American Journal of Health Research

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Prevalence of Toxoplasmosis in HIV/AIDS Patients in Mettu Karl Hospital

Received: 23 April 2015    Accepted: 11 May 2015    Published: 21 May 2015
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Abstract

Toxoplasma gondiiis food and waterborne opportunistic pathogen that causes severe disease in immunocompromised patients. It is caused by an obligatory intracellular protozoon. It causes a wide range of diseases with toxoplasma encephalitis commonly encountered in HIV/AIDS patients. It has been estimated that one-third of the human population is infected with this parasite. A sample of 120 HIV/AIDS patients has been taken from Mettu Karl Hospital. In this study logistic regression is applied for binary response data. To assess whether the model adequately fit to the data different model checking and model diagnostic have been applied. The study indicates that the prevalence of toxoplasmosis for HIV\AIDS patients in the study area was 60%. The analysis shows that some health, economic and risk behavior factors influence exposure of patients to toxoplasmosis. Further, the study shows that the risk factors of Toxoplasmosis are education, marital status, house toilet, tap water and washing hand and raw meat. The factor that influences toxoplasmosis status can be grouped as risk behavior factors (hand washing and raw meat), demographic and health factors (Education, marital status and house toilet) and economic factors (tap water). Under such grouping we can state that patients who are involved in risky behaviors will have higher risk of contracting toxoplasmosis.

DOI 10.11648/j.ajhr.20150303.23
Published in American Journal of Health Research (Volume 3, Issue 3, May 2015)
Page(s) 183-188
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Prevalence, Toxoplasmosis, HIV/AIDS

References
[1] Assob, J.C.N., Njunda, A.L., Nsagha, D.S., Kamga, H.L., Weledji, P.E. and Che, V.B. (2011). Toxoplasma Antibodies amongst HIV/AIDS Patients attending the University teaching Hospital Yaounde, in Cameroon.AFR. J. CLN. EXPER. MICROBIOL, 12: 1119-123.
[2] Boto, d.e., Los, B.A., Vega-Aleman, D., Galvez-Acebal, J., et al. (1998).Prevalence of latent toxoplasma infection in HIV infection patients. Ann Med Intern, 15: 298-300.
[3] Candolfi, E., Berg, M. &Kien, T. (1993). Prevalence of Toxoplasmosis in Pointe –Noire in Congo: study of the sampling of 310 subjects. Bulletin de la Société de pathologieexotiqueet de sesfiliales, 86: 358-62.
[4] Chantal, J., Bessiere, M.H., Guenno, Ble., Magnava, I.J.F. and Dorchies, P. (1996). A serological survey of some zoonotic diseases among abattoir personnel in Djibouti. (French) Bulletin de la Societe de Pathologie Exotique, 89:353-357.
[5] Davarpanah, M. A., Mehrabani, D., Neirami, R., Ghahremanpoori, M. and Darvishi, M. (2007).Toxoplasmosis in HIV/AIDS patients in Shiraz, southern Iran. Iranian Red Crescent Medical Journal, 9: 22-27.
[6] Ethiopia Demographic and Health Survey. Central Statistical Agency Addis Ababa, Ethiopia, September 2006 (USAID). Ethiopia. AIDS in Ethiopia. Fifth edition. June 2004.Ethiopia.
[7] Falusi, O., Fench, A.A., Seaberg, E.C., et al. (2002). Prevalence and predictors of toxoplasma seropositivity in women with and at risk for human immunodeficiency infection. Clin Infect Dis, 35: 1414-7.
[8] Fayomi, B., Duong, T.H., Karagirwa, A., Marquet, N., Djivoh, C. & Combescot, C. (1987).Serological study of Toxoplasmosis and echinococcosis in cattle breeders and abattoir personnel in Benin. Médecine Tropicale : Revue du Corps de santé colonial, 47:149-51.
[9] Fong, M.Y., Wong, K.T., Rohela, M., Tan, L.H., Adeeba, K., Lee, Y.Y. and Lau, Y.L. (2010).Unusual manifestation of cutaneous toxoplasmosis in a HIV-positive Patient. Tropical Biomedicine, 27:447-450.
[10] Holliman, R.E. (1990). Serological study of the prevalence of toxoplasmosis in asymptomatic patients infected with human immunodeficiency virus. Epidemiol.Infect.,105: 415-418.
[11] Hosmer, D.W. and Lemeshow,s., (2000, 2nd Ed.) “Applied Logistic Regression” John Wiley & Sons Inc., New York.
[12] Ibrahim, B.B., Salaam, M.M.I, Garish, N.I. and Hardy, F.M. (1997).Serological and histopathological studies on Toxoplasmagondiiamong the workers and the slaughtered animals in Tanta Abattoir, Gharbia Governate. Journal of the EgyptianSociety of Parasitology, 27:273-278.
[13] Luft, B.J. and Remington, J. S. (1988). Toxoplasmicencephalitis. J Infect., 157: pp.1-6
[14] Montoya, J. G. and Rosso, F. (2000).Diagnosis and management of toxoplasmosis. ClinPerinatol, 32: 705-726.
[15] Moura, L, Wada, M., Carmo, E, Dusi, R., Tuboi, S. H., Camargo, N. et al. (2002, April 23). Epidemic of toxoplasmosis associated with ingestion of contaminatedmunicipal water – Brazil. Paper presented at the Epidemic Intelligence Service 51st Annual Conference. Retrieved November 15, 2005
[16] Navia, B.A., Petito, C.K., Gold, J.W., Cho, E.S., Jordan, B.D. and Price, R.W. (1986). Cerebral toxoplasmosis complicating the acquired immune deficiency syndrome: clinical and neuropathological findings in 27 patients. Annals of Neurology, 19: 224-238.
[17] Osiyemi, T.I., Synge, E.M., Agbonlahor, D.E. & Agbavwe, R., (1985).The prevalence of Toxoplasma gondiiantibodies in man in Plateau State and meat animals in Nigeria. Transactions of the Royal Societyof Tropical Medicine & Hygiene,79: 21-30.
[18] Swai,E.S. and Schoonman, L. (2009). Seroprivalence of Toxoplasmosis gongii infection amongst residents of Tanga District in north-east Tanzania. Tanzania Journal of Health Research, 4:205-209.
[19] Techalew, S., Mekashaw, T., Endale, T., Belete, T. and Ashenafi, T. (2009).Sero-prevalence of latent Toxoplasma gondiiinfection among HIV-infected and HIV-uninfected people in Addis Ababa, Ethiopia: A comparative cross-sectional study. BMC Research Notes, 2:213. In: Kloos, H. and Berhane.Y. (2006): Pp. 692-700.
[20] Wallace, R.M., Rossetti, J.R., L.V.N. and Olson, E.P. (1993). Cats and Toxoplasmosis Risk in HIV- infected adults.JAMA, 269: 76-77.
[21] Wanachiwanawinm, D., Sutthent, R., Chokephaibulkit, K., Mahakittikun, V., Ongrotchanakun, J. and Monkong, N., (2001). Toxoplasma gondii antibodies in HIV and non-HIV infected Thai pregnant women. Asian Pac J Aller Immunol, 19: 291-293.
[22] Woldemicheal, T., Fontanet, A.L., Sahlu, T., Gilis, H., Messele, T., Rinke de Wit, T.F., Yeneneh, H., Coutinho, R.A. and Gool, T.V. (1998). Evaluation of the Eiken latex agglutination test for anti-Toxoplasma antibodies and seroprevalence of Toxoplasma infection among factory workers in Addis Ababa, Ethiopia.Trans R Soc Trop Med Hyg, 92:401-403.
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    Kasim Mohammed Yesuf, Zinabu Teka Melese. (2015). Prevalence of Toxoplasmosis in HIV/AIDS Patients in Mettu Karl Hospital. American Journal of Health Research, 3(3), 183-188. https://doi.org/10.11648/j.ajhr.20150303.23

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    ACS Style

    Kasim Mohammed Yesuf; Zinabu Teka Melese. Prevalence of Toxoplasmosis in HIV/AIDS Patients in Mettu Karl Hospital. Am. J. Health Res. 2015, 3(3), 183-188. doi: 10.11648/j.ajhr.20150303.23

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    AMA Style

    Kasim Mohammed Yesuf, Zinabu Teka Melese. Prevalence of Toxoplasmosis in HIV/AIDS Patients in Mettu Karl Hospital. Am J Health Res. 2015;3(3):183-188. doi: 10.11648/j.ajhr.20150303.23

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  • @article{10.11648/j.ajhr.20150303.23,
      author = {Kasim Mohammed Yesuf and Zinabu Teka Melese},
      title = {Prevalence of Toxoplasmosis in HIV/AIDS Patients in Mettu Karl Hospital},
      journal = {American Journal of Health Research},
      volume = {3},
      number = {3},
      pages = {183-188},
      doi = {10.11648/j.ajhr.20150303.23},
      url = {https://doi.org/10.11648/j.ajhr.20150303.23},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20150303.23},
      abstract = {Toxoplasma gondiiis food and waterborne opportunistic pathogen that causes severe disease in immunocompromised patients. It is caused by an obligatory intracellular protozoon. It causes a wide range of diseases with toxoplasma encephalitis commonly encountered in HIV/AIDS patients. It has been estimated that one-third of the human population is infected with this parasite. A sample of 120 HIV/AIDS patients has been taken from Mettu Karl Hospital. In this study logistic regression is applied for binary response data. To assess whether the model adequately fit to the data different model checking and model diagnostic have been applied. The study indicates that the prevalence of toxoplasmosis for HIV\AIDS patients in the study area was 60%. The analysis shows that some health, economic and risk behavior factors influence exposure of patients to toxoplasmosis. Further, the study shows that the risk factors of Toxoplasmosis are education, marital status, house toilet, tap water and washing hand and raw meat. The factor that influences toxoplasmosis status can be grouped as risk behavior factors (hand washing and raw meat), demographic and health factors (Education, marital status and house toilet) and economic factors (tap water). Under such grouping we can state that patients who are involved in risky behaviors will have higher risk of contracting toxoplasmosis.},
     year = {2015}
    }
    

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    AU  - Kasim Mohammed Yesuf
    AU  - Zinabu Teka Melese
    Y1  - 2015/05/21
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    DO  - 10.11648/j.ajhr.20150303.23
    T2  - American Journal of Health Research
    JF  - American Journal of Health Research
    JO  - American Journal of Health Research
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    EP  - 188
    PB  - Science Publishing Group
    SN  - 2330-8796
    UR  - https://doi.org/10.11648/j.ajhr.20150303.23
    AB  - Toxoplasma gondiiis food and waterborne opportunistic pathogen that causes severe disease in immunocompromised patients. It is caused by an obligatory intracellular protozoon. It causes a wide range of diseases with toxoplasma encephalitis commonly encountered in HIV/AIDS patients. It has been estimated that one-third of the human population is infected with this parasite. A sample of 120 HIV/AIDS patients has been taken from Mettu Karl Hospital. In this study logistic regression is applied for binary response data. To assess whether the model adequately fit to the data different model checking and model diagnostic have been applied. The study indicates that the prevalence of toxoplasmosis for HIV\AIDS patients in the study area was 60%. The analysis shows that some health, economic and risk behavior factors influence exposure of patients to toxoplasmosis. Further, the study shows that the risk factors of Toxoplasmosis are education, marital status, house toilet, tap water and washing hand and raw meat. The factor that influences toxoplasmosis status can be grouped as risk behavior factors (hand washing and raw meat), demographic and health factors (Education, marital status and house toilet) and economic factors (tap water). Under such grouping we can state that patients who are involved in risky behaviors will have higher risk of contracting toxoplasmosis.
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Author Information
  • Department of Statistics, College of Natural & Computational Sciences, University of Gondar, Gondar, Ethiopia

  • Department of Statistics, College of Natural & Computational Sciences, University of Gondar, Gondar, Ethiopia

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