Normo Hyper and Extreme Hypercomplementemia in Human Chronic Periodontitis
American Journal of Biomedical and Life Sciences
Volume 3, Issue 4-1, July 2015, Pages: 4-6
Received: Feb. 11, 2015; Accepted: Feb. 13, 2015; Published: Mar. 2, 2015
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Authors
Ibrahim M. S. Shnawa, College of Biotechnology, University of Kasim , Kasim , Babylon / IRAQ
Baha H. H. Alamiedi, Department of Basic Sciences, College of Dentistry, University of Babylon , Babylon / IRAQ
Zainab M. H. Al Fatlawy, Department of Oral Medicine, College of Dentistry, University of Babylon , Babylon / IRAQ
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Abstract
Fourty-Nine chronic periodontitis patients were diagnosed by the dentist of the team. Of which 27 were generalized chronic and the other 22 were localized chronic periodontitis. Ten subjects with normal mouth hygienewere considered as controls. Blood,and saliva samples were collected from both of the test patients and controls. Sera, saliva and salivary proteins were subjected to C3 and C4 determinations using ready made plates ofradial immunodiffusion in gel containing anti-C3 and anti-C4 antibodies. Generalized chronic periodontitis patients were showing higher C3 levels than localized chronic periodontitis patients. Both of thedisease forms were of higher C3 and C4 levels than controls. Females have lower C3 levels than male chronic periodontitis patients. C4 levels were slightly increased than normal control levels. Male C4 levels approximate female levels. Four cases ofC3 and C4 hypercomplementemia in each of the disease forms.One extremecombinedC3 and C4 hypercomplementemia in the generalized form and one extreme C4 hypercomplementemiawas noted in the localized form. Thus, normo, hyper and extreme hypercomplementemia C3 and C4 were noted among chronic periodontitis patients. These hypercomplementemia cases are secondary non-genetic, infection and /or inflammation induced.
Keywords
Chronic, Complement C3 and C4, Localized, Generalized, Periodontitis
To cite this article
Ibrahim M. S. Shnawa, Baha H. H. Alamiedi, Zainab M. H. Al Fatlawy, Normo Hyper and Extreme Hypercomplementemia in Human Chronic Periodontitis, American Journal of Biomedical and Life Sciences. Special Issue: Advances in Oral Immunity. Vol. 3, No. 4-1, 2015, pp. 4-6. doi: 10.11648/j.ajbls.s.2015030401.12
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