Cytotoxic, Acute Toxicity and Phytotoxic Activity of Callicarpa macrophylla in Various Models
American Journal of Biomedical and Life Sciences
Volume 3, Issue 2-1, March 2015, Pages: 1-4
Received: Oct. 21, 2014;
Accepted: Oct. 30, 2014;
Published: Nov. 5, 2014
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Barkatullah , Department of Botany, University of Peshawar, Peshawar-25120, Pakistan
Muhammad Ibrar, Department of Botany, University of Peshawar, Peshawar-25120, Pakistan
Muhammad Nafees, Department of Botany, University of Peshawar, Peshawar-25120, Pakistan
Abdur Rauf, Institute of Chemical Sciences, University of Peshawar, Peshawar-25120, KPK, Pakistan
Haroon Khan, Department of Pharmacy, Abdul Wali Khan University Mardan-23200, Pakistan
The present study describes the cytotoxic, acute toxicity and phytotoxic activities of Callicarpa macrophylla belonging to family Verbanaceae. Brine shrimps cytotoxic bioassay of crude extract of bark of C. macrophylla (CBE) showed 975.22 LD50 value and crude extract of leaves of C. macrophylla (CLE) showed no significant results. However, all the test animals were found absolutely safe in acute toxicity test. In phytotoxic assay against Lemna minor, CLE showed FI50 value of 464.55 and CBE showed no significant results. In conclusion, the CLE showed significant phytotoxic activity and therefore, could be a useful natural herbicidal.
Cytotoxic, Acute Toxicity and Phytotoxic Activity of Callicarpa macrophylla in Various Models, American Journal of Biomedical and Life Sciences. Special Issue: Phytochemical and Pharmacological Study of Medicinal Plants.
Vol. 3, No. 2-1,
2015, pp. 1-4.
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