 1; 21 (2): 223-9.
[21] Kiel Y DK, Hole, Smith GD. Comparison of risk factors for stroke incidence and stroke risk. Am J Epidemiol. 1994; 140: 608-620.
[22] Hart CL, Hole DJ, Smith GD. Comparison of risk factors for stroke incidence and stroke mortality in 20 years of follow-up in men and women in the Renfrew/Paisley Study in Scotland. Stroke. 2000 Aug 1; 31 (8): 1893-6.
[23] Engstrom G, Jerntorp I, Pessah-Rasmussen H, Hedblad B, Berglund G, Janzon L. Geographic distribution of stroke incidence within an urban population: relations to socioeconomic circumstances and prevalence of cardiovascular risk factors. Stroke. 2001 May; 32 (5): 1098-103.
[24] Abbott RD, Yin Y, Reed DM, Yano K. Risk of stroke in male cigarette smokers. New England journal of medicine. 1986 Sep 18; 315 (12): 717-20.
[25] Donnan G, Adena M, O'Malley H, Mcneil J, Doyle A, Neill G. Smoking as a risk factor for cerebral ischaemia. The Lancet. 1989 Sep 16; 334 (8664): 643-7.
[26] Boysen G, Nyboe J, Appleyard M, Sørensen PS, Boas J, Somnier F, Jensen G, Schnohr P. Stroke incidence and risk factors for stroke in Copenhagen, Denmark. Stroke. 1988 Nov 1; 19 (11): 1345-53.
[27] Salonen JT, Puska P, Tuomilehto J, Homan K. Relation of blood pressure, serum lipids, and smoking to the risk of cerebral stroke. A longitudinal study in Eastern Finland. Stroke. 1982 May 1; 13 (3): 327-33.
[28] Latif ZA, Zaman SM, Barua A, Ahad A, Rahim SA. Study of stroke between normotensive and hypertensive NIDDM cases in BIRDEM, Dhaka. Bangladesh journal of Neuroscience. 1990; 6: 52-9.
[29] Iemolo F, Beghi E, Cavestro C, Micheli A, Giordano A, Caggia E. Incidence, risk factors and short-term mortality of stroke in Vittoria, southern Italy. Neurological sciences. 2002 Apr 1; 23 (1): 15-21.
[30] Farley TM, Meirik O, Chang CL, Poulter NR. Combined oral contraceptives, smoking, and cardiovascular risk. Journal of Epidemiology & Community Health. 1998 Dec 1; 52 (12): 775-85.
[31] Walker AE, Robins M, Weinfeld FD. The National Survey of Stroke. Clinical findings. Stroke. 1981; 12 (2 Pt 2 Suppl 1): I13-44.
[32] Morrison AC, Fornage M, Liao D, Boerwinkle E. Parental history of stroke predicts subclinical but not clinical stroke: the Atherosclerosis Risk in Communities Study. Stroke. 2000 Sep 1; 31 (9): 2098-102.
[33] Sigurdsson G, Sigfusson N, Thorsteinsson, Olafsson O, Davidson D, Samielson. Screening for health risks. Acta Med Scand15. 1983; 45-50.
[34] Macfarlane TV, Pigazzani F, Flynn RW, Macdonald TM. The effect of indapamide versus bendroflumethiazide for primary hypertension: a systematic review. British journal of clinical pharmacology. 2018 Oct 12; 296: 1565-70.
[35] Abbott RD, Behrens GR, Sharp DS, Rodriguez BL, Burchfiel CM, Ross GW, Yano K, Curb JD. Body mass index and thromboembolic stroke in nonsmoking men in older middle age. The Honolulu Heart Program. Stroke. 1994 Dec 1; 25 (12): 2370-6.
[36] Shaper AG, Phillips AN, Pocock SJ, Walker M, Macfarlane PW. Risk factors for stroke in middle aged British men. Bmj. 1991 May 11; 302 (6785): 1111-5.
[37] Hayee A, Haque A, Anwarrullah AKM, Akhter N. Analysis of risk factor of stroke in 472 cases. Bangladesh Journal of Neuroscience. 1998; 14 (2): 41-54.
[38] Thompson SBN and Morgan. Epidemiology of stroke. In. Occupational therapy for stroke rehabilitation, 1st ed. Chapman and Hall, London. 1990; 1-14.
[39] Budlie SR. Ischemic stroke. Postgrad Med. 1991; 90: 56-63.
[40] Wong KS. International Prospective Hospital-based study of acute stroke incidence. Lancet. 1998; 352.
[41] Ross RK, Yuan JM, Henderson BE, Park J, Gao YT, Yu MC. Prospective evaluation of dietary and other predictors of fatal stroke in Shanghai, China. Circulation. 1997 Jul 1; 96 (1): 50-5.
[42] Marmot MG, Poulter NR. Primary prevention of stroke. The Lancet. 1992 Feb 8; 339 (8789): 344-7.
Cite This Article
  • APA Style

    Tazin Afrose Shah, Farhan Matin, Anarul Islam, Mahabubur Rahman, Mohiduzzaman Tony, et al. (2020). Study on Risk Factor Evaluation of Ischaemic Stroke Patients Admitted in a Tertiary Care Hospital: 100 Cases. American Journal of Biomedical and Life Sciences, 8(6), 225-230. https://doi.org/10.11648/j.ajbls.20200806.16

    Copy | Download

    ACS Style

    Tazin Afrose Shah; Farhan Matin; Anarul Islam; Mahabubur Rahman; Mohiduzzaman Tony, et al. Study on Risk Factor Evaluation of Ischaemic Stroke Patients Admitted in a Tertiary Care Hospital: 100 Cases. Am. J. Biomed. Life Sci. 2020, 8(6), 225-230. doi: 10.11648/j.ajbls.20200806.16

    Copy | Download

    AMA Style

    Tazin Afrose Shah, Farhan Matin, Anarul Islam, Mahabubur Rahman, Mohiduzzaman Tony, et al. Study on Risk Factor Evaluation of Ischaemic Stroke Patients Admitted in a Tertiary Care Hospital: 100 Cases. Am J Biomed Life Sci. 2020;8(6):225-230. doi: 10.11648/j.ajbls.20200806.16

    Copy | Download

  • @article{10.11648/j.ajbls.20200806.16,
      author = {Tazin Afrose Shah and Farhan Matin and Anarul Islam and Mahabubur Rahman and Mohiduzzaman Tony and Md. Hyder Ali},
      title = {Study on Risk Factor Evaluation of Ischaemic Stroke Patients Admitted in a Tertiary Care Hospital: 100 Cases},
      journal = {American Journal of Biomedical and Life Sciences},
      volume = {8},
      number = {6},
      pages = {225-230},
      doi = {10.11648/j.ajbls.20200806.16},
      url = {https://doi.org/10.11648/j.ajbls.20200806.16},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20200806.16},
      abstract = {Background: Stroke is defined as a sudden onset focal neurological deficit of vascular etiology and is a major cause of mortality and morbidity around the globe. The aim of this study was to find out the proportion of major risk factor or factors related in infarctive stroke cases. Methods: This hospital based descriptive cross sectional study was carried out in one hundred (100) ischemic stroke patients admitted in Medicine units associated with Neurology ward in Enam Medical College & Hospital, Savar, Dhaka, Bangladesh during the period from January 2015 to September 2017. Permission for the study was taken from the mentioned departments and authorities. Subjects were selected in all age groups and both male and female patients to whom duration of illness were less than 72 hours. Results: Among all, 61% were male and 39% were female and male female ratio 1.56:1. The maximum number of patients (36%) were in between 61-70 years of age. Majority of the patients (40%) came from middle class (TK. 7000-10,000/Month). A significant number of patients had high level of lipid profile e.g. Total cholesterol (>200 mg/dl) 73.33%, LDL (>150 mg/dl) 60%, TG (>150 mg/dl) 70%. In many cases multiple risk factors were present. It was observed that hypertension was the most common major risk factor for stroke. Among the 60% of the hypertensive patients only 45% were controlled with treatment and 33.33% were uncontrolled with treatment and 21.66% did not take any medicine or measures. About 47% were smoker. Diabetes mellitus was detected in 26% of patients which is lower than hypertension and hyperlipidaemia. About 25% of patient had history of previous stroke and 20% patient had family history of stroke. Only 6% was alcoholic. Among the female patients 5% received oral pills. Conclusion: Hypertension is one of the major risk factors for the stroke. For the management and prevention of hypertension like stroke, we are recommending the following measures like Hypertension screening programme for early detection, management and follow up and increase awareness regarding hypertension and its complication. It should be controlled by personal motivation, anti-smoking campaign, banding of the smoking propaganda in the TV, Radio, News paper, poster, banner, leaflet etc. Ensure punishment for smoking in open public places and public transports.},
     year = {2020}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Study on Risk Factor Evaluation of Ischaemic Stroke Patients Admitted in a Tertiary Care Hospital: 100 Cases
    AU  - Tazin Afrose Shah
    AU  - Farhan Matin
    AU  - Anarul Islam
    AU  - Mahabubur Rahman
    AU  - Mohiduzzaman Tony
    AU  - Md. Hyder Ali
    Y1  - 2020/12/16
    PY  - 2020
    N1  - https://doi.org/10.11648/j.ajbls.20200806.16
    DO  - 10.11648/j.ajbls.20200806.16
    T2  - American Journal of Biomedical and Life Sciences
    JF  - American Journal of Biomedical and Life Sciences
    JO  - American Journal of Biomedical and Life Sciences
    SP  - 225
    EP  - 230
    PB  - Science Publishing Group
    SN  - 2330-880X
    UR  - https://doi.org/10.11648/j.ajbls.20200806.16
    AB  - Background: Stroke is defined as a sudden onset focal neurological deficit of vascular etiology and is a major cause of mortality and morbidity around the globe. The aim of this study was to find out the proportion of major risk factor or factors related in infarctive stroke cases. Methods: This hospital based descriptive cross sectional study was carried out in one hundred (100) ischemic stroke patients admitted in Medicine units associated with Neurology ward in Enam Medical College & Hospital, Savar, Dhaka, Bangladesh during the period from January 2015 to September 2017. Permission for the study was taken from the mentioned departments and authorities. Subjects were selected in all age groups and both male and female patients to whom duration of illness were less than 72 hours. Results: Among all, 61% were male and 39% were female and male female ratio 1.56:1. The maximum number of patients (36%) were in between 61-70 years of age. Majority of the patients (40%) came from middle class (TK. 7000-10,000/Month). A significant number of patients had high level of lipid profile e.g. Total cholesterol (>200 mg/dl) 73.33%, LDL (>150 mg/dl) 60%, TG (>150 mg/dl) 70%. In many cases multiple risk factors were present. It was observed that hypertension was the most common major risk factor for stroke. Among the 60% of the hypertensive patients only 45% were controlled with treatment and 33.33% were uncontrolled with treatment and 21.66% did not take any medicine or measures. About 47% were smoker. Diabetes mellitus was detected in 26% of patients which is lower than hypertension and hyperlipidaemia. About 25% of patient had history of previous stroke and 20% patient had family history of stroke. Only 6% was alcoholic. Among the female patients 5% received oral pills. Conclusion: Hypertension is one of the major risk factors for the stroke. For the management and prevention of hypertension like stroke, we are recommending the following measures like Hypertension screening programme for early detection, management and follow up and increase awareness regarding hypertension and its complication. It should be controlled by personal motivation, anti-smoking campaign, banding of the smoking propaganda in the TV, Radio, News paper, poster, banner, leaflet etc. Ensure punishment for smoking in open public places and public transports.
    VL  - 8
    IS  - 6
    ER  - 

    Copy | Download

Author Information
  • Department of Medicine, Uttara Adhunik Medical College (UAMC), Dhaka, Bangladesh

  • Department of Radiology and Imaging, Uttara Adhunik Medical College (UAMC), Dhaka, Bangladesh

  • Department of Respiratory Medicine, Uttara Adhunik Medical College (UAMC), Dhaka, Bangladesh

  • Department of Gastroenterology, Uttara Adhunik Medical College (UAMC), Dhaka, Bangladeshs

  • Department of Surgery, Uttara Adhunik Medical College (UAMC), Dhaka, Bangladesh

  • Department of Medicine, Uttara Adhunik Medical College (UAMC), Dhaka, Bangladesh

  • Sections