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Frequency of Cardiovascular Risk Factors in Adult Nigerians with Family History of Non-Communicable Cardiovascular Disease in a Primary Care Clinic of a Tertiary Hospital in a Resource-Constrained Environment of Eastern Nigeria

Received: 27 July 2013    Accepted:     Published: 20 August 2013
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Abstract

Background: Cardiovascular (CV) risk factors tend to cluster in persons with family history of cardiovascular diseases (CVDs) with variable distribution and penetrance. Screening adult Nigerians with immutable family history of CVD for other conventional CV risk factors is an important primary care challenge that is often neglected especially in resource-constrained settings. Aim: This study was designed to determine the frequency of cardiovascular risk factors in adult Nigerians with family history of non-communicable cardiovascular disease in a primary care clinic of a tertiary hospital in a resource-constrained environment of Eastern Nigeria. Materials and Methods: A descriptive facility-based study carried out on 440 consecutive adult Nigerians with family history of at least one of the major non-communicable CVDs in Nigeria who were screened for CV risk factors. Basic demographic variables, cardio-metabolic and behavioural risk factors were obtained using a pretested, structured and researcher-administered questionnaire. The conventional CV risk factors studied were hypertension, obesity, diabetes mellitus, physical activity, alcohol and tobacco use. Family history of CVD refers to previous information on any major CVDs such as hypertension, heart failure, myocardial infarction and stroke in any of the first, second and third degree generation family members who were dead or alive made by a health professional. Results: The three most frequent cardiovascular risk factors were physical inactivity (81.6%), asymptomatic hypertension (26.4%) and obesity (18.9%). Others included alcohol use (17.5%), diabetes mellitus (7.7%) and tobacco use (5.7%). Conclusion: This study has shown that CV risk factors exist among the study population with three most common being physical inactivity, asymptomatic hypertension and obesity. Screening adult Nigerians with family history of CVD for cardio-metabolic and behavioural CV risk factors should form baseline evaluation for these patients during clinical encounter in primary care.

Published in American Journal of Health Research (Volume 1, Issue 1)
DOI 10.11648/j.ajhr.20130101.13
Page(s) 17-25
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Adult Nigerians, Family History of CVD, Primary Care, CV Risk Factors

References
[1] Yach D, Hawkees C, Gouuld CL, Hofman KJ. The global burden of chronic diseases: overcoming the impediments to prevention and control. JAMA 2004; 291: 2616-2622.
[2] Lawoyin TO, Asuzu MC, Kaufman J, Rotimi C, Owoaje E, Johnson L, Cooper R. Prevalence of cardiovascular factors in an African urban inner city community. West Afr J Med 2002; 21: 208-211.
[3] Kadiri S. Tackling cardiovascular diseases in Africa. BMJ, West Africa edition 2005;8: 172-173.
[4] Gaziano TA, Gaziano JM. Epidemiology of cardiovascular diseases. In Fauci AS, Braunwald E, Kasper DL, Hauser SI, Longo DL, Jameson JL and Loscalzo J editors. Harrison’s Principles of Internal Medicine, 17th edn. New York, McGraw Hill Medical 2008: p. 1375-1379.
[5] Gaziano JM. Global burden of cardiovascular disease. In Braunwald Heart disease: A Textbook of cardiovascular Medicine, 8th edn. Philadelphia, Elservier Saunders 2008: p. 3-20.
[6] Iloh GP, Ikwudinma AO, Obiegbu NP. Obesity and its cardio-metabolic co-morbidities among adult Nigerians in a primary care clinic of a tertiary hospital in South-Eastern Nigeria. J Fam Med Primary Care 2013; 2: 20-26
[7] Ogah OS, Okpechi I, Chukwuonye II, Akinyemi JO, Onwubere BJC, Falase AO, Stewart S, Sliwa K. Blood pressure, prevalence of hypertension and hypertension related complications in Nigerian Africans: A review. World J Cardiol 2012; 4: 327-340.
[8] Pandve HT, Chawla PS, Fernandez K. Recent developments in cardiovascular diseases control and prevention in India. J Fam Med Primary Care 2012; 1: 79-80.
[9] Al-Baghli NA, AL-Ghamdi AJ, Al-Turki KA, El-Zubaier AG, Al-Mostafa BA, Al-Baghli FA, Al-Ameer MM. Awareness of cardiovascular disease in eastern Saudi Arabia. J Fam Community Med 2010; 17: 15-21.
[10] Arodiwe EB, Ike SO, Nwokediuko SC. Case fatality among hypertension-related admissions in Enugu, Nigeria. Niger J Clin Pract 2009; 12: 153-156.
[11] Akinkugbe OO. Non-communicable diseases in Nigeria. The next epidemics; Abayomi Memorial Lectures. Niger J Med Pract 2000; 3: 904-907.
[12] Oghagbon EK, Okesina AB. Pattern of some risk factors for cardiovascular disease in untreated Nigerian hypertensive patients. West Afr J Med 2006; 25: 190-194.
[13] Akindele MO, Uba M. Incidence and Pattern of Cardiovascular Disease in North Western Nigeria. Niger Med J 2009; 50: 55-57.
[14] Kengne AP, Awah PK, Fezeu L, Mbanya JC. The burden of high blood pressure and related risk factors in urban sub-Saharan Africa: Evidences from Douala in Cameroon. Afr Health Sci 2007; 7: 38-44.
[15] Yusuf S, Reddy S, Ounpuu S, Anand S. Global burden of cardiovascular diseases: Part II: variations in cardiovascular disease by specific ethnic groups and geographic regions and prevention strategies. Circulation 2001; 104: 2855-2864.
[16] Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of high blood pressure: The JNC VII report. JAMA 2003; 289: 2560- 2572.
[17] Sani MU, Wahab KW, Yusuf BO, Gbadamosi M, Johnson OV, Gbadamosi A. Modifiable cardiovascular risk factors among apparently healthy adult Nigerian population-a cross sectional study. BMC Res Notes 2010; 3:11.
[18] Keddy KS. Cardiovascular diseases in the developing countries: dimensions, determinants, dynamics and direction for public health action. Public Health Nutr 2002; 5: 231-237.
[19] Magnus P, Beaglehole R. The real contribution of the major risk factors to the coronary epidemics: Time to end the ‘’Only 50%’’ Myth. Arch Intern Med 2001; 161: 2657-2660.
[20] Rich EC, Burke W, Henton CJ, Haga S, Pinsky L, Short P, et al. Reconsidering the family history in primary care. J Gen Intern Med 2004; 19: 273-280.
[21] Ike SO, Arodiwe EB, Onoka CA. Profile of Cardiovascular Risk Factors among Priests in a Nigerian Rural Community. Niger Med J 2007; 48: 79-84.
[22] Nwachukwu L, Inem V, Ajuluchukwu JNA, Ayankogbe OO, Jarikre A. Cardiovascular Risk Factors in Nigerian Company Executives Presenting for Group Life Assurance Policy. Niger Hospital Pract 2007; 1: 13-16.
[23] Yoon PW, Scheuner MT, Peterson-oehlke KL, Gwinn M, Faucett A, Khoury MJ. Can family history be used as a tool for public health and preventive medicine? Genet Med 2002; 4: 304-310.
[24] Keddy KS, Katan MB. Diet, Nutrition and the prevention of hypertension and cardiovascular diseases. Public Health Nutr 2004; 7(1A): 167-186.
[25] World Health Organization. Preventing chronic diseases: a vital investment. Geneva. World Health Organization 2005.
[26] Dominguez LJ, Galioto A, Ferlisi A, Pineo A, Putignario E, Belvedera M. Aging, lifestyle modifications and cardiovascular disease in developing countries. J Nutr Health Aging 2006; 10: 143- 9.
[27] Araoye MO. Sample size determination. Research Methodology with Statistics for Health and Social Sciences, Ilorin, Nathadex Publishers, 2004; p.115-121.
[28] Onwubere B, Kadiri S. Guidelines for the management of hypertension in Nigeria. Nigerian Hypertension Society. Enugu, Ezu Books Limited 2005.p. 1-40
[29] WHO. Survey of the STEPwise approach for the survellaince of risk factors for non-communicable diseases, Brazzaville, WHO, Region office for Africa, 2007.
[30] Myers J. Exercise and Cardiovascular Health. Circulation 2003; 107: 2.
[31] Lee IM. Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy. Lancet 2012; 380: 219-229.
[32] Wessel TR, Arant CB, Olson MB, Johnson BD, Reis SE, Sharaf BL, et al. Relationship of physical fitness vs body mass index with coronary artery disease and cardiovascular events in women. JAMA 2004; 292: 1179-1187.
[33] Sobngwi E, Mbanya JC, Unwin NC. Physical activity and its relationship with obesity, hypertension and diabetes in urban and rural Cameroon. Int J Obes.Relat Metab Disord 2003; 26: 1009-1016.
[34] WHO. Global strategy on diet, physical activity and health. Bulletins of the WHO 2006; 5: 16-18.
[35] Warburton DER, Nicol CW, Bredin SSD. Health benefits of physical exercise: the evidence. CMAJ 2006; 174: 801-809.
[36] Adamu B, Sani MU, Abdu A. Physical Exercise and Health: A Review. Niger J Med 2006; 15: 190-196.
[37] Ogah OS, Madukwe OO, Chukwuonye II, Onyeonoro UU, Ukaegbu AU, Akhimien MO et al. Prevalence and determinants of hypertension in Abia State Nigeria: results from the Abia State Non-Communicable Diseases and Cardiovascular Risk Factors Survey. Ethn Dis 2013; 23: 161-167.
[38] Oke DA, Bandele EO. Misconception of hypertension. J Natl Med Assoc 2004; 96: 1221-1224.
[39] Omuemu VO, Okojie OH, Omuemu CE. Awareness of high blood pressure status, treatment and control in a rural community in Edo state. Niger J Clin Pract 2007; 10:208-212.
[40] Iloh GUP, Ofoedu JN, Njoku PU, Amadi AN, Godswill-Uko EU. Medication adherence and blood pressure control amongst adults with primary hypertension attending a tertiary hospital primary care clinic in Eastern Nigeria. African Journal of Primary Health Care & Family Medicine 2013 ;5: 446.
[41] Cooper RS, Amoah AG, Mensah GA. High blood pressure: the foundation for epidemic cardiovascular diseases in African population. Ethn Dis 2003; 13(2 Suppl 2): S48-52
[42] Bhatt DL, Steg PG, Ohman EM. International prevalence, recognition and treatment of cardiovascular risk factors in outpatients with atherothrombosis. JAMA 2006; 295: 180-189.
[43] Iloh GUP, Amadi AN, Chuku A. Burden of non-communicable diseases among geriatric Nigerians in a rural hospital in resource-constrained setting of Eastern Nigeria. Science Journal of Public Health 2013; 1: 141-146.
[44] Caulfield M, Munroe P, Pembroke J, Samani N, Dominiczak A, Brown M, et al. Genome-wide mapping of human loci for essential hypertension. Lancet 2003; 361: 2118-2123.
[45] Yoon PW, Scheuner MT, Khoury MJ. Research priorities for evaluating family history in the prevention of common chronic diseases. Am J Prev Med 2003; 24:128-135.
[46] Goldstein IB, Shapiro D, Guthrie D. Ambulatory blood pressure and family history of hypertension in healthy men and women. Am J Hypertens 2006; 19: 486-491.
[47] Chukwuonye II, Chuku A, John C, Ohagwu KA, Imoh ME, Isa SE, Ogah OS, Oviasu E. Prevalence of overweight and obesity in adult Nigerians-a systematic review. Diabetes Metabolic Syndrome and Obesity: Targets and Therapy 2013; 6: 43-47.
[48] Ogunbode AM, Ladipo M, Ajayi IO, Fatiregun AA. Obesity: A emerging disease. Niger J Clin Pract 2011; 14: 390-394.
[49] Iloh GUP, Amadi AN, Nwankwo BO. Obesity in adult Nigerians: a study of its prevalence and common primary co-morbidities in a semi-urban Mission General Hospital in South-Eastern Nigeria. Niger J Med 2010; 19: 459-466.
[50] Iloh GUP, Amadi AN, Nwankwo BO, Ugwu VC. Obesity in adult Nigerians: A study of its pattern and common primary co-morbidities in a rural Mission General Hospital in Imo state, south-eastern Nigeria. Niger J Clin Pract 2011; 14: 212-218.
[51] Oyekan AO. Genetics of Food Intake, Body Weight and Obesity-Role of Leptin. Niger Med Pract 2005; 47: 108-112.
[52] WHO. Innovative care for chronic conditions: building blocks for action. Geneva: World Health Organization, 2002.
Cite This Article
  • APA Style

    Gabriel Uche Pascal Iloh, Abali Chuku, Nnadozie Paul Obiegbu, John Nnaemeka Ofoedu, Augustin Obiora Ikwudinma. (2013). Frequency of Cardiovascular Risk Factors in Adult Nigerians with Family History of Non-Communicable Cardiovascular Disease in a Primary Care Clinic of a Tertiary Hospital in a Resource-Constrained Environment of Eastern Nigeria. American Journal of Health Research, 1(1), 17-25. https://doi.org/10.11648/j.ajhr.20130101.13

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    ACS Style

    Gabriel Uche Pascal Iloh; Abali Chuku; Nnadozie Paul Obiegbu; John Nnaemeka Ofoedu; Augustin Obiora Ikwudinma. Frequency of Cardiovascular Risk Factors in Adult Nigerians with Family History of Non-Communicable Cardiovascular Disease in a Primary Care Clinic of a Tertiary Hospital in a Resource-Constrained Environment of Eastern Nigeria. Am. J. Health Res. 2013, 1(1), 17-25. doi: 10.11648/j.ajhr.20130101.13

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    AMA Style

    Gabriel Uche Pascal Iloh, Abali Chuku, Nnadozie Paul Obiegbu, John Nnaemeka Ofoedu, Augustin Obiora Ikwudinma. Frequency of Cardiovascular Risk Factors in Adult Nigerians with Family History of Non-Communicable Cardiovascular Disease in a Primary Care Clinic of a Tertiary Hospital in a Resource-Constrained Environment of Eastern Nigeria. Am J Health Res. 2013;1(1):17-25. doi: 10.11648/j.ajhr.20130101.13

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  • @article{10.11648/j.ajhr.20130101.13,
      author = {Gabriel Uche Pascal Iloh and Abali Chuku and Nnadozie Paul Obiegbu and John Nnaemeka Ofoedu and Augustin Obiora Ikwudinma},
      title = {Frequency of Cardiovascular Risk Factors in Adult Nigerians with Family History of Non-Communicable Cardiovascular Disease in a Primary Care Clinic of a Tertiary Hospital in a Resource-Constrained Environment of Eastern Nigeria},
      journal = {American Journal of Health Research},
      volume = {1},
      number = {1},
      pages = {17-25},
      doi = {10.11648/j.ajhr.20130101.13},
      url = {https://doi.org/10.11648/j.ajhr.20130101.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20130101.13},
      abstract = {Background: Cardiovascular (CV) risk factors tend to cluster in persons with family history of cardiovascular diseases (CVDs) with variable distribution and penetrance. Screening adult Nigerians with immutable family history of CVD for other conventional CV risk factors is an important primary care challenge that is often neglected especially in resource-constrained settings. Aim: This study was designed to determine the frequency of cardiovascular risk factors in adult Nigerians with family history of non-communicable cardiovascular disease in a primary care clinic of a tertiary hospital in a resource-constrained environment of Eastern Nigeria. Materials and Methods: A descriptive facility-based study carried out on 440 consecutive adult Nigerians with family history of at least one of the major non-communicable CVDs in Nigeria who were screened for CV risk factors.  Basic demographic variables, cardio-metabolic and behavioural risk factors were obtained using a pretested, structured and researcher-administered questionnaire.  The conventional CV risk factors studied were hypertension, obesity, diabetes mellitus, physical activity, alcohol and tobacco use. Family history of CVD refers to previous information on any major CVDs such as hypertension, heart failure, myocardial infarction and stroke in any of the first, second and third degree generation family members who were dead or alive made by a health professional. Results: The three most frequent cardiovascular risk factors were physical inactivity (81.6%), asymptomatic hypertension (26.4%) and obesity (18.9%). Others included alcohol use (17.5%), diabetes mellitus (7.7%) and tobacco use (5.7%). Conclusion: This study has shown that CV risk factors exist among the study population with three most common being physical inactivity, asymptomatic hypertension and obesity. Screening adult Nigerians with family history of CVD for cardio-metabolic and behavioural CV risk factors should form baseline evaluation for these patients during clinical encounter in primary care.},
     year = {2013}
    }
    

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  • TY  - JOUR
    T1  - Frequency of Cardiovascular Risk Factors in Adult Nigerians with Family History of Non-Communicable Cardiovascular Disease in a Primary Care Clinic of a Tertiary Hospital in a Resource-Constrained Environment of Eastern Nigeria
    AU  - Gabriel Uche Pascal Iloh
    AU  - Abali Chuku
    AU  - Nnadozie Paul Obiegbu
    AU  - John Nnaemeka Ofoedu
    AU  - Augustin Obiora Ikwudinma
    Y1  - 2013/08/20
    PY  - 2013
    N1  - https://doi.org/10.11648/j.ajhr.20130101.13
    DO  - 10.11648/j.ajhr.20130101.13
    T2  - American Journal of Health Research
    JF  - American Journal of Health Research
    JO  - American Journal of Health Research
    SP  - 17
    EP  - 25
    PB  - Science Publishing Group
    SN  - 2330-8796
    UR  - https://doi.org/10.11648/j.ajhr.20130101.13
    AB  - Background: Cardiovascular (CV) risk factors tend to cluster in persons with family history of cardiovascular diseases (CVDs) with variable distribution and penetrance. Screening adult Nigerians with immutable family history of CVD for other conventional CV risk factors is an important primary care challenge that is often neglected especially in resource-constrained settings. Aim: This study was designed to determine the frequency of cardiovascular risk factors in adult Nigerians with family history of non-communicable cardiovascular disease in a primary care clinic of a tertiary hospital in a resource-constrained environment of Eastern Nigeria. Materials and Methods: A descriptive facility-based study carried out on 440 consecutive adult Nigerians with family history of at least one of the major non-communicable CVDs in Nigeria who were screened for CV risk factors.  Basic demographic variables, cardio-metabolic and behavioural risk factors were obtained using a pretested, structured and researcher-administered questionnaire.  The conventional CV risk factors studied were hypertension, obesity, diabetes mellitus, physical activity, alcohol and tobacco use. Family history of CVD refers to previous information on any major CVDs such as hypertension, heart failure, myocardial infarction and stroke in any of the first, second and third degree generation family members who were dead or alive made by a health professional. Results: The three most frequent cardiovascular risk factors were physical inactivity (81.6%), asymptomatic hypertension (26.4%) and obesity (18.9%). Others included alcohol use (17.5%), diabetes mellitus (7.7%) and tobacco use (5.7%). Conclusion: This study has shown that CV risk factors exist among the study population with three most common being physical inactivity, asymptomatic hypertension and obesity. Screening adult Nigerians with family history of CVD for cardio-metabolic and behavioural CV risk factors should form baseline evaluation for these patients during clinical encounter in primary care.
    VL  - 1
    IS  - 1
    ER  - 

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Author Information
  • Department of Family Medicine, Federal Medical Centre, Umuahia, Abia state, Nigeria

  • Department of Ophthalmology Federal Medical Centre, Umuahia, Abia state, Nigeria

  • Ministry of Health, Awka, Anambra State, Nigeria and Trainer in Family Medicine Residency program, Department of Family Medicine, Federal Medical Centre, Umuahia, Nigeria

  • Department of Family Medicine, Federal Medical Centre, Umuahia, Abia state, Nigeria

  • Department of Family Medicine, Federal Teaching Hospital Abakiliki, Nigeria

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