Frequency, Causes and Cutting-Edge Treatment of Cataract: A Review
American Journal of Biomedical and Life Sciences
Volume 3, Issue 2-1, March 2015, Pages: 25-28
Received: Jan. 19, 2015; Accepted: Jan. 20, 2015; Published: Feb. 15, 2015
Views 3513      Downloads 189
Authors
Latifullah Khan, Department of Biotechnology, Faculty of Biological Sciences University of Science & Technology, Bannu KPK, Pakistan
Rahmat Ali Khan, Department of Biotechnology, Faculty of Biological Sciences University of Science & Technology, Bannu KPK, Pakistan
Wasim Ahmed, Department of Biotechnology, Faculty of Biological Sciences University of Science & Technology, Bannu KPK, Pakistan
Abdur Rauf, Institute of Chemical Sciences, University of Peshawar, Peshawar (25120), KPK, Pakistan
M. Waqas Khan, Department of Biotechnology, Faculty of Biological Sciences University of Science & Technology, Bannu KPK, Pakistan
Wasiullah Khan, Department of Biotechnology, Faculty of Biological Sciences University of Science & Technology, Bannu KPK, Pakistan
Samran Ahmad Durrani, Department of Biotechnology, Faculty of Biological Sciences University of Science & Technology, Bannu KPK, Pakistan
Saad Qayum, Department of Biotechnology, Faculty of Biological Sciences University of Science & Technology, Bannu KPK, Pakistan
Article Tools
Follow on us
Abstract
Cataract is the disease which is prevailing world wide rapidly and health care professionals are making serious efforts to investigate the latest, inexpensive and readily available treatment of the disease. The aim of this review was to investigate the pervasiveness, causes and latest treatment of cataract. However this is a cross sectional study in which we study that Cataract occurs when protein is buildup in the lens and makes it cloudy. So the passing of light clearly through the lens is disturbed thus vision is lost up to some extent. Since on the outside of the lens new lens cells are formed, all the older cells are compacted into the center of the lens resulting in the cataract. Beside of this oxygen free radicals are also involved in cataract because its overproduction can stop the reach of glutathione and other antioxidant into lens where it ceases action of oxidant. Genetically prevalence of cataract also possessed. The gene responsible for cataract is Gamma-S crystalline gene (CRYGS).The only way of cataract removal is surgery although some medication are also present but it is not enough evidence that these lowers the risk for cataract formation.
Keywords
Cataract, Lens, Gamma-S crystalline gene, Medication
To cite this article
Latifullah Khan, Rahmat Ali Khan, Wasim Ahmed, Abdur Rauf, M. Waqas Khan, Wasiullah Khan, Samran Ahmad Durrani, Saad Qayum, Frequency, Causes and Cutting-Edge Treatment of Cataract: A Review, American Journal of Biomedical and Life Sciences. Special Issue: Phytochemical and Pharmacological Study of Medicinal Plants. Vol. 3, No. 2-1, 2015, pp. 25-28. doi: 10.11648/j.ajbls.s.2015030201.14
References
[1]
Resnikoff S, Pascolini D, Etya’ale D. Global data on visual impairment in the year 2002. Bull World Health Organ 2004; 82: 844–51.
[2]
World Health Organization. Global initiative for the elimination of avoidable blindness. Geneva: WHO, WHO/PBL/97.61
[3]
Limburg H, Vasavada A, Muzumdar G. Rapid assessment of cataract blindness in urban district of Gujarat. Indian J Ophthalmol 1999; 47: 135–41.
[4]
Foster A. Cataract—a global perspective: output, outcome and outlay. Eye 1999; 13: 449–53.
[5]
Johnson GJ. Improving outcome of cataract surgery in developing countries. Lancet 2000; 355: 158–9.
[6]
Memon MS. Prevalence and causes of blindness in Pakistan. J Pak Med Assoc 1992; 42: 196–8.
[7]
Ahmad K, Khan MD, Qureshi MB, et al. Prevalence and causes of blindness and low vision in a rural setting in Pakistan. Ophthalmic Epidemiol 2005; 12: 19–23.
[8]
Clayton RM, Cuthbert J, Seth J, Phillips CI, Bartholomew RS, Reid JMcK: Epidemiological and other studies in the assessment of factors contributing to cataractogenesis. Ciba Symp 1984, 106: 25-47.
[9]
Van Heyningen R and Harding JJ: Do aspirin-like analgesics protect against cataract? A case-control study. Lancet 1986, i: 1111- l3.
[10]
Halevi HS and Landau 1: Hospitalized senile cataract in different lewish communities in Israel. Brit Ophthalmol 1962, 46: 285-90.
[11]
Kahn HA, Leibowitz HM, Ganley lP, Kini MM, Colton T, Nickerson RS, Dawber TR: The Framingham Eye Study II. Association of ophthalmic pathology with single variables previously measured in the Framingham Heart Study. Am] EpidemioI1977, 106: 33-41
[12]
Van Heyningen R and Harding JJ: Risk factors for cataract: diabetes, myopia and sex. Colloq. INSERM 1986, 147: 381-5.
[13]
American Academy of Ophthalmology. Cataract in the Adult Eye, Preferred Practice Pattern. San Francisco: American Academy of Ophthalmology, 2006. Accessed July 1, 2008.
[14]
University of Maryland Medical center http://umm.edu/health/medical/reports/articles/cataracts
[15]
http://en.wikipedia.org/wiki/Cataract#Genetics
[16]
Hammond CJ, Snieder H, Spector TD, Gilbert CE. Genetic and environmental factors in age-related nuclear cataracts in monozygotic and dizygotic twins. N Engl J Med 2000; 342: 1786–90.
[17]
Hammond CJ, Duncan DD, Snieder H, de Lange M, West SK, Spector TD, Gilbert CE. The heritability of age-related cortical cataract: the Twin Eye Study. Invest Ophthalmol Vis Sci 2001; 42: 601–5.
[18]
Bollinger KE, Langston RH (2008). "What can patients expect from cataract surgery?". Cleveland Clinic journal of medicine75 (3): 193–196, 199–196. doi: 10.3949/ccjm.75.3.193.PMID 18383928
[19]
"Posterior Subcapsular Cataract". Digital Reference of Ophthalmology. Edward S. Harkness Eye Institute, Department of Ophthalmology of Columbia University. 2003. Retrieved 2 April 2013
[20]
Spencer RW, Andelman SY (1965). "Steroid cataracts. Posterior subcapsular cataract formation in rheumatoid arthritis patients on long term steroid therapy". Arch Ophthalmol 74: 38–41.
[21]
Greiner JV, Chylack LT (1979). "Posterior subcapsular cataracts: histopathologic study of steroid-associated cataracts". Arch Ophthalmol 97 (1): 135–44.
[22]
Finger, Stanley (1994). Origins of Neuroscience: A History of Explorations Into Brain Function. Oxford University Press. p. 70.ISBN 0-19-514694-8
[23]
Aulus Cornelius Celsus, G. F. Collier (transl.) (1831). De Medicinae. OL 5225311W.
[24]
Elliott, Jane (February 9, 2008). "The Romans carried out cataract ops". BBC News.
[25]
Suśruta, P. V. Sharma (trans.) (2000). Suśruta-Saṃhitā 1. Varanasi: Caukhambha Visvabharati. p. iv. OL 160267M.
[26]
Online Etymology Dictionary, etymonline.com
[27]
Fernandez MM, Afshari NA. Nutrition and the prevention of cataracts. Curr Opin Ophthalmol. 2008 Jan; 19(1):66-70.
[28]
Williams DL, Munday P (2006). "The effect of a topical antioxidant formulation including N-acetyl carnosine on canine cataract: a preliminary study". Vet Ophthalmol 9 (5): 311–6.
[29]
Guo Y, Yan H (2006). "Preventive effect of carnosine on cataract development". Yan Ke Xue Bao 22 (2): 85–8.
[30]
Fernandez MM, Afshari NA. Nutrition and the prevention of cataracts. Curr Opin Ophthalmol. 2008 Jan; 19(1): 66-70.
[31]
Spencer RW, Andelman SY (1965). "Steroid cataracts. Posterior subcapsular cataract formation in rheumatoid arthritis patients on long term steroid therapy". Arch Ophthalmol 74: 38–41.
[32]
Dr. Kushal Banerjee (2006). "A review and clinical evaluation of per-operative and post-operative complications in case of manual small incision cataract surgery and extracapsular cataract extraction with posterior chamber intra-ocular lens implantation". Retrieved1 June 2014.
ADDRESS
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
U.S.A.
Tel: (001)347-983-5186